Articles tagged "Infant"

2022 American Transplant Congress
Covid-related Neonatal Cholestasis?: Liver Transplantation In Three Infants With Intrauterine Or Perinatal Covid Exposure
S. Sakhuja¹, K. Patel¹, N. T. Galvan²
¹Baylor College of Medicine, Houston, TX, ²Baylor College of Medicine, Houston, TX
*Purpose: The COVID pandemic presents a unique set of challenges during pregnancy including thromboembolic complications, direct placental infection, transplacental transmission, and systemic hyperinflammatory state. The…
2021 American Transplant Congress
Galectin-3 Levels in Pediatric Cholestatic Liver Disease
D. Yoeli¹, Z. Wang¹, Y. Luo², A. Chaidez², M. A. Adams¹, C. A. Huang¹, C. L. Mack², N. Navarro Alvarez¹
¹Transplant Surgery, University of Colorado, Aurora, CO, ²Pediatric Gastroenterology, Hepatology and Nutrition, Children’s Hospital Colorado, Aurora, CO
*Purpose: Biliary atresia (BA) and other cholestatic liver diseases (CLD) are the most common indications for liver transplantation in children. Research on galectin-3, a protein…
2021 American Transplant Congress
Immunologic Benefits of Maternal Living Donor Allografts in Pediatric Liver Transplantation: Less Rejection Episodes and No Evidence of De Novo Allosensitization
A. Barbetta¹, G. Meeberg², B. Rocque¹, S. Barhouma³, S. Gilmour⁴, F. Faytrouni⁵, O. Guttman⁵, P. Campbell⁴, J. Shapiro², J. Emamaullee¹
¹Surgery, Abdominal Transplant, University of Southern California, Los Angeles, CA, ²Surgery, University of Alberta, Edmonton, AB, Canada, ³University of Southern California, Los Angeles, CA, ⁴University of Alberta, Edmonton, AB, Canada, ⁵University of British Columbia, Vancouver, BC, Canada
*Purpose: Living donor liver transplantation (LDLT) offers improved graft and patient survival in pediatric liver transplant (LT) recipients. Prior studies have suggested immunological advantage when…
2021 American Transplant Congress
Hepatoportoenterostomy versus Primary Liver Transplantation for Biliary Atresia: A Review of the National Experience
D. Yoeli¹, R. A. Choudhury¹, S. S. Sundaram², C. L. Mack², J. P. Roach³, F. M. Karrer⁴, M. E. Wachs¹, M. A. Adams¹
¹Transplant Surgery, University of Colorado and Children's Hospital Colorado, Aurora, CO, ²Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado and Children's Hospital Colorado, Aurora, CO, ³Pediatric Surgery, University of Colorado, Aurora, CO, ⁴Pediatric Surgery, University of Colorado and Children's Hospital Colorado, Aurora, CO
*Purpose: Kasai hepatoportoenterostomy (HPE) followed by liver transplantation (LT) if needed is the standard of care for children with biliary atresia (BA). Some, however, have…
2020 American Transplant Congress
ABH Subtype-Specific Tolerance after ABO-Mismatched Hematopoietic Cell Transplantation
B. Motyka¹, A. Halpin¹, J. Pearcey¹, A. Kariminia², A. Halevy², S. Maier¹, A. Halevy², P. Subrt², C. W. Cairo¹, G. D. Cuvelier³, K. R. Schultz², L. J. West¹
¹Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada, ²British Columbia Children’s Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada, ³CancerCare Manitoba, University of Manitoba, Winnipeg, MB, Canada
*Purpose: ABO-mediated immunity is reported to have minimal detrimental impact after ABO-mismatched hematopoietic cell transplantation (HCT). Patients are generally presumed ‘tolerant’ with regard to ABO.…
2019 American Transplant Congress
En Bloc Kidney Transplant from Infant Donors Less Than 5kg into Adult Recipients
Z. Wang, Q. Xia, M. Wang, H. Li, J. Liu, J. Liu, J. Liu
Urology, Union hospital, Wuhan, China
*Purpose: To explore the feasibility of en bloc kidney transplantation from infant donors less than 5kg into adult recipients.*Methods: A retrospective analysis was conducted of…
2019 American Transplant Congress
Absence of Antibodies in Human Neonates and Infants to Gtko/cmahko/β4galnt2ko (Triple Gene Knockout) Pig Cells: Relevance to Cardiac Xenotransplantation for Complex Congenital Heart Disease
H. Hara¹, Q. Li¹, C. A. Banks¹, T. Yamamoto¹, D. Ayares², D. C. Cleveland¹, D. K. Cooper¹
¹Surgery, University of Alabama at Birmingham, Birmingham, AL, ²Revivicor Inc., Blacksburg, VA
*Purpose: Heart transplantation (Tx) in neonates is associated with the best results of any organ Tx, but the lack of deceased human donor hearts in…
2019 American Transplant Congress
The High Burden of Vaccine Preventable Infections Following Pediatric Solid Organ Transplant
A. G. Feldman¹, B. L. Beaty², D. Curtis³, E. Juarez-Colunga², A. Kempe⁴
¹Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO, ²University of Colorado, Aurora, CO, ³Pediatric Infectious Diseases, University of Colorado, Aurora, CO, ⁴Pediatrics, University of Colorado, Aurora, CO
*Purpose: Pediatric transplant recipients are at risk for vaccine preventable infections due to immunosuppression, suboptimal response to vaccines before and after transplant, and potential under-immunization…
2019 American Transplant Congress
Immunization Status at the Time of Pediatric Liver Transplant: A 1-year Study through The Society of Pediatric Liver Transplantation
A. G. Feldman¹, A. Kempe², B. L. Beaty³, R. Torres¹, D. Curtis⁴, S. S. Sundaram¹
¹Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO, ²Pediatrics, University of Colorado, Aurora, CO, ³University of Colorado, Aurora, CO, ⁴Pediatric Infectious Diseases, University of Colorado, Aurora, CO
*Purpose: Vaccine preventable infections are a serious and common complication following transplant. Immunizations are a minimally invasive and cost-effective approach to reducing infections. The objectives…
2019 American Transplant Congress
Barriers to Pre-Transplant Immunization: A Qualitative Study of Pediatric Liver-Transplant Stakeholders
A. G. Feldman¹, R. Marsh², A. Kempe³, M. Morris²
¹Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO, ²University of Colorado, Aurora, CO, ³Pediatrics, University of Colorado, Aurora, CO
*Purpose: Less than 30% of pediatric liver transplant recipients are up-to-date on age-appropriate immunizations at the time of transplant despite being at high-risk for infections…