Articles tagged "Immunosuppression"

2020 American Transplant Congress
Induction Immunosuppression in Primary Pediatric Liver Transplant Recipients
T. Shaker¹, K. Ramanathan¹, S. Riad², D. Vock³, S. Chinnakotla¹
¹Surgery, Division of Transplantation, University of Minnesota, Minneapolis, MN, ²Division of Renal Diseases and Hypertension, University of Minnesota, Minneapolis, MN, ³Biostatistics, University of Minnesota, Minneapolis, MN
*Purpose: Induction immunosuppression for pediatric liver transplants varies widely among centers. We sought to evaluate the impact of different induction regimens on patient and graft…
2020 American Transplant Congress
Comparison of 4 vs 14 Days Early Steroid Withdrawal in Kidney Transplant Recipients
O. Adebiyi, J. Chen, B. Brady, S. Mietz, T. Taber, D. Mishler, M. Yaqub, W. Goggins, A. Sharfuddin
Indiana University, Indianapolis, IN
*Purpose: The optimal duration, as well as the dose of the initial steroid use, is not known as it varies widely among institutions that have…
2020 American Transplant Congress
A Two-Step Cell-Based Assay Predicts Immunosuppression-Related Adverse Events in Kidney Transplant Recipients
F. Bouchard-Boivin, O. Désy, S. Béland, S. De Serres
Transplantation Unit, Renal Division, Medecine Department, Laval University, Québec, QC, Canada
*Purpose: No clinical tool is available to dynamically access immunosuppression status, which results in serious, often life-threatening adverse effects of immunosuppressants. We recently validated that…
2020 American Transplant Congress
A Single Centre Experience of Conversion from Immediate Release Tacrolimus (IR-tac) to Extended Release Envarsus
S. Chong¹, E. Kent², C. Beligaswatta², P. Gudka², C. Magee², M. Harber², R. Motallebzadeh¹, G. Jones²
¹Centre for Transplantation, Department of Renal Medicine, University College London & Royal Free London NHS Foundation Trust, London, United Kingdom, ²Department of Renal Medicine, University College London & Royal Free London NHS Foundation Trust, London, United Kingdom
*Purpose: IR-Tac is first line maintenance immunosuppression in kidney transplant recipients. Its rapid absorption of 1-2 hours can lead to peak levels (Tmax ) within…
2020 American Transplant Congress
The Importance of Annual Medicare Part D Plan Evaluation in Heart Transplantation
L. M. Lourenco
Pharmacy Services, University of Chicago Medicine, Chicago, IL
*Purpose: The Medicare open enrollment period is from Oct 15 to Dec 7, annually. The purpose of this project was to objectively measure the benefit…
2020 American Transplant Congress
Efficacy and Possible Risk of De Novo Use of Everolimus for Primary Kidney Transplantation
S. Narumi¹, Y. Watarai¹, N. Goto², T. Hiramtsu¹, M. Okada¹, K. Futamura², T. Tomosugi¹, A. Kanda², T. Kobayashi³
¹Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya City, Aichi Prefecture, Japan, ²Transplant Nephrology, Nagoya Daini Red Cross Hospital, Nagoya City, Aichi Prefecture, Japan, ³Transplant Surgery, Aichi Medical University School of Medicine, Nagakute City, Aichi Prefecture, Japan
*Purpose: Transplant outcome and protocol stay rate of everolimus were investigated to clarify efficacy and risk of everolimus based regimens at a single institute.*Methods: During…
2020 American Transplant Congress
Case Series of Belatacept for Calcineurin Inhibitor Sparing after Lung Transplantation
H. Patel, C. R. Ensor, R. D. Davis, L. Bogar, D. Colella, M. Kildea, J. Kim, A. Satterthwaite, D. Ventura, C. Gries
AdventHealth, Orlando, FL
*Purpose: Belatacept is a recombinant soluble fusion protein which selectively blocks T-cell co-stimulation. It received initial FDA approval for prophylaxis of organ rejection in Epstein-Barr…
2020 American Transplant Congress
The Role of mTOR Inhibitors on Cardiovascular Aging in Renal Transplanted Patients with Chronic Graft Dysfunction
G. Castellano¹, B. Infante¹, P. Pontrelli¹, R. Franzin¹, F. Rascio¹, C. Prisciandaro², L. Gesualdo¹, N. Coviello³, G. Grandaliano³, G. Stallone³
¹Emergency and Organ Transplantation, University of Bari, Bari, Italy, ²University of Foggia, Foggia, Italy, ³Emergency and Organ Transplantation, University of Foggia, Foggia, Italy
*Purpose: Chronic Kidney Disease (CKD) is strongly associated with increased circulatory complications that can lead to accelerated cardiovascular aging. During CKD, persistent oxidative stress triggered…
2020 American Transplant Congress
Efficacy of Photobiomodulation Therapy Combined with Short-Term Immunosuppressants Prolonged Allotransplant Survival in a Rodent Hind-Limb Model
Y. Kuo¹, C. Chen², R. Chen², Y. Li²
¹Division of Plastic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ²Division of Plastic Surgery, Department of Surgery,, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
*Purpose: Photobiomodulation has been applied for accelerating the skeletal muscle repair process. Our formal study demonstrated vitamin D could be involved in allograft survival and…
2020 American Transplant Congress
Treg Lymphotoxin Signals Promote Cancer Metastatic Migration: Mechanisms for Treg-Cancer Interaction
W. Piao¹, R. Oakes², C. Paluskievicz¹, Y. Xiong¹, L. Li¹, V. Saxena¹, M. WillsonShirkey¹, C. Jewell², J. Bromberg¹
¹Surgery, U of Maryland, Baltimore, MD, ²U of Maryland, College Park, MD
*Purpose: Immune suppressive therapy can be complicated by malignancy. Regulatory T cells (Treg) control immune tolerance for graft survival but cause to immune suppression in…