ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Induction therapy"

  • 2015 American Transplant Congress

    Reduced Intensity Immunosuppression Protocol Lowers Drug Costs and May Decrease Incidences of BK Viremia and Readmissions After Kidney and Kidney/Pancreas Transplant

    M. Mariski,1 A. DeGolovine,2 W. Dar,2 J. Bynon,2 H. Adrogué,2 M. Hobeika.2

    1Dept of Pharmacy, Memorial Hermann Texas Medical Center, Houston, TX; 2Division of Immunology and Organ Transplantation, University of Texas, Houston, TX.

    Purpose: To evaluate the effects of a reduced intensity immunosuppression protocol on drug costs and rates of BK viremia and readmissions.Methods: In response to high…
  • 2015 American Transplant Congress

    Effectiveness of Protocol-Driven Induction Therapy in Adult Kidney Transplant Recipients

    J. Casale, J. Fleming, D. Taber, C. Staino, K. Boyle, K. Covert, N. Pilch, H. Meadows, C. Mardis, K. Chavin, C. Bratton, J. McGillicuddy, T. Srinivas, P. Baliga.

    MUSC, Charleston, SC.

    Background: Induction therapy significantly improves graft outcomes in kidney transplantation, but the optimal agent based on patient characteristics and immunologic risk is unknown. While many…
  • 2015 American Transplant Congress

    Early Use of Anti-Lymphocyte Antibody in Kidney Transplant Recipients With Delayed Graft Function Can Produce Desirable Post-Transplant Results

    J. Lee, J. Lee, D. Joo, K. Huh, S. Kim, Y. Kim, M. Kim.

    Department of Transplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea.

    Proper management of delayed graft function (DGF) is essential for successful post-transplant result in deceased donor kidney transplantation. We compared the effect of anti-lymphocyte antibody…
  • 2015 American Transplant Congress

    Alemtuzumab Induction Is Protective Against Acute Rejection in Kidney Recipients With Subtherapeutic Tacrolimus Concentrations

    K. Szempruch, R.-A. Lee, R. Dupuis, J. Deyo, T. Kozlowski.

    Transplant Surgery, University of North Carolina Hospitals, Chapel Hill, NC.

    Purpose: To determine the effect of attaining early therapeutic tacrolimus (TAC) trough concentrations on biopsy-proven acute rejection (BPAR) within 12 months post-transplantation in adult kidney…
  • 2015 American Transplant Congress

    Induction of a Costimulation-Susceptible Repertoire: A Case for Depletional Prior to Belatacept

    H. Xu,1 K. Samy,1 A. Guasch,2 S. Mead,2 A. Kirk.1

    1Surgery, Duke University, Durham, NC; 2Transplant Center, Emory University, Atlanta, GA.

    Belatacept offers highly specific costimulation blockade to prevent recipient alloimmune responses with reduced toxicity. However, when applied with nondepletional induction therapy belatacept-based regimens have higher…
  • 2015 American Transplant Congress

    Effect of Induction in Renal Transplant Recipients Aged 70 and Over

    M. Lubetzky, M. Ajaimy, L. Kamal, G. DeBoccardo, E. Akalin.

    Transplantation, Montefiore Medical Center, Bronx, NY.

    While there is a significant survival advantage to transplanting patients 70 years of age and older versus staying on dialysis, it is unclear whether sensitized…
  • 2015 American Transplant Congress

    Preliminary Results of a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab in a Pediatric Patient Population Undergoing Kidney Transplantation

    D. Halleran,1 S. Schurman, T. Welch, V. Whittaker.

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Pediatric Nephrology, State University New York Upstate Medical University, Syracuse, NY.

    Purpose: We report the outcomes from single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative day…
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