2016 American Transplant Congress
Induction Agent Use and Outcomes in Older KT Recipients: Patient and Center Level Associations.
Background: Clinical trials of induction agents typically exclude older recipients, so our practice in older recipients is extrapolated from this. Older adults are different, so…2016 American Transplant Congress
Induction Therapy with Rabbit Antithymocyte Globulin (rATG, Thymoglobulin®) vs Basiliximab After Kidney Transplantation: A Health Economic Analysis from a German Perspective.
Study objective. A health economic analysis was undertaken to quantify the economic consequences of acute rejection and serious adverse events in patients receiving induction with…2015 American Transplant Congress
10 Year Experience Using a Steroid Free Three Drug Maintenance Immunosuppression Regimen for Pancreas Transplant Alone: Comparison of Induction With Rabbit Antithymocyte Globulin +/- Rituximab
Graft survival following pancreas transplant alone (PTA) is inferior to other pancreas transplants. Steroid elimination is appealing, but a two drug maintenance strategy may be…2015 American Transplant Congress
Molecular Features of Kidney Transplant Biopsies Without Allograft Injury in Relation With Type of Induction Therapy
Objective: Molecular evidence of allograft injury might precede histopathological findings of allograft injury. We aimed to investigate if the type of induction therapy effect intragraft…2015 American Transplant Congress
Campath Induction With Triple Maintenance Therapy in African American Kidney Transplant Recipients: Less Infections But Worse Graft Survival
University of Maryland Medical Center, Baltimore, MD.
Introduction:African American (AA) kidney transplant recipients (KTR) are at a higher risk for worse clinical outcomes vs non-AA. Strategies to improve outcomes in AA KTR…2015 American Transplant Congress
Thymoglobulin Versus IL2RA: Three Year Results of a Randomized Controlled Trial
Transplant, MUSC, Charleston, SC.
This is a three year follow-up of a prospective, randomized controlled trial (RCT) to determine the safety and efficacy of induction with rabbit antithymocyte globulin…2015 American Transplant Congress
IL-17 Production Influenced by Induction Therapy With ATG
Introduction Immune-mediated rejection remains the most important cause of graft failure. Recently, a newly identified CD4+ T cell subset, Th17, distinct from Th1 or Th2,…2015 American Transplant Congress
T-Cell Depletion Versus Interleukin-2 Antagonists in a Kidney Transplant Model of Sensitized Rhesus Macaques
[Background] Sensitized patients comprise up to a third of the kidney waiting list. Preformed and newly formed alloantibodies post transplantation (TX) deteriorate graft survival, recall…2015 American Transplant Congress
Impact of Induction Therapy on Outcomes in HIV + Renal Transplant Recipients
Purpose: Kidney transplantation in HIV+ recipients has been complicated by higher than expected acute rejection rates (AR). Induction immunosuppression may or may not impact this…2015 American Transplant Congress
The Relationship Between Age and Morbidity During the First Year Following Renal Transplantation in Patients Receiving Alemtuzumab Induction
Vanderbilt University Medical Center, Nashville.
BackgroundThe elderly (age ≥ 65) represent the largest growing patient population being listed for renal transplant. Immunosuppression in elderly patients presents a unique challenge, with…
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