ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2019 American Transplant Congress

    Urinary Biomarkers of Kidney Injury in Liver Transplant Recipients with Calcineurin Inhibitors Based Immunosuppression

    D. Maluf1, V. Bontha1, A. Bajwa2, A. Abdelaal1, C. Koo1, J. D. Eason2, V. Mas2

    1UTHSC, Memphis, TN, 2Transplant Institute, Memphis, TN

    *Purpose: Renal dysfunction post solid organ transplantation is common and associated with several risk factors. Messenger RNA encoding for genes expressed along the nephron and…
  • 2019 American Transplant Congress

    A Cluster of Late Onset of Pneumocystis jirovecii Pneumonia (PJP) in Renal Transplant Patients: First Cluster Report from Saudi Arabia

    Y. Aljishi, M. AlBugumi, A. Abadi, A. AlJanobi, M. Al Lawiam, N. Alzawad, M. Al Sardi, Z. AlMaa, H. Al-Ramadan, J. Kabanja, N. Rayyan, k. Beleed-Akkari

    King Fahad specialist hospital - Dammam, Dammam, Saudi Arabia

    *Purpose: Pneumocystis jiroveci pneumonia (PJP) is a serious opportunistic infection that can be associated with severe pulmonary involvement in transplant population. Post-transplant protocol at our…
  • 2019 American Transplant Congress

    Risk Factors for Sensitization in the Failing Allograft: A Multi-Center Experience

    M. Lubetzky1, O. Mohammed2, N. Hauser1, R. Friedlander1, V. Sharma1, A. Colovai2, T. Muthukumar1, J. Lee1, E. Akalin2, D. Dadhania1

    1Division of Nephrology, Weil Cornell, New York, NY, 2Division of Nephrology, Montefiore Medical Center, New York, NY

    *Purpose: Sensitization is frequent after an allograft fails and makes re-transplant difficult for many patients.*Methods: We performed a cross-sectional chart review of patients who were…
  • 2019 American Transplant Congress

    Impact of Granulocyte Colony Stimulating Factor on Clinical Outcomes in Kidney Transplant Recipients with Neutropenia

    H. Yao1, A. Alam2, R. Sapir-Pichhadze2, D. D’Arienzo3, D. Baran2, S. Sandal2, M. Cantarovich2

    1Critical Care Medicine, McGill University Health Center, Montreal, QC, Canada, 2Nephrology and Multi-Organ Transplant Program, McGill University Health Center, Montreal, QC, Canada, 3Medicine, McGill University Health Center, Montreal, QC, Canada

    *Purpose: Neutropenia, defined as an absolute neutrophil count (ANC)
  • 2019 American Transplant Congress

    Safety and Efficacy of Peri-Operative Sublingual Tacrolimus in Pancreas Transplant as Compared to Oral Tacrolimus

    N. Patel, C. Perez, D. Taber, V. Kalbavi, V. Rohan

    MUSC, Charleston, SC

    *Purpose: Early post-transplant, use of oral or enteral medications in pancreas transplant (PTX) is difficult due to NG tubes put to suction. The use of…
  • 2019 American Transplant Congress

    Development and Validation of a Capillary Blood Mitra-Based Assay for the Quantitative Determination of Advagraf® Concentrations in Transplant Patients

    N. Undre1, I. Dawson2, V. Aluvihare3, N. Kamar4, F. Saliba5, N. Torpey6, S. Anaokar7, G. Kazeem1

    1Astellas Pharma Europe Ltd, Chertsey, United Kingdom, 2Covance Laboratories, Harrogate, United Kingdom, 3Kings College Hospital, London, United Kingdom, 4CHU Rangueil, Toulouse, France, 5Hôpital Paul-Brousse, Villejuif, France, 6Addenbrookes Hospital, Cambridge, United Kingdom, 7Astellas Pharma Europe Ltd, Surrey, United Kingdom

    *Purpose: Therapeutic drug monitoring of tacrolimus (TAC) requires venepuncture blood samples taken by specialists, requiring patients to attend an outpatient clinic; this can be inconvenient…
  • 2019 American Transplant Congress

    Technology Triggered Adherence Intervention – Preliminary Findings

    T. E. Kaiser1, N. S. Ejaz1, S. Tremblay1, N. J. Parrish2, J. Benavides2, B. Rehe2, A. Govil1, E. S. Woodle1, R. R. Alloway1

    1University of Cincinnati, Cincinnati, OH, 2UC Health, Cincinnati, OH

    *Purpose: Medication non-adherence (M-NA) after renal transplant (RT) increases the risk of graft failure. We conducted a prospective, randomized, single center trial to evaluate 3…
  • 2019 American Transplant Congress

    Resolution of Hyperglycemia Following Islet Allograft Transplantation in Non-Immunosuppressed Mice

    J. Ge1, K. Lee1, C. Yang1, R. White2, I. Rosales2, P. Russell1, C. Rickert1, J. Markmann1, J. Madsen1, R. Colvin2, A. Alessandrini1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Pathology, Massachusetts General Hospital, Boston, MA

    *Purpose: Kidney allografts are naturally tolerogenic in mice. Certain mouse strain combinations develop tolerance of kidney allografts across full MHC incompatibilities without immunosuppression (e.g. DBA/2…
  • 2019 American Transplant Congress

    Age-Related Effects on Thymic Output and Homeostatic T Cell Expansion Following Depletional Induction

    H. Xu, H. Lee, A. Kirk

    Surgery, Duke University, Durham, NC

    *Purpose: Alemtuzumab induction leads to profound T cell depletion followed by a prolonged period of repopulation. Repopulation is thought to be influenced both by thymic…
  • 2019 American Transplant Congress

    Race-Sex Effects on Immune Response Potential during Tacrolimus Minimization Therapy in Stable Renal Allograft Recipients

    K. Tornatore1, K. Attwood2, R. Venuto3, H. Minderman4

    1University at Buffalo; School of Pharmacy, Buffalo, NY, 2Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 3University at Buffalo; School of Medicine: Nephrology, Buffalo, NY, 4Flow & Image Cytometry, Roswell Park Comprehensive Cancer Center, Buffalo, NY

    *Purpose: African American renal transplant recipients (RTR) exhibit more immunoreactivity to allografts which may contribute to chronic rejection. This study investigated race-sex influences on ex…
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