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Articles tagged "Induction therapy"

  • 2019 American Transplant Congress

    Impact of Induction Choice and Early Steroid Withdrawal on Outcomes in HLA Zero Mismatched Kidney Transplant Recipients

    C. Votruba1, K. Holdener1, B. Astor2, F. Aziz2, D. Mandelbrot2

    1Pharmacy, University of Wisconsin Hospitals and Clinics, Madison, WI, 2Nephrology, University of Wisconsin Hospitals and Clinics, Madison, WI

    *Purpose: Ideal induction and immunosuppression therapy for 6-antigen HLA matched deceased and living kidney transplant recipients (KTR) is not well understood.*Methods: All 6-antigen HLA matched…
  • 2019 American Transplant Congress

    Low Dose Anti-Thymocyte Globulin is Enough to Prevent Acute Cellular Rejection in Kidney Transplant

    P. W. Baron1, J. Weissman2, F. Fazeli3, C. Zuppan4, R. Villicana3, P. Wai1, L. Beeson5, M. De Vera1

    1Surgery/Transplantation Institute, Loma Linda University Health, Loma Linda, CA, 2Pharmacy, Loma Linda University Health, Loma Linda, CA, 3Transplantation Institute, Loma Linda University Health, Loma Linda, CA, 4Pathology, Loma Linda University Health, Loma Linda, CA, 5Center for Nutrition, Healthy Lifestyle and Disease Prevention/School of Public Health, Loma Linda University Health, Loma Linda, CA

    *Purpose: Rabbit anti-thymocyte globulin (rATG) cumulative dose needed to effectively and safely prevent acute cellular rejection is unknown. This study compares the efficacy of total…
  • 2019 American Transplant Congress

    Induction Immunosuppression Practices in Liver Transplantation are Variable and Predict Post-Transplant Survival

    T. Bittermann1, R. Hubbard2, J. Lewis1, D. Goldberg1

    1Gastroenterology, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: Unlike in other solid organ transplants, the benefits of induction immunosuppression prior to liver transplantation (LT) remain uncertain. The objective of this study was…
  • 2019 American Transplant Congress

    Hope in Action: A Multicenter Prospective Study of HIV to HIV Kidney Transplantation

    C. Durand1, S. Huprikar2, M. Bowring3, D. Brown1, B. Haydel4, N. Desai3, F. Naqvi1, R. Friedman-Moraco5, N. Turgeon6, V. Stosor7, J. Charette7, S. Mehta8, J. Husson9, A. Gilbert10, M. Cooper11, C. Butkus-Small12, G. Gupta13, S. Mehta14, O. Adebiyi15, P. Chin-Hong16, P. Stock17, A. Massie3, S. Florman4, D. Segev3

    1Medicine, Johns Hopkins University, Baltimore, MD, 2Medicine, Mount Sinai, New York, NY, 3Surgery, Johns Hopkins University, Baltimore, MD, 4Surgery, Mount Sinai, New York, NY, 5Medicine, Emory University, Atlanta, GA, 6Surgery, Emory University, Atlanta, GA, 7Medicine, Northwestern University, Chicago, IL, 8Medicine, University of Alabama, Birmingham, AL, 9Medicine, University of Maryland, Baltimore, MD, 10Medicine, Georgetown University, Washington DC, DC, 11Department of Surgery, Georgetown University, Washington DC, DC, 12Medicine, Cornell University, New York, NY, 13Medicine, Virginia Commonwealth University, Richmond, VA, 14Medicine, New York University, New York, NY, 15Medicine, Indiana University, Indianapolis, IN, 16Medicine, University of California at San Francisco, San Francisco, CA, 17Surgery, University of California at San Francisco, San Francisco, CA

    *Purpose:HIV+ donor to HIV+ recipient (HIV D+/R+) kidney transplantation (KT) has had success in South Africa. Expansion of this practice in the US setting of…
  • 2019 American Transplant Congress

    Early Rejection Outcomes with IL-2 vs. ATG Induction among Kidney Transplant Recipients Induction Differences with Early Steroid Withdrawal

    C. Burelli, A. Szczepanik, K. Yadav, E. Sanchez, M. Debroy, V. Humphreville, J. Rabets, A. Padiyar, N. Sarabu, A. Jittirat, A. Palanisamy, K. Chavin

    University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: Early steroid withdrawal in kidney transplant (Ktx) patients is controversial and has demonstrated an increased risk of acute rejection with similar long-term outcomes. Data…
  • 2019 American Transplant Congress

    Basiliximab vs. Low-Dose Thymoglobulin Induction Therapy in Low Risk Kidney Transplant Patients: Prospective Randomized Study in Southeastern Mexico

    G. Martinez-Mier, P. I. Moreno-Ley, L. F. Budar-Fernandez, M. T. Mendez-Lopez, D. A. Barrera-Amoros, M. De la Paz-Roman, L. A. Jimenez-López, E. G. Aguilar-Sandoval, C. A. Allende-Castellanos

    Organ Transplantation & Research, IMSS UMAE HE 14, Veracruz, Mexico

    *Purpose: Demonstrate that low dose Thymoglobulin (3 mg/kg total ) has similar efficacy (DGF, SGF, BPAR, hospitalizations, adverse events, graft loss and death) than Basiliximab…
  • 2019 American Transplant Congress

    Thymoglobulin Efficacy: The Role of Dosing on Viral Infection and Rejection in Pancreas Transplantation

    H. Sarumi, B. Johnson, S. Jackson, S. Hogan, J. Fisher, S. Riad, R. Kandaswamy, T. Pruett

    Transplant Surgery, University of Minnesota Medical Center, Minneapolis, MN

    *Purpose: While T-cell depletion therapy is standard practice for induction in pancreas transplantation, little data exists to help determine dosing and its impact on efficacy…
  • 2019 American Transplant Congress

    Predictors and Outcomes of Acute Graft-versus-Host Disease after Liver Transplant

    A. Caines1, S. Nagai2, R. Salgia1

    1Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI, 2Transplant Surgery, Henry Ford Health System, Detroit, MI

    *Purpose: Graft-versus-Host Disease (GVHD) is a rare complication of liver transplant (LT) that has an estimated incidence of 0.1%-2% per year and is associated with…
  • 2019 American Transplant Congress

    Infective Complications after Renal Transplantation – A Single Centre Experience Comparing Alemtuzumab to Basiliximab Induction

    R. Czajka, M. Welberry Smith, M. Gittus, E. Lindley, M. Vernon

    Renal Medicine, St James' University Hospital, Leeds, United Kingdom

    *Purpose: Our centre predominantly uses alemtuzumab as induction immunosuppression for renal transplantation. We examined infective complications after renal transplantation, comparing different induction, and maintenance, immunosuppression…
  • 2019 American Transplant Congress

    Type of Induction Does Not Impact Patient or Kidney Allograft Survival in Simultaneous Liver and Kidney Transplant Recipients in the United States

    S. Riad1, N. Lim2, S. Jackson3, J. Lake2

    1University of Minnesota, Minneapolis, MN, 2Medicine, University of Minnesota, Minneapolis, MN, 3Complex Care Analytics, Fairview Health Services, Minneapolis, MN

    *Purpose: Induction practices vary widely in the United States for patients undergoing simultaneous liver and kidney (SLK) transplantation. We examined the impact of induction type…
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