ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Induction therapy"

  • 2019 American Transplant Congress

    Incidence of Viral Infections in Kidney Transplant Recipients with Alemtuzumab or Rabbit Antithymocyte Globulin Induction

    A. Brueckner1, C. Truong1, E. Yanqui1, R. Baliga2, L. Bowman1

    1Tampa General Hospital, Tampa, FL, 2Florida Kidney Physicians, Tampa, FL

    *Purpose: Monoclonal antibody therapy causes profound and sustained lymphocyte depletion thus increasing the risk of viral infections. While studies exist evaluating the outcomes of alemtuzumab…
  • 2019 American Transplant Congress

    Effect of Induction Therapy on Outcomes of De Novo Renal Transplant Recipients Receiving Everolimus with Reduced-Dose Calcineurin Inhibitor: 24-Month Results from the TRANSFORM Study

    R. Oberbauer1, F. Vincenti1, O. Viklicky1, U. Huynh-Do1, D. Kim1, J. M. Cruzado1, Y. Qazi1, M. S. Kim1, P. Narvekar2, M. P. Hernandez Gutierrez2, P. Bernhardt2, D. Kuypers1

    1TRANSFORM Study Group, Basel, Switzerland, 2Novartis Pharma AG, Basel, Switzerland

    *Purpose: To assess the effect of induction therapy on efficacy and safety outcomes of de novo renal transplant recipients (RTxR) receiving everolimus with reduced calcineurin…
  • 2019 American Transplant Congress

    Living Donor Renal Transplantation without Any Induction Immunosuppression in Spousal Donors – Single Center Experience

    R. Bhat, F. Aziz, I. N. Abubecker, S. Narayanan, B. Hafeeque

    Nephrology & Transplantation, Malabar Instiute of Medical Sciences, Calicut, India

    *Purpose: Renal transplantation in India is primarily driven by living related donation; parents and spouse constitute 70% of donors in India. Some centres use induction…
  • 2019 American Transplant Congress

    A Prospective, Randomized, Multicenter Trial of Bela-Based CNI Free and Steroid Withdrawal Immunosuppression: Best Trial Two Year Characterization of Rejection and Renal Function

    A. Wiseman1, A. R. Shields2, R. R. Alloway2, D. Kaufman3, J. P. Leone4, A. J. Matas5, P. West-Thielke6, J. Lipscomb2, E. King2, E. S. Woodle for the BEST Study Group2

    1University of Colorado School of Medicine, Denver, CO, 2University of Cincinnati, Cincinnati, OH, 3University of Wisconsin, Madison, WI, 4Tampa General, Tampa, FL, 5University of Minnesota, Minneapolis, MN, 6University of Illinois, Chicago, Chicago, IL

    *Purpose: The BEST Trial (Belatacept-based Early Steroid Withdrawal Trial) was designed to compare two BELA-based early steroid withdrawal (ESW) regimens with a TAC-based ESW regimen…
  • 2019 American Transplant Congress

    Effect of ATG on Monocytic Myeloid-Derived Suppressor Cells and Its Associated Mechanisms in Kidney Transplantation Recipients

    Y. Jiang, X. Zhang

    Beijing Chao-yang Hospital, Beijing, China

    *Purpose: Myeloid-derived suppressor cells (MDSCs) consist of heterogeneous myeloid progenitors and precursors that was first defined in cancer patients and are characterized by a immunoregulatory…
  • 2019 American Transplant Congress

    Induction with Thymoglobulin in DCD Kidneys. Dose Effect and Predictors of Outcome

    A. Asderakis, T. Sabah, A. Jones, E. Ablorsu, L. Szabó, R. Chavez

    Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom

    *Purpose: Thymoglobulin (ATG) is used only in few UK centres as induction. We have previously shown good results with ATG for pancreas transplants. The aim…
  • 2019 American Transplant Congress

    Low Dose Thymoglobulin Has No Disadvantages to Standard Higher Dose: A Report of the Midwest Pediatric Nephrology Consortium

    I. Ashoor1, R. Beyl2, C. Gupta3, A. Jain4, S. Kiessling5, H. Patel6, J. Sherbotie7, D. J. Weaver Jr8, R. Zahr9, V. Dharnidharka10

    1LSU Health, New Orleans, LA, 2Pennington Biomedical Research Center, Baton Rouge, LA, 3Children's National Medical Center, Washington, DC, 4Wayne State University, Detroit, MI, 5University of Kentucky, Lexington, KY, 6Nationwide Children's Hospital, Colombus, OH, 7University of Utah SOM, Salt Lake City, UT, 8Levine Children's Hospital, Charlotte, NC, 9University of Tennessee, Memphis, TN, 10Washington University, St. Louis, MO

    *Purpose: What is not known is whether a lower Thymoglobulin (ATG) induction dose provides safe and effective immunosuppression compared to a “standard” higher dose in…
  • 2019 American Transplant Congress

    To Each Their Own: Center-Level Variation in Tailoring Induction Immunosuppression to Kidney Transplant Recipients

    S. Bae, A. Massie, J. Garonzik Wang, M. McAdams DeMarco, J. Coresh, D. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Ideally, induction immunosuppression should be selected in a personalized manner. However, there is little knowledge of what clinical factors are considered in this process…
  • 2019 American Transplant Congress

    Thymoglobulin Versus Alemtuzumab Induction in High Immunologic Risk Kidney Transplants

    J. Lockridge1, J. Pryor1, D. Norman1, A. Olyaei2

    1OHSU, Portland, OR, 2Pharmacy, OHSU, Portland, OR

    *Purpose: The optimal induction immunosuppressive therapy to prevent kidney transplant rejection remains controversial, specifically among high immunologic risk patients. Our aim was to compare the…
  • 2019 American Transplant Congress

    Efficacy and Safety of Alemtuzumab versus Basiliximab Induction in Lung Transplantation

    J. Choe, J. Au, A. Diamond, C. Ruggia-Check, S. Sehgal, F. Cordova, N. Shigemura, S. Keshavamurthy, Y. Toyoda

    Temple University Hospital, Philadelphia, PA

    *Purpose: Minimal literature exists regarding alemtuzumab for induction in lung transplantation but is the preferred agent at Temple University Hospital (TUH). Basiliximab is reserved for…
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