Articles tagged "Infection"

2021 American Transplant Congress
Utility of Non-Invasive Rejection Biomarkers to Guide Immunomodulation in Kidney Transplant Patients with Active Covid-19 Infection
J. Christensen, G. Gupta, A. Bryson, S. Paluri, R. Thompson, S. Sterling, N. Vissichelli, P. Kimball, D. Kumar
VCUHealth, Richmond, VA
*Purpose: Treatment of Coronavirus Disease 2019 (COVID-19) infection in organ transplant recipients has involved reduction of immunosuppression (IS). It is plausible that the cytokine release…
2021 American Transplant Congress
Torque Teno Virus Load Predicts Allograft Rejection but Not Viral Infection After Kidney Transplantation; A Cohort Joint Modelling Study
A. L. van Rijn¹, H. F. Wunderink², I. A. Sidorov¹, C. S. de Brouwer¹, A. C. Kroes¹, H. Putter³, A. P. de Vries⁴, J. I. Rotmans⁴, M. C. Feltkamp¹
¹Medical Microbiology, Leiden University Medical Center, Leiden, Netherlands, ²Medical Microbiology, University Medical Center Utrecht, Utrecht, Netherlands, ³Medical Statistics, Leiden University Medical Center, Leiden, Netherlands, ⁴Internal Medicine, Leiden University Medical Center, Leiden, Netherlands
*Purpose: The main challenge of immunosuppressive therapy after solid organ transplantation is to find the optimal dose regimen, and prevent allograft rejection as well as…
2021 American Transplant Congress
Immune Response to Covid-19 in Kidney Transplant Waitlist Patients
P. T. Jindra¹, C. M. Foye¹, I. Sharf², A. Rana¹, T. N. Galvan¹, A. Awan¹, C. A. O'Mahony¹, B. V. Murthy¹
¹Baylor College of Medicine, Houston, TX, ²Baylor St. Luke's Medical Center, Houston, TX
*Purpose: The purpose of this study was to determine the effect of SARS-CoV-2 infection on the immune response in Kidney Transplant Waitlist Candidates (KTWC) and…
2021 American Transplant Congress
Quantiferon-tb Gold Plus in Liver Transplant Candidates: Single-center Experience
J. Simkins¹, M. A. Mendoza¹, A. Chandorkar¹, Y. Natori¹, S. Anjan¹, L. R. Arosemena¹, R. Vianna²
¹Medicine, University of Miami, Miami, FL, ²Surgery, University of Miami, Miami, FL
*Purpose: QuantiFERON-TB (QFT) is the preferred diagnostic test for latent tuberculosis infection (LTBI). The QFT-Gold Plus (QFT-Plus) data in OLT candidates is limited.*Methods: Our hospital…
2021 American Transplant Congress
Discontinuation of Trimethoprim/sulfamethoxazole Prophylaxis Due to Hyperkalemia in Kidney Transplant Recipients
D. Pett¹, G. Malat², C. Domenico¹, R. Samudralwar¹, A. Forte¹, D. Sawinski², J. Hu¹, B. Steiner¹, J. Rashid¹, J. Trofe-Clark²
¹Pharmacy, Hospital of Univ of Pennsylvania, Philadelphia, PA, ²Penn Transplant Institute, Hospital of Univ of Pennsylvania, Philadelphia, PA
*Purpose: Trimethoprim-sulfamethoxazole (TMP-SMX) is the drug of choice for Pneumocystis jirovecii pneumonia (PJP) prophylaxis in kidney transplant recipients (KTRs), however, it can be complicated by…
2021 American Transplant Congress
Anterior Rectus Sheath versus Gibson Incision for Kidney Transplantation – University of Chicago Experience
G. S. Generette, P. J. Bachul, P. E. Borek, K. Jayant, A. Perez-Gutierrez, B. Juengel, Y. T. Becker, R. Barth, J. Fung, P. Witkowski
Surgery, University of Chicago, Chicago, IL
*Purpose: The advantages of Anterior Rectus Sheath (ARS) incision over traditional Gibson (GB) incision have been described for kidney transplantation. Therefore, we decided to compare…
2021 American Transplant Congress
SPK Transplantation in HIV-positive Recipients
H. Resweber, k. nguyen, H. Curtis, J. Panichella, A. DI Carlo, S. Karhadkar
Temple University School of Medicine, Philadelphia, PA
*Purpose: With the advent of anti-retroviral therapy in the treatment of HIV, mortality in HIV-infected individuals has become less due to complications from viral infection…
2021 American Transplant Congress
Prevalence and Dynamics of SARS-COV-2 IgG in Kidney Transplant Recipients
Y. Al Azzi, P. Loarte, C. Pynadath, O. Alani, L. Liriano-Ward, M. Ajaimy, R. Bartash, J. Graham, M. Le, H. Yaffe, S. Greenstein, J. Rocca, M. Kinkhabwala, E. Akalin
Montefiore Medical Center, New York, NY
*Purpose: We aimed to investigate the prevalence and dynamics of SARS-CoV-2 IgG in kidney transplant recipients in the Bronx, New York, one of the epicenters…
2021 American Transplant Congress
Molecular Epidemiology of Extended-Spectrum Cephalosporin-Resistant Enterobacterales Bloodstream Infections Among Solid Organ Transplant Recipients
J. A. Anesi¹, E. Lautenbach¹, P. D. Tamma², K. A. Thom³, K. Alby⁴, E. A. Blumberg¹, W. Bilker¹, J. Omorogbe¹, P. Tolomeo¹, A. Werzen³, J. Han⁵
¹University of Pennsylvania, Philadelphia, PA, ²Johns Hopkins University, Baltimore, MD, ³University of Maryland, Baltimore, MD, ⁴University of North Carolina, Chapel Hill, NC, ⁵GlaxoSmithKline, Rockville, MD
*Purpose: Solid organ transplant recipients (SOTR) have been significantly impacted by the emergence of multidrug-resistant bacteria, including extended-spectrum cephalosporin-resistant (ESC-R) Enterobacterales (EB). We determined the…
2021 American Transplant Congress
Solid Organ Transplant Recipients and Healthcare Burden in Covid19 Era
A. Basu, N. Sharma, R. Subramanian, L. Sridharan, S. Pastan, T. Pearson
Emory Healthcare, Atlanta, GA
*Purpose: Pneumonia(PNA)- Acute inflammation of the lung parenchyma from an infection, is a frequent cause for hospitalization among Solid Organ Transplant Recipients (SOTRs), adversely effecting…