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American Transplant Congress abstracts

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Articles tagged "Induction therapy"

  • 2015 American Transplant Congress

    Single Center Experience With the Use of an Abbreviated Anti-Thymocyte Globulin and Basiliximab Combination Protocol in Renal Transplantation

    V. Whittaker,1 D. Halleran,1 S. Narsipar,1 J. Melancon.2

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Surgery, George Washington University, Washington, DC.

    Purpose: To report one year outcomes from single center experience with a novel induction regimen using anti-thymocyte globulin ( ATG)(rabbit)rATG (3 mg/kg) in divided doses…
  • 2015 American Transplant Congress

    Alemtuzumab in Elderly Renal Transplant Recipients Is Not Associated With a Poor Outcome

    D.-A. Moutzouris, L. Koizia, M. Willicombe, R. Corbett, N. Duncan, J. Galliford, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    The use and choice of induction immunosuppression in elderly kidney recipients remains unresolved. Alemtuzumab has been associated with a higher risk of death and graft…
  • 2015 American Transplant Congress

    Renal Function Following Basiliximab Induction in Liver Transplant Recipients

    J. Hagopian, T. Horwedel, L. Bowman, K. Collins, M. Doyle.

    Washington University School of Medicine, St. Louis.

    Purpose: Reports of the use of antibody induction to delay the start of calcineurin inhibitor therapy postoperatively in patients with renal insufficiency at the time…
  • 2015 American Transplant Congress

    Kidney Patients at High Immunological Risk Can Be Safely Transplanted With a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab

    D. Halleran,1 J. Melancon,2 V. Whittaker.1

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Surgery, George Washington University, Washington, DC.

    Purpose: We report the outcomes from our single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative…
  • 2015 American Transplant Congress

    Immunomodulation of Human T Cells by a Novel RALG Preparation With Higher Specificity Toward Activating T Cells

    K. Samy, H. Xu, A. Kirk.

    Surgery, Duke University Medical Center, Durham, NC.

    Current induction therapy using thymoglobulin (ATG) results in nonspecific T cell depletion. We have generated a polyclonal rabbit anti-human leukocyte globulin (RALG) by immunizing rabbits…
  • 2015 American Transplant Congress

    Tracking T Cell Fate After Antithymocyte Globulin (ATG) Immunotherapy in Infant Heart Transplant (HTx) Patients

    S.-I. Wang,1,2 I. Larsen,1,2 S. Urschel,1,2 R. Chinnock,3 J. Rusch,3 L. West.1,2

    1Univ. of Alberta, Edmonton, Canada; 2Alberta Transplant Institute, Edmonton, Canada; 3Loma Linda Univ., Loma Linda.

    Polyclonal T cell depletion with ATG is a common induction therapy in adult and pediatric transplantation. In adults, T cell recovery post-ATG involves homeostatic proliferation…
  • 2015 American Transplant Congress

    Thymoglobulin Dosing Efficacy: The Role of ALC on Infection and Rejection

    H. Sarumi, C. Borscheid, G. Sieger, B. Fast, S. Hogan, K. Vassar, T. Pruett.

    University of Minnesota, Minneapolis, MN.

    There are varied Thymoglobulin® (Thymo) induction regimens accepted among transplant programs. Our center uses five doses of Thymo at 1.25mg/kg, yielding a total goal of…
  • 2015 American Transplant Congress

    Current Status of US Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Intestine Transplant Registry

    J. Cai,1 A. Qing,2 G. Wu,3 M. Everly,1 P. Terasaki.1

    1Terasaki Foundation Lab, Los Angeles, CA; 2Lincoln High School, Stockton, CA; 3The 4th Military Medical University, Xi-An, China.

    The purpose of this study is to analyze the current status of US intestinal transplantation (IT). As of 9/19/2014, 2441 IT have been performed in…
  • 2015 American Transplant Congress

    Induction Therapy (IT) in Simultaneous Pancreas and Kidney Transplantation (SPK) according to Patient Risk – A Registry Analysis

    R. Gruessner,1 A. Gruessner.2

    1Department of Surgery, University of Arizona, Tucson, AZ; 2College of Public Health, University of Arizona, Tucson, AZ.

    Purpose: Optimal IT in SPK recipients (rec) according to patient risk has not been studied.Methods: Using the International Pancreas Transplant Registry database, we analyzed IT…
  • 2015 American Transplant Congress

    Alemtuzumab Dose Adjusted for Weight Reduces Infection Post-Renal Transplantation

    C.-H. Yoon, M. Willicombe, C. Jogia, R. Charif, J. Galliford, A. McLean, D. Taube.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Alemtuzumab [AL] has been increasingly used as an induction agent in renal transplantation. It causes potent lymphocyte depletion and as has been shown to reduce…
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