2018 American Transplant Congress
Lack of Efficacy of Eculizumab for Prevention of Delayed Graft Function (DGF) in Deceased Donor Kidney Transplant Recipients
DGF portends poor short- and long-term renal function, increases cost, and may reduce graft survival. We studied the safety/efficacy of eculizumab (ECU), a C5 convertase…2018 American Transplant Congress
Digital Health Education for the Pediatric Solid Organ Transplant Population
Background: Self-management and adherence are key factors that influence post transplant graft survival. Education after solid organ transplant plays an important role in providing patients…2018 American Transplant Congress
Early Steroid Withdrawal or Tacrolimus Minimization versus Standard Immunosuppression in Renal Transplant Recipients: The Allegro Trial
BackgroundCurrent immunosuppressive regimen in most renal transplant recipients (RTR) combines basiliximab induction with tacrolimus, mycophenolic acid and prednisolone maintenance therapy. Reduction of immunosuppression by withdrawal…2018 American Transplant Congress
Evaluation of Multiple Linear Regression Limited Sampling Strategies for Enteric-Coated Mycophenolate Sodium in Adult Kidney Transplant Recipients
Background: Although multiple linear regression-based limited sampling strategies (LSS) have been published for enteric-coated mycophenolate sodium none have been evaluated for prediction of subsequent mycophenolic…2018 American Transplant Congress
mTOR Inhibitor Based Immunosuppression Regimens Are Not Associated with Lower Risk for BK Infection
Introduction: BK virus continues to be a significant post-transplant complication with increasing incidence in the current era of potent immunosuppression. Mammalian target of rapamycin inhibitors…2018 American Transplant Congress
Evaluation of Clinical and Safety Outcomes Following Uncontrolled Tacrolimus Conversion in Adult Transplant Recipients
Background: Long-term studies with control groups are required to assess tacrolimus (TAC) conversion. The purpose of this study was to compare clinical and safety outcomes…2018 American Transplant Congress
Predicting Early and Late eGFR Variability in Kidney Transplant Recipients
Department of Medicine and Department of Surgery, MUSC, Charleston, SC.
Introduction: eGFR variability is a known risk factor for graft loss. It is unclear what modifiable factors are significantly associated with this variability and if…2018 American Transplant Congress
Human Thrombomodulin Expression on Genetically Modified Donor Pigs is Required to Maintain the Anti-Coagulation Profile
Introduction: Coagulation dysregulation is major limitation for xenotransplantation but it is resolved to some extent by making genetically engineered (GE) pigs, which express complement inhibitors…2018 American Transplant Congress
The Influence of a Conversion to Sirolimus-Based Immunosuppression on Non-Melanomatous Skin Cancer Incidence in Kidney Transplant Recipients over Long Term Follow Up
Background: The CONVERT trial found a reduced incidence of malignancy amongst renal transplant recipients over 2 years of follow up with a conversion from calcineurin…2018 American Transplant Congress
Improved Long-Term Outcomes of Pancreas Transplantation: Analysis of Allograft Half-Lives and Predictive Demographic Factors
Department of Surgery Division of Transplantation, University of Minessota, Minneapolis, MN.
In contrast to other solid organ transplants, the characteristics of long term surviving pancreas transplants have not been well described. Our objective was to measure…
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