Articles tagged "Infection"

2021 American Transplant Congress
Effect of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Individual Level and Within Twenty Five Race/ethnic Groups
H. C. Copley¹, L. Gragert², A. R. Leach³, V. Kosmoliaptsis¹
¹Department of Surgery, University of Cambridge, Cambridge, United Kingdom, ²Department of Pathology, Tulane University School of Medicine, New Orleans, LA, ³European Bioinformatics Institute (EMBL-EBI), Hinxton, United Kingdom
*Purpose: Development of adaptive immunity after COVID-19 and after vaccination against SARS-CoV-2 is predicated on recognition of viral peptides, presented on HLA class II molecules,…
2021 American Transplant Congress
Risk Factors and Outcomes of Neutropenia in Kidney Transplant Recipients
R. Avery¹, J. Motter¹, S. Sae-Tia², N. Lu¹, W. Cochran¹, A. Massie¹, D. Brennan¹, F. Akinwande¹, S. Shoham¹, E. Kraus¹, N. Alachkar¹, S. Alasfar¹, F. Naqvi¹, F. Al Ammary¹, K. Marr¹, S. Mehta Steinke¹, N. Desai¹, O. Ezennia¹, P. Plummer¹, C. Durand¹, W. Werbel¹, M. Y. Kim¹, D. Segev¹, J. Garonzik Wang¹, B. Trollinger¹, L. Lees¹, L. Toman¹, S. Shulder³, K. Dzintars¹, D. Ostrander¹
¹Johns Hopkins, Baltimore, MD, ²Stony Brook University, Stony Brook, NY, ³University of Rochester, Rochester, NY
*Purpose: Neutropenia is a common side effect of valganciclovir and may pose increased risk for post-transplant infections. Medications such as mycophenolate and infections such as…
2021 American Transplant Congress
COVID-19 in Hospitalized Kidney Transplant Recipients: Clinical Course, Prognostic Factors and Differences Between First and Second Waves
N. Macías, M. Rodríguez Ferrero, A. Acosta, J. Carbayo, Á. González Rojas, A. Muñoz de Morales, A. García Prieto, M. Goicoechea
Nephrology, Hospital Gregorio Marañón, Madrid, Spain
*Purpose: The aim was to describe the clinical course and management of SARS-CoV-2 infection in kidney transplant recipients (KTR) hospitalized with COVID-19, identify risk factors…
2021 American Transplant Congress
Variation of Mortality from SARS-CoV-2 Infection in Kidney Transplant Recipients Over the Course of the Pandemic
Y. Al Azzi, C. Pynadath, P. Loarte, O. Alani, L. Liriano-Ward, M. Ajaimy, R. Bartash, J. Graham, M. Le, H. Yaffe, S. Greenstein, J. Rocca, M. Kinkhabwala, E. Akalin
Montefiore Medical Center, New York, NY
*Purpose: We aimed to investigate the mortality from SARS-CoV-2 in kidney transplant recipients in the Bronx, New York, one of the epicenters of the pandemic…
2021 American Transplant Congress
Predictive Factors and Management of Urinary Tract Infections After Kidney Transplantation: A Retrospective Cohort Study
T. Shimizu, Y. Kinoshita, T. Shinzato, D. Iwami
Jichi Medical University, Shimotsuke City, Japan
*Purpose: Urinary tract infection (UTI) is one of the most common infectious complications in kidney transplant recipients. The predictive factors for UTI are controversial because…
2021 American Transplant Congress
Longitudinal Studies of Blood Anellovirus DNA Prior to Acute Rejection or Major Infection Events in Pediatric Kidney Transplant Recipients (PKTx)
R. Dandamudi, H. Gu, C. Goss, H. Gula, K. Wylie, V. Dharnidharka
Washington University in St Louis, St. Louis, MO
*Purpose: Blood levels of the ubiquitous but non-pathogenic anellovirus (AnV) taxa have been postulated to represent a biomarker of the overall state of immunosuppression after…
2021 American Transplant Congress
Enteric Conversion After Bladder-drained Kidney-pancreas Transplantation
S. Sivan, M. Ortigosa-Goggins, M. Patel, M. Morsi, L. Chen, J. Figueiro, G. Ciancio, G. Burke
Miami Transplant Institute, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL
*Purpose: In simultaneous kidney-pancreas transplantation (SPK), bladder (BD) and enteric (ED) are both options for pancreaticoduodenal exocrine drainage. While BD provides good early and long…
2021 American Transplant Congress
Trends in Mortality Among Solid Organ Transplant Recipients Hospitalized for Covid-19 During the Course of the Pandemic
M. R. Heldman, O. S. Kates, R. M. Rakita, E. D. Lease, C. E. Fisher, A. P. Limaye
University of Washington, Seattle, WA
*Purpose: Actual and comorbidity-adjusted mortality in hospitalized patients with COVID-19 has declined in the general population during the course of the pandemic. Whether a similar…
2021 American Transplant Congress
Characterization of Retransplantation Following Graft Failure Due to Bkvn
K. Nguyen¹, H. Curtis², J. Panichella², H. Resweber³, A. Di Carlo², S. Karhadkar¹
¹Surgery, Temple University School of Medicine, Philadelphia, PA, ²Surgery, Temple University School of Medicine, Philadephia, PA, ³Surgery, Temple University School of Medicine, Gladwyne, PA
*Purpose: Immunosuppression following kidney transplantation allows for the reactivation of BK polyomavirus (BKV)- frequently implicated in graft dysfunction and failure. Although BKV Nephropathy (BKVN) was…
2021 American Transplant Congress
Clinical Consequences in Patients Experiencing Leukopenia and Neutropenia After Solid Organ Transplant
A. Diamond¹, N. Diehl², K. Hiryak³, K. Mortia¹, J. Au¹, C. Ruggia-Check¹, H. Clauss⁴
¹Pharmacy, Temple University Hospital, Philadelphia, PA, ²Pharmacy, UPMC Pinnacle Health, Harrisburg, PA, ³Pharmacy, Temple University School of Pharmacy, Philadelphia, PA, ⁴Infectious Diseases, Temple University Hospital, Philadelphia, PA
*Purpose: The incidence of leukopenia and neutropenia in solid organ transplant (SOT) recipients can be influenced by medications required after transplant for immunosuppression and infection…