Articles tagged "Induction therapy"

2019 American Transplant Congress
Living Donor Renal Transplantation without Any Induction Immunosuppression in Spousal Donors – Single Center Experience
R. Bhat, F. Aziz, I. N. Abubecker, S. Narayanan, B. Hafeeque
Nephrology & Transplantation, Malabar Instiute of Medical Sciences, Calicut, India
*Purpose: Renal transplantation in India is primarily driven by living related donation; parents and spouse constitute 70% of donors in India. Some centres use induction…
2019 American Transplant Congress
A Prospective, Randomized, Multicenter Trial of Bela-Based CNI Free and Steroid Withdrawal Immunosuppression: Best Trial Two Year Characterization of Rejection and Renal Function
A. Wiseman¹, A. R. Shields², R. R. Alloway², D. Kaufman³, J. P. Leone⁴, A. J. Matas⁵, P. West-Thielke⁶, J. Lipscomb², E. King², E. S. Woodle for the BEST Study Group²
¹University of Colorado School of Medicine, Denver, CO, ²University of Cincinnati, Cincinnati, OH, ³University of Wisconsin, Madison, WI, ⁴Tampa General, Tampa, FL, ⁵University of Minnesota, Minneapolis, MN, ⁶University of Illinois, Chicago, Chicago, IL
*Purpose: The BEST Trial (Belatacept-based Early Steroid Withdrawal Trial) was designed to compare two BELA-based early steroid withdrawal (ESW) regimens with a TAC-based ESW regimen…
2019 American Transplant Congress
Effect of ATG on Monocytic Myeloid-Derived Suppressor Cells and Its Associated Mechanisms in Kidney Transplantation Recipients
Y. Jiang, X. Zhang
Beijing Chao-yang Hospital, Beijing, China
*Purpose: Myeloid-derived suppressor cells (MDSCs) consist of heterogeneous myeloid progenitors and precursors that was first defined in cancer patients and are characterized by a immunoregulatory…
2019 American Transplant Congress
Induction with Thymoglobulin in DCD Kidneys. Dose Effect and Predictors of Outcome
A. Asderakis, T. Sabah, A. Jones, E. Ablorsu, L. Szabó, R. Chavez
Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom
*Purpose: Thymoglobulin (ATG) is used only in few UK centres as induction. We have previously shown good results with ATG for pancreas transplants. The aim…
2019 American Transplant Congress
Low Dose Thymoglobulin Has No Disadvantages to Standard Higher Dose: A Report of the Midwest Pediatric Nephrology Consortium
I. Ashoor¹, R. Beyl², C. Gupta³, A. Jain⁴, S. Kiessling⁵, H. Patel⁶, J. Sherbotie⁷, D. J. Weaver Jr⁸, R. Zahr⁹, V. Dharnidharka¹⁰
¹LSU Health, New Orleans, LA, ²Pennington Biomedical Research Center, Baton Rouge, LA, ³Children's National Medical Center, Washington, DC, ⁴Wayne State University, Detroit, MI, ⁵University of Kentucky, Lexington, KY, ⁶Nationwide Children's Hospital, Colombus, OH, ⁷University of Utah SOM, Salt Lake City, UT, ⁸Levine Children's Hospital, Charlotte, NC, ⁹University of Tennessee, Memphis, TN, ¹⁰Washington University, St. Louis, MO
*Purpose: What is not known is whether a lower Thymoglobulin (ATG) induction dose provides safe and effective immunosuppression compared to a “standard” higher dose in…
2019 American Transplant Congress
To Each Their Own: Center-Level Variation in Tailoring Induction Immunosuppression to Kidney Transplant Recipients
S. Bae, A. Massie, J. Garonzik Wang, M. McAdams DeMarco, J. Coresh, D. Segev
Johns Hopkins University, Baltimore, MD
*Purpose: Ideally, induction immunosuppression should be selected in a personalized manner. However, there is little knowledge of what clinical factors are considered in this process…
2019 American Transplant Congress
Thymoglobulin Versus Alemtuzumab Induction in High Immunologic Risk Kidney Transplants
J. Lockridge¹, J. Pryor¹, D. Norman¹, A. Olyaei²
¹OHSU, Portland, OR, ²Pharmacy, OHSU, Portland, OR
*Purpose: The optimal induction immunosuppressive therapy to prevent kidney transplant rejection remains controversial, specifically among high immunologic risk patients. Our aim was to compare the…
2019 American Transplant Congress
Efficacy and Safety of Alemtuzumab versus Basiliximab Induction in Lung Transplantation
J. Choe, J. Au, A. Diamond, C. Ruggia-Check, S. Sehgal, F. Cordova, N. Shigemura, S. Keshavamurthy, Y. Toyoda
Temple University Hospital, Philadelphia, PA
*Purpose: Minimal literature exists regarding alemtuzumab for induction in lung transplantation but is the preferred agent at Temple University Hospital (TUH). Basiliximab is reserved for…
2018 American Transplant Congress
Basiliximab Induction in Simultaneous Liver-Kidney Transplant
C. Song, X. Luo, L. Pote, S. Strout, D. Segev, N. Desai, A. Gurakar, F. Navqi, J. Garonzik Wang.
The Johns Hopkins Hospital, Baltimore.
Rabbit anti-thymocyte globulin (rATG) is the most common induction agent in renal transplant recipients; however, induction agent selection for SLK recipients is not well described.…
2018 American Transplant Congress
Outcomes Associated with Rabbit Anti-Thymocyte Globulin Induction According to Mg/Kg of Total Body Weight in Kidney Transplant Recipients
A. Brueckner, A. Logan, L. Bowman.
Pharmacy, Tampa General Hospital, Tampa, FL.
Purpose: The optimal dosing weight used for rabbit anti-thymocyte globulin (rATG) induction therapy in transplantation continues to lack a consensus. The impact of alternative dosing…