ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2019 American Transplant Congress

    Impact Of Selective Cd28 Blockade On Protective Immunity To A Murine Epstein-Barr Virus Homolog

    R. L. Crepeau, J. A. Elengickal, M. L. Ford

    Surgery, Emory University, ATLANTA, GA

    *Purpose: CTLA-4Ig blocks CD80/CD86, the ligands for both CD28 and CTLA-4. Thus, in addition to the intended effect of blocking CD28-mediated costimulation, CTLA4-Ig also has…
  • 2019 American Transplant Congress

    Infectious Complications in Tocilizumab-Treated Kidney Transplant Recipients

    S. Sethi, A. Peng, R. Najjar, A. Vo, S. Jordan, E. Huang

    Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: Tocilizumab blocks IL-6 signaling, inhibiting maturation of B cells to plasma cells and antibody production. We have used tocilizumab since 2012 to treat kidney…
  • 2019 American Transplant Congress

    Development of a Pharmacy Collaborative Practice Agreement to Improve Efficiency and Management of Prescribing in a Renal Transplant Clinic

    R. Chelewski1, K. Johnson1, A. Zuckerman2, J. DeClercq3, L. Choi3, M. Peter2, A. J. Langone4

    1Vanderbilt Specialty Pharmacy Services, Vanderbilt Univ Medical Ctr, Nashville, TN, 2Department of Pharmacy, Vanderbilt Univ Medical Ctr, Nashville, TN, 3Department of Biostatistics, Vanderbilt Univ Medical Ctr, Nashville, TN, 4Division of Nephrology, Vanderbilt Univ Medical Ctr, Nashville, TN

    *Purpose: This study describes the development of a Collaborative Pharmacy Practice Agreement (CPPA) between transplant pharmacists and physicians and assesses change in prescription volume and…
  • 2019 American Transplant Congress

    The Effect Of Tacrolimus Trough Variability On Kidney Transplant Outcomes

    S. Heeney1, K. R. Szempruch1, R. Lee1, A. Mintz2, P. Serrano1, R. Detwiler1, C. Doligalski1

    1University of North Carolina Medical Center, Chapel Hill, NC, 2University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC

    *Purpose: High variability in tacrolimus as assessed by tacrolimus coefficient of variability (TCV) in trough levels of kidney transplant recipients (KTRs) has been associated with…
  • 2019 American Transplant Congress

    Conversion to Belatacept in Kidney Transplant Recipients with Systemic Lupus Erythematosus

    I. Carrión Barberà, M. C. Fajardo, D. Tsapepas, J. Gartshteyn, A. Askanase, H. E. Fernandez

    Columbia University MC, New York, NY

    *Purpose: Lupus nephritis (LN) results in the need for renal replacement therapy (RRT) in 10-30% of LN pts and 30% receive a kidney transplant (KT).…
  • 2019 American Transplant Congress

    Patient Reported Side Effects Associated with Reduced Quality of Life after Living Donor Kidney Transplant

    J. Peipert, J. C. Caicedo-Ramirez, K. Ensor, J. Friedewald, M. Abecassis, D. Cella, D. Ladner, Z. Butt

    Northwestern University, Chicago, IL

    *Purpose: As living donor kidney transplant (LDKT) graft and patient survival approaches 100%, the focus of care turns to patient reported outcome measures such as…
  • 2019 American Transplant Congress

    Comparison of Tacrolimus or Cyclosporine Combined with Methotrexate for Graft versus Host Disease Prophylaxis after Allogeneic Hematopoietic Cell Transplantation: A Meta-Analysis

    M. Chen, B. Huang, Y. Zhang, W. Ju, X. He

    Transplant Center, Sun Yat-sen University, Guangzhou, China

    *Purpose: After patients received hematopoietic stem cell transplantation (HSCT) ,both cyclosporine (CsA) and tacrolimus (TAC) in combination with methotrexate (MTX) have been recommended as standard…
  • 2019 American Transplant Congress

    Efficacy and Safety of Everolimus in Pediatric Renal Transplantation

    T. Sandes-Freitas1, B. Pantoja2, M. Custódio2, A. Goersch Silva3, R. Costa2, M. Sales3, R. Esmeraldo3

    1Hospital Geral de Fortaleza / Federal University of Ceara, Fortaleza, Brazil, 2Federal University of Ceará, Fortaleza, Brazil, 3Hospital Geral de Fortaleza, Fortaleza, Brazil

    *Purpose: There are scarce evidence on the efficacy and safety of everolimus (EVR)-based regimens in pediatric kidney transplantation (KT).*Methods: This single center retrospective cohort analyzed…
  • 2019 American Transplant Congress

    Induction Immunosuppression Practices in Liver Transplantation are Variable and Predict Post-Transplant Survival

    T. Bittermann1, R. Hubbard2, J. Lewis1, D. Goldberg1

    1Gastroenterology, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: Unlike in other solid organ transplants, the benefits of induction immunosuppression prior to liver transplantation (LT) remain uncertain. The objective of this study was…
  • 2019 American Transplant Congress

    Determining the Role of Insurance Coverage at the Time of Renal Transplantation as a Predictor of Medication Misadventure

    D. Wilkerson, P. Klem

    Pharmacy, University of Colorado Skaggs School of Pharmacy, Aurora, CO

    *Purpose: To determine if patients who receive financial assistance through the American Kidney Fund (AKF) for health care premiums at the time of transplant are…
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