ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Induction therapy"

  • 2020 American Transplant Congress

    Comparison of 1-Year Incidence of De Novo Donor Specific Antibodies between Thymoglobulin and Alemtuzumab Induction in Kidney Transplantation

    J. P. Knorr, C. Kallis, D. A. Portley, A. Jeyarajasingam, P. W. Lai, G. Bradauskaite, K. Khanmoradi

    Transplant Nephrology, Einstein Medical Center, Philadelphia, PA

    *Purpose: Development of de novo donor specific antibodies (dnDSA) after kidney transplantation (KTx) has been associated with acute and chronic antibody-mediated rejection, transplant glomerulopathy and…
  • 2020 American Transplant Congress

    Enough Initial Tacrolimus Blood Concentration is Crucial Even with Additional Everolimus in Corticosteroid Early Withdrawal Regimen for Kidney Transplant Recipients

    H. Sasaki1, T. Tanabe1, H. Higuchi1, T. Tsujimoto2, H. Harada1

    1Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan, 2Pharmacy, Sapporo City General Hospital, Sapporo, Japan

    *Purpose: Everolimus (EVR) in combination with low-dose calcineurin inhibitor has been demonstrated in clinical trials to have comparable efficacy in low immunological risk kidney transplant…
  • 2020 American Transplant Congress

    Pediatric Primary Kidney Transplant Recipients Outcomes by Immunosuppression Induction Received in the United States

    S. M. Riad1, S. Jackson2, A. Matas3, S. Chinnakotla3, P. Verghese4

    1University of Minnesota, Minneapolis, MN, 2Complex Care Analytics, Fairview Health Services, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN, 4Pediatrics, University of Minnesota, Minneapolis, MN

    *Purpose: Induction immunosuppression types for pediatric transplant recipients vary widely by transplant centers. We sought to study the impact of different induction types on recipients…
  • 2020 American Transplant Congress

    Basiliximab vs Antithymocyte Globulin Induction with Early Steroid Withdrawal in Kidney Transplant Recipients: Early Rejection Outcomes

    A. Szczepanik1, C. Burrelli1, A. Bixby1, K. Yadav2, K. Chavin2

    1Pharmacy, University Hospital Cleveland Medical Center, Cleveland, OH, 2Surgery, University Hospital Cleveland Medical Center, Cleveland, OH

    *Purpose: Steroid withdrawal within the first month of kidney transplant (KT) remains controversial and has demonstrated a higher risk of acute rejection. The impact of…
  • 2020 American Transplant Congress

    Renal Transplant Induction Therapy Safety Outcomes Comparison

    R. M. Hofmann1, J. Combs2, K. J. Schmidt3, T. Dyckman4

    1Nephrology, Renal Associates of West Michigan, Grand Rapids, MI, 2Pharmacy/Transplant, Mercy Health St. Mary's, Grand Rapids, MI, 3Pharmacy, Ferris State University College of Pharmacy, Big Rapids, MI, 4Pharmacy, Mercy Health St. Mary's, Grand Rapids, MI

    *Purpose: Induction immunosuppression with alemtuzumab and rabbit anti-thymocyte globulin (r-ATG) reduces acute rejection following kidney transplantation. Efficacy is thought to be similar between the agents…
  • 2020 American Transplant Congress

    Depletional Induction Improves Kidney Graft and Patient Survival in Recipients with a Previous Liver Transplant in the United States

    S. M. Riad1, N. Lim1, S. Jackson2, A. Matas3, J. Lake1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Fairview Health Services, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: Induction choices for kidney-after-liver transplant recipients are variable. We examined the impact of kidney induction types on kidney graft and patient survival in liver…
  • 2020 American Transplant Congress

    Differences in Alemtuzumab Dosing Does Not Affect Early Kidney Transplant Outcomes

    A. Pressley, R. Stratta, J. Rogers, A. Farney, G. Orlando, W. Doares, A. Reeves-Daniel, C. Jay

    Wake Forest Baptist Health, Winston-Salem, NC

    *Purpose: Alemtuzumab (Alem) is a widely used medication for induction therapy in kidney transplantation. However, there is limited evidence comparing outcomes with low versus high…
  • 2020 American Transplant Congress

    Causal Relationship between Anti-Thymocyte Globulin Induction Therapy and Development of Monomorphic PTLD in Renal Transplant Recipients

    K. Soliman1, H. Ali2, T. Fulop1, A. Osman3, A. Halawa4

    1Medicine, Medical University of South Carolina, Charleston, SC, 2Medicine, Royal Stoke, Royal Stoke, United Kingdom, 3Medicine, Cairo University, Cairo, Egypt, 4Medicine, University of Liverpool, Liverpool, United Kingdom

    *Purpose: The aim of our study is to explore the causality between ATG and different types of post-transplant lymphoproliferative disorder (PTLD) in renal transplant recipients…
  • 2019 American Transplant Congress

    Association Of Lymphocyte-depleting Antibody And Steroids Induction With The Risk And Outcomes Of Post-transplant Diabetes: Analysis Of Deceased-donor Kidney Transplants

    A. Santos1, J. Gregg2, U. L. Akanit3, K. Alquadan1, H. Bejjanki1, K. L. Womer1

    1Div. of Nephrology, Hypertension & Renal Transplantation, University of Florida, Gainesville, FL, 2University of Florida, Gainesville, FL, 3Ubon Ratchathani University, Ubonratchathani, Thailand

    *Purpose: We aimed to determine the risk and outcomes of post-transplant diabetes(PTDM) associated with combined lymphocyte-depleting antibody (LDA) [anti-thymocyte globulin (ATG) or alemtuzumab (ALM)] and…
  • 2019 American Transplant Congress

    Combined Antithymocyte Globulin (ATG) and Rituximab (RTX) Induction in African American (AA) Kidney Transplant Recipients

    S. J. Patel, S. Kuten, C. Pham, R. Knight, M. Hobeika, D. Nguyen, E. Graviss, S. Yi, T. Eagar, A. Gaber

    Methodist Hospital, Houston, TX

    *Purpose: We have previously shown that despite the use of T cell-depleting antibody induction, AA kidney transplant recipients (KTR) remain at high risk of rejection…
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