2022 American Transplant Congress
Frequency of Cervical Cancer Screening in Solid Organ Transplant Recipients
*Purpose: Human papillomavirus-related anogenital malignancies disproportionately affect solid organ transplant recipients (SOTR) compared to the general population. Proposed cervical Pap testing intervals for SOTR differ…2022 American Transplant Congress
Long-Term Rejection Free Renal Allograft Survival with Fc-Modified Anti-cd154 Antibody Monotherapy in Nonhuman Primates
MGH Center for Transplantation Sciences, Boston, MA
*Purpose: Belatacept is currently the only FDA approved costimulatory blockade (CB) used as an alternative to calcineurin inhibitors in kidney transplantation. However, it has been…2022 American Transplant Congress
Impact Of Antifungal Prophylaxis Discontinuation On Immunosuppression In Lung Transplant Recipients
Pharmacy, Cleveland Clinic, Cleveland, OH
*Purpose: The purpose of this study is to characterize the impact of antifungal discontinuation on immunosuppressant levels and incidence of acute rejection and fungal infections…2022 American Transplant Congress
Associations of Immunosuppression Regimen with Fracture Risk After Kidney Transplant in High-Risk Populations: Identifying Targets for Risk-Reduction
*Purpose: Disorders of bone and mineral metabolism frequently develop with advanced kidney disease, may be exacerbated by immunosuppression (ISx) after kidney transplant (KTx), and may…2022 American Transplant Congress
Suppressive Effect of De Novo Everolimus on Primary Cytomegalovirus Infection in Kidney Transplant Recipient
*Purpose: It has been reported that everolimus (EVR) administration reduces the incidence of cytomegalovirus (CMV) infection, but clinical outcome in CMV-seronegative recipients with EVR-based regimen…2022 American Transplant Congress
Outcomes in Lung Transplant Recipients Switched from Tacrolimus to Cyclosporine Due to Hyperammonemia Early Post-Transplantation
Loyola University Medical Center, Chicago, IL
*Purpose: Assess the impact of switching from tacrolimus to cyclosporine due to hyperammonemia on outcomes at 1-year post-lung transplant.*Methods: A retrospective review of lung transplant…2022 American Transplant Congress
Validation of the iBox Surrogate End Point in CNI Free, Belatacept Treated Patients (BENEFIT & BENEFIT-EXT)
*Purpose: The iBox is a prognostication system for long-term kidney allograft survival, developed with mostly patients under a CNI based immunosuppression. Patients treated with a…2022 American Transplant Congress
A Novel IL-2 Mutein Selectively Expands Regulatory T Cells and Prolongs Skin Graft Survival
*Purpose: Promoting immune regulation through expansion of regulatory T cell (Treg) may allow immunosuppression minimization and improve long-term graft outcomes. Low-dose IL-2 is known to…2022 American Transplant Congress
Pre-Transplant Vaccine Induced SARS-CoV-2 Antibodies Decrease Following Induction Therapy for Kidney Transplantation
*Purpose: Kidney transplant recipients (KT) and wait-listed individuals exhibit an impaired response to vaccinations. There is currently no data on the impact of induction immunosuppression…2022 American Transplant Congress
The Role Of Gut Microbiome In Optimum Dose Selection Of Tacrolimus For Kidney Transplant Recipients
1George Mason University, Arlington, VA, 2George Washington University Hospital, Washington, DC
*Purpose: This study aims to validate and apply a personalized optimal dose selection model for Tacrolimus (Tac) for kidney transplant recipients at the George Washington…
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