2019 American Transplant Congress
Safety and Efficacy of Alemtuzumab Compared to Rabbit Anti-Thymocyte Globulin as Induction for Secondary Transplant after a Primary Transplant with Alemtuzumab Induction
*Purpose: Alemtuzumab and rabbit anti-thymocyte globulin (rATG) are commonly used lymphocyte depleting induction agents. Traditional thinking suggests that re-transplantation is associated with higher rejection risk,…2019 American Transplant Congress
Panel Reactive Antibody Stratification as a Guide to Induction Selection in Deceased-Donor Kidney Transplantation: Impact of Clinical Practice on Outcomes
*Purpose: We aimed to determine the outcomes associated with anti-thymocyte globulin (ATG), alemtuzumab (ALM) or interleukin-2 receptor antagonist (IL2-RA) induction in adult deceased-donor (DD) kidney…2019 American Transplant Congress
Simultaneous Pancreas and Kidney Transplant Outcomes after Induction Therapy with Thymoglobulin Compared with Alemtuzumab
*Purpose: The purpose of this study is to compare the outcomes of simultaneous pancreas and kidney transplant (SPK) recipients after two T-cell depleting induction agents:…2019 American Transplant Congress
Alemtuzumab Induction in Living Donor Renal Transplantation
The Ohio State University Wexner Medical center, Columbus, OH
*Purpose: About 15% of kidney transplant (KT) recipients receive alemtuzumab (ALM) for induction. The aim of this study was to review outcomes in living donor…2019 American Transplant Congress
Evaluation of Rabbit Antithymocyte Globulin (rATG) Dosing and Incidence of Opportunistic Viral Infections in Kidney Transplant Recipients Using Tacrolimus (TAC), Mycophenolate (MPA) and Steroid Free Maintenance Immunosuppression
The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: There is limited literature evaluating rATG dosing and incidence of infection with TAC/MPA and early steroid withdrawal. This study evaluates rATG dosing and overall…2019 American Transplant Congress
Evolution of HHV6- and CMV-Specific T Cell Functional Responses and Immune Cell Populations after Kidney Transplant
*Purpose: Human herpesvirus (HHV)-6 reactivation after solid organ or hematopoietic stem cell transplant has been associated with complications such as graft rejection and all-cause mortality.…2019 American Transplant Congress
Induction Type Does Not Influence Kidney Graft or Patient Survival in Recipients with a Previous Lung Transplant in the United States
*Purpose: Induction regimens for kidney transplant alone (KT) in lung recipients vary widely among transplant centers. We sought to examine the impact of kidney induction…2019 American Transplant Congress
Effect of Induction Therapy on Absolute CD4 Count and CD4 Percentage in HIV Positive Kidney Transplant Recipients
*Purpose: Anti-thymocyte globulin (ATG) induction causes profound and long-lasting lymphocyte depletion, with CD4+ reconstitution lagging behind other subsets. While absolute CD4 count is the preferred…2018 American Transplant Congress
Effect of Induction Therapy on CD4 Cell Count Recovery Following Renal Transplantation in HIV Positive Recipients – A Single Center Experience
Department of Transplantation, Mayo Clinic College of Medicine, Jacksonville, FL.
The feasibility, complications and outcomes of solid organ transplantation in the HIV positive population are well documented and have had excellent outcomes with a slight…2018 American Transplant Congress
Effect of rATG on Monocytic Myeloid-Derived Suppressor Cells and Its Associated Mechanisms in Kidney Transplantation Recipients
Beijing Chao-Yang Hospital, Beijing, China.
Myeloid-derived suppressor cells (MDSCs) consist of heterogeneous myeloid progenitors and precursors that was first defined in cancer patients and are characterized by a regulatory ability…
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