2017 American Transplant Congress
Impact of Bariatric Surgery on Risk of Organ Rejection Among Solid Organ Transplant Recipients.
Medicine, Northwestern University, Chicago, IL; Surgery, Northwestern University, Chicago, IL
Background: Obesity is a common condition that contributes to organ failure. Bariatric surgery is an effective surgical therapy for obesity and has been performed both…2017 American Transplant Congress
Belatacept Conversion for Calcineurin Inhibitor (CNI) Toxicity: Our First 100 Patients.
Intro: CNIs improve kidney transplant (KT) survival, but have significant toxicities, including graft dysfunction (GD), neurotoxicity (NT), or thrombotic microangiopathy (TMA). Belatacept is an alternative…2017 American Transplant Congress
Blockade of Tim-3 and PD-1 Reverses Dysfunctions of Tumor Infiltrating Lymphocytes in HBV Related Hepatocellular Carcinoma.
The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
The immunosuppression of tumor infiltrating lymphocytes (TILs) is associated with rapid progress of hepatitis B virus related hepatocellular carcinoma (HBV-HCC). The inhibition molecules of T…2017 American Transplant Congress
Allograft Cytokine Activation and Elevated Tissue Indoleamine 2,3-Dioxygenase Gene and Protein Expression in Rejecting Pig Transplants.
Viral delivery of the indoleamine 2,3-dioxygenase (IDO) transgene results in transprotein synthesis and mitigates rejection in rodent kidney transplants (J Gene Med 13:373); but in…2017 American Transplant Congress
Understanding the Role of Induction Agents in Older versus Younger Kidney Transplant Recipients.
Johns Hopkins University, Baltimore, MD
Background: There has been an increase in the number of older (over 65) KT recipients. Aging-related changes such as differences in immune senescence may influence…2017 American Transplant Congress
Photopheresis for Recalcitrant Rejection After Heart Transplantation: Worthwhile?
Cedars-Sinai Heart Institute, Los Angeles
Background: Rejection is leading cause of mortality after heart transplantation (HTx). While the rates of rejection have declined over the past few decades from improvement…2017 American Transplant Congress
Soluble Fibrinogen-Like Protein 2 Regulates Differentiation and Enhances Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Allograft Immunity.
Urology, Zhongshan Hospital, Fudan University, Shanghai, China
Soluble fibrinogen-like protein 2 (sFGL2) is a novel immunoregulatory molecule, secreted mainly by regulatory T cells. CD11b+ Gr1+ myeloid-derived suppressor cells (MDSCs) are an important…2017 American Transplant Congress
Pre Transplant Donor Specific Antibodies and Clinical Outcomes in Kidney Transplant Recipient on Steroid Free Maintenance Immunosupression Regimen.
Background: The clinical relevance of pre transplant donor specific antibodies has been reported in few clinical studies with respect to its effect on the risk…2017 American Transplant Congress
Effect of Everolimus on the Cardiac Function in Kidney Transplant Recipients.
PURPOSE: In this study, we evaluated the effect of everolimus (EVR), one of the mammalian targets of rapamycin on cardiac function in kidney transplant recipients.METHODS:We…2017 American Transplant Congress
mTOR Inhibitor and Low-Dose Tacrolimus in Pediatric Kidney Transplant (PKT): 9-Years Data of a Bi-Therapy Treatment.
Pediatric Nephrology, Hosptal Vall d´Hebron, Barcelona, Spain
INTRODUCTIONNephrotoxicity , serious infectious, or malignancy risk , curtails tacrolimus use in PKT . However, based on potential antiviral and antitumoral actions of mTOR inhibitor…
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