ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2019 American Transplant Congress

    The Effect Of Tacrolimus Trough Variability On Kidney Transplant Outcomes

    S. Heeney1, K. R. Szempruch1, R. Lee1, A. Mintz2, P. Serrano1, R. Detwiler1, C. Doligalski1

    1University of North Carolina Medical Center, Chapel Hill, NC, 2University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC

    *Purpose: High variability in tacrolimus as assessed by tacrolimus coefficient of variability (TCV) in trough levels of kidney transplant recipients (KTRs) has been associated with…
  • 2019 American Transplant Congress

    Conversion to Belatacept in Kidney Transplant Recipients with Systemic Lupus Erythematosus

    I. Carrión Barberà, M. C. Fajardo, D. Tsapepas, J. Gartshteyn, A. Askanase, H. E. Fernandez

    Columbia University MC, New York, NY

    *Purpose: Lupus nephritis (LN) results in the need for renal replacement therapy (RRT) in 10-30% of LN pts and 30% receive a kidney transplant (KT).…
  • 2019 American Transplant Congress

    Patient Reported Side Effects Associated with Reduced Quality of Life after Living Donor Kidney Transplant

    J. Peipert, J. C. Caicedo-Ramirez, K. Ensor, J. Friedewald, M. Abecassis, D. Cella, D. Ladner, Z. Butt

    Northwestern University, Chicago, IL

    *Purpose: As living donor kidney transplant (LDKT) graft and patient survival approaches 100%, the focus of care turns to patient reported outcome measures such as…
  • 2019 American Transplant Congress

    Comparison of Tacrolimus or Cyclosporine Combined with Methotrexate for Graft versus Host Disease Prophylaxis after Allogeneic Hematopoietic Cell Transplantation: A Meta-Analysis

    M. Chen, B. Huang, Y. Zhang, W. Ju, X. He

    Transplant Center, Sun Yat-sen University, Guangzhou, China

    *Purpose: After patients received hematopoietic stem cell transplantation (HSCT) ,both cyclosporine (CsA) and tacrolimus (TAC) in combination with methotrexate (MTX) have been recommended as standard…
  • 2019 American Transplant Congress

    Efficacy and Safety of Everolimus in Pediatric Renal Transplantation

    T. Sandes-Freitas1, B. Pantoja2, M. Custódio2, A. Goersch Silva3, R. Costa2, M. Sales3, R. Esmeraldo3

    1Hospital Geral de Fortaleza / Federal University of Ceara, Fortaleza, Brazil, 2Federal University of Ceará, Fortaleza, Brazil, 3Hospital Geral de Fortaleza, Fortaleza, Brazil

    *Purpose: There are scarce evidence on the efficacy and safety of everolimus (EVR)-based regimens in pediatric kidney transplantation (KT).*Methods: This single center retrospective cohort analyzed…
  • 2019 American Transplant Congress

    Induction Immunosuppression Practices in Liver Transplantation are Variable and Predict Post-Transplant Survival

    T. Bittermann1, R. Hubbard2, J. Lewis1, D. Goldberg1

    1Gastroenterology, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: Unlike in other solid organ transplants, the benefits of induction immunosuppression prior to liver transplantation (LT) remain uncertain. The objective of this study was…
  • 2019 American Transplant Congress

    Determining the Role of Insurance Coverage at the Time of Renal Transplantation as a Predictor of Medication Misadventure

    D. Wilkerson, P. Klem

    Pharmacy, University of Colorado Skaggs School of Pharmacy, Aurora, CO

    *Purpose: To determine if patients who receive financial assistance through the American Kidney Fund (AKF) for health care premiums at the time of transplant are…
  • 2018 American Transplant Congress

    Belatacept Maintenance Immunosuppression Use and Outcomes in the Real-World Clinical Setting Using OPTN/UNOS Kidney Transplant Registry

    S. Sanoff,1 K. Ravindra,1 W. Irish.1,2

    1Duke University Medical Center, Durham, NC; 2CTI Consulting, Raleigh, NC.

    Introduction:Belatacept (BEL) was FDA approved for Kidney Transplantation (KTx) June 2011. It has largely been evaluated in two controlled trials (N Engl J Med 2016;374:333-43).…
  • 2018 American Transplant Congress

    Validation of an Integrative and Dynamic Prognostic Score for Response to Therapy in Solid Organ Transplants

    A. Loupy, O. Aubert, D. Viglietti, C. Legendre, D. Glotz, C. Lefaucheur.

    Paris Translational Center for Organ Transplantation, Paris, France.

    Drug development in transplantation has diminished due to the lack of suitable endpoints for predicting graft failure. We sought to validate the performance of an…
  • 2018 American Transplant Congress

    Cost Impacts of Alternative Kidney Transplant Immunosuppression: A National Cohort Study

    K. Lentine,1 D. Axelrod,2 V. Dharnidharka,3 H. Xiao,1 D. Brennan,4 D. Segev,4 H. Randall,1 R. Ouseph,1 A. Naik,5 N. Lam,6 T. Alhamad,3 B. Kasiske,7 G. Hess,8 M. Schnitzler.1

    1Saint Louis Univ, St. Louis; 2Lahey Clinic, Burlington; 3Washington Univ, St. Louis; 4Johns Hopkins, Baltimore; 5Univ Michigan, Ann Arbor; 6Univ Alberta, Edmonton, Canada; 7Hennepin County, Minneapolis; 8Symphony Health, Conshohocken.

    Economic outcomes are increasingly considered along with clinical efficacy to guide choice of alternative therapies. We examined the cost impact of kidney transplant (KTx) induction…
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