ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Induction therapy"

  • 2017 American Transplant Congress

    Induction Treatment with Rabbit Antithymocyte Globulin versus Basiliximab in Renal Transplant Recipients with Planned Early Steroid Withdrawal.

    S. Gabardi.

    Transplant Surgery, Brigham and Women's Hospital, Boston

    Introduction: In a previous study by our group, rabbit antithymocyte globulin (r-ATG) induction was associated with lower rates of rejection when compared to basiliximab in…
  • 2017 American Transplant Congress

    IL-7 Receptor Heterogeneity as a Mechanism for Repertoire Change During Post-Depletional Homeostatic Proliferation and Its Relation to Costimulation Blockade Resistant Rejection.

    H. Xu, T. Brennan, A. Kirk.

    Department of Surgery, Duke University School of Medicine, Durham, NC

    Transplant patients treated with belatacept without depletional induction show high rates of costimulation blockade resistant rejection (CoBRR); this has been associated with CD57+ T cells.…
  • 2017 American Transplant Congress

    The Impact of Induction Therapy on Delayed Graft Function Following Kidney Transplantation in Mated Kidneys.

    T. Butler, N. Hayde.

    Department of Transplantation, Albert Einstein-Montefiore, Bronx, NY

    Purpose: Delayed graft function (DGF) is defined as the need for dialysis within one week of transplantation and occurs in 20-50% of deceased-donor kidney transplant…
  • 2017 American Transplant Congress

    Risk of Primary Central Nervous System Lymphoma in Solid Organ Transplant Recipients.

    E. Engels, P. Mahale, M. Shiels.

    National Cancer Institute, Bethesda, MD

    Background: Risk of primary central nervous system lymphoma (PCNSL) is greatly increased in immunosuppressed HIV-infected people. Case series describe PCNSL in solid organ transplant (SOT)…
  • 2017 American Transplant Congress

    Incidence of Acute Rejection and Donor Specific Antibodies in Low-Immunological Risk Patients Treated by Tacrolimus and Mycophenolic Acid with or without Induction Therapy.

    O. Marion,1 A. Del Bello,1 I. Ferrandiz,1 L. Esposito,1 N. Congy,2 A.-L. Hebral,1 N. Kamar.1

    1Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Laboratory of Histocompatibility, CHU Rangueil, Toulouse, France

    The need for using induction therapy in de novo non-HLA sensitized kidney-transplant patients receiving tacrolimus-based therapy is a matter of debate. The aims of this…
  • 2016 American Transplant Congress

    The BEST Trial: A Prospective Randomized Trial of Belatacept-Based, CNI- and Corticosteroid-Free Immunosuppression.

    E. Woodle,1 D. Kaufman,2 A. Shields,1 J. Leone,3 A. Matas,4 A. Wiseman,5 P. Thielke,6 R. Alloway.1

    1U Cincinnati, Cinci; 2U Wisconsin, Madison; 3Tampa General, Tampa; 4U Minnesota, Minn; 5U Colorado, Denver; 6U Illinois Chicago, Chic.

    Efficacy of CNI- and corticosteroid-free immunosuppressive regimens has not been demonstrated in large, multicenter trials. BEST (Belatacept-based Early Steroid Withdrawal Trial) (NCT 01729494) compares 2…
  • 2016 American Transplant Congress

    Serum Levels of Soluble Myeloid Antigens After Kidney Allograft Transplantation.

    I. Striz, E. Cecrdlova, A. Sekerkova, J. Slatinska, V. Svachova, O. Viklicky.

    Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic.

    Mononuclear phagocytes and neutrophils play a key role in early responses against the transplanted kidney allograft. It is expected that during the reperfusion of kidney…
  • 2016 American Transplant Congress

    B Cell Signature Profiling in Kidney Transplant Patients on Thymoglobulin.

    A. Benitez,1 T. Milford,2 K. Torralba,3 K. Payne,2 M. De Vera.1

    1Transplantation Institute, Loma Linda University Health Care, Loma Linda, CA; 2Basic Science Division of Anatomy, Loma Linda University, Loma Linda, CA.

    Purpose: B cell subsets could be used as biomarkers to modulate therapy regimens in kidney transplant patients. B cell subsets occur with varying proportions within…
  • 2016 American Transplant Congress

    Calcineurin Inhibitor (CNI) Delay with ATG Induction: Teaching an Old Dog, New Tricks.

    A. Aliabadi,1 J. Goekler,1 O. Salameh,1 T. Haberl,1 B. Steinlechner,2 P. Opfermann,2 A. Kaider,1 K. Uyanik-Uenal,1 G. Laufer,1 A. Zuckermann.1

    1Cardiac Surgery, Medical University of Vienna, Vienna, Austria; 2Cardiothoracic and Vascular Anaesthisiology, Medical University of Vienna, Vienna, Austria.

    CNI delay early after heart transplantation is a recommended therapeutic option according to ISHLT guidelines. However, there exist only few published data on feasibility of…
  • 2016 American Transplant Congress

    Alemtuzumab Induction Allows Better Rejection Free Graft Survival in Comparison to Basiliximab Although with Increased Post Transplant Viral Infections.

    V. Siddagangaiah,1 H. Sharma,2 N. Lal,1 J. Rai,1 M. Howse,1 D. Ridgway,1 A. Sharma,1 A. Hammad,1 S. Mehra.1

    1Renal Transplant Surgery, Royal Liverpool and Broadgreen University Hospital, Liverpool, United Kingdom; 2Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.

    Introduction: 3C study concluded that in comparison to basiliximab, alemtuzumab induction reduces the risk of biopsy proven acute rejection (BPAR) in renal transplant recipients. In…
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