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American Transplant Congress abstracts

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Articles tagged "Induction therapy"

  • 2020 American Transplant Congress

    Comparative Study between ATG and Grafalon as Induction Agent in Renal Transplant Recipient

    L. K. Das, P. Paudyal, S. Shrestha, B. Shahi, A. Pandey, R. Verma, P. Chandra Shrestha

    Kidney and Liver Transplant, Shahid Dharmabhakta National Transplant Center, Kathmandu, Nepal

    *Purpose: Renal transplantation (Rtx) remains the most effective treatment for of end-stage renal disease (ESRD). The development of induction therapy has significantly reduced the incidence…
  • 2020 American Transplant Congress

    Donor-Derived Cell-Free DNA Levels During Early Rejection after Kidney Transplant May Be Impacted by Type of Induction Agent Received

    M. Gillespie, K. Lim, A. Vo, E. Huang, N. Ammerman, A. Peng, R. Najjar, S. Sethi, S. Jordan

    Cedars-Sinai, Los Angeles, CA

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) is an injury biomarker that detects rejection in kidney transplant recipients (KTR). It is reported as % cfDNA from the…
  • 2020 American Transplant Congress

    Incident Malignancies among Post Kidney-Transplant Patients by Type of Induction Immunosuppression and by Age

    L. Wang, J. Motter, S. Bae, D. Segev, M. McAdams DeMarco

    Johns Hopkins University, Baltimore, MD

    *Purpose: Adult kidney-transplant (KT) recipients have a differential risk of malignancies based on their induction immunosuppression (IS) therapy. However, older recipients are more likely to…
  • 2020 American Transplant Congress

    Efficacy and Safety of Single-Dose Rabbit Anti-Thymocyte Globulin versus Basiliximab Induction among Pediatric Kidney Transplant Recipients

    L. Porini Custodio, S. Stopa Martins, L. Almeida Viana, M. Pontello Cristelli, M. Rika Nakamura, H. Tedesco-Silva, J. Medina-Pestana

    Hospital do Rim, Sao Paulo, Brazil

    *Purpose: Induction therapy is a standard component of kidney transplant immunosuppression protocols. However, in the pediatric population, there are still uncertainties about the ideal induction…
  • 2020 American Transplant Congress

    Safety and Efficacy of Low Dose Rabbit Antithymocyte Globulin in Pediatric Renal Transplant Recipients

    V. K. Sigurjonsdottir1, L. Maestretti1, A. McGrath1, A. Gallo2, W. Concepcion2, P. Grimm1, A. Chaudhuri1

    1Pediatric Nephrology, Stanford University, Stanford, CA, 2Surgery - Multi-Organ Transplantation, Stanford University, Stanford, CA

    *Purpose: Currently there is no consensus among pediatric kidney transplant centers regarding the use and regimen for immunosuppressive induction therapy.The safety and effectiveness of reduced…
  • 2020 American Transplant Congress

    Single-Dose Anti-Thymocyte Globulin is Non-Inferior to Divided-Dose for Induction Therapy in Kidney and Pancreas Transplantation

    A. I. Ingemi1, O. F. Bangash1, S. McCoy1, L. Hulse2, J. Colonna1, H. Sadr1, S. Sutton1, M. Coleman1, T. Wilson1, T. R. McCune1

    1Sentara Norfolk General Hospital, Norfolk, VA, 2Children's Hospital of the King's Daughters, Norfolk, VA

    *Purpose: Emerging studies suggest that single-dose rabbit antithymocyte globulin (rATG) is not inferior to the divided-dose, however this dosing strategy has never been evaluated in…
  • 2020 American Transplant Congress

    Adult Primary Liver Transplant Recipient Outcomes by Immunosuppression Induction Received

    T. Shaker1, G. Larrieux1, S. Jackson2, S. Riad3, T. Pruett1, T. Leventhal4

    1Surgery, Division of Transplantation, University of Minnesota, Minneapolis, MN, 2M Health Fairview, Minneapolis, MN, 3Division of Renal Diseases and Hypertension, University of Minnesota, Minneapolis, MN, 4Division of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis, MN

    *Purpose: It has long been recognized that the highest risk of rejection of an organ is in the first few months post transplantation. To prevent…
  • 2020 American Transplant Congress

    Basiliximab Induction in the Obese: One Size Does Fit All

    A. D. Reticker1, D. Choi1, A. B. Lichvar1, C. Kane2, I. Tzvetanov3, E. Benedetti3, J. J. Benken1

    1Pharmacy Practice, University of Illinois Hospital and Health Sciences System, Chicago, IL, 2Pharmacy, Northwestern Memorial Hospital, Chicago, IL, 3Surgery, University of Illinois Hospital and Health Sciences System, Chicago, IL

    *Purpose: Surgical advancements allow more obese (BMI> 30 kg/m2) patients to receive a renal transplant. The original clinical and pharmacokinetic (PK) trials in transplantation immunosuppression…
  • 2020 American Transplant Congress

    The FcγRIIIa-158 VV Genotype Increased the Risk of Post-Transplant Lymphoproliferative Disorder in T-Cell Depleted Kidney Transplant Recipients

    P. Gatault1, L. Lajoie1, J. Stojanova2, P. Marquet2, G. Thibault1

    1CHU Tours, Tours, France, 2CHU Limoges, Limoges, France

    *Purpose: Post-transplantation lymphoproliferative disorder (PTLD) is a severe complication in organ transplant recipients. The use of T lymphocyte-depleting antibodies (TLDAb), especially rabbit TLDAb contributes to…
  • 2020 American Transplant Congress

    Induction Immunosuppression with Thymoglobulin May Improve Graft Outcomes without Increasing a Risk for Infection in Patients Undergoing Liver Transplantation Alone

    M. Henry1, T. Kitajima2, J. Konel1, S. Yeddula2, M. Rizzari2, K. Collins2, D. Moonka2, A. Yoshida2, M. Abouljoud2, S. Nagai3

    1Wayne State University School of Medicine, Detroit, MI, 2Henry Ford Hospital, Detroit, MI, 3Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI

    *Purpose: Immunosuppression protocols for liver transplant (LT) vary between institutions and roles of induction immunosuppression in LT remain controversial. The aim of this study was…
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