2020 American Transplant Congress
Daily Immunosuppression to Combat Compliance in Adolescent Kidney Transplant
1Surgery, Stanford University, Stanford, CA, 2Pediatrics, Stanford University, Stanford, CA
*Purpose: Medication compliance remains a persistent, multifactorial problem in adolescent renal transplant recipients. Improving adherence in this patient demographic would benefit long-term patient and graft…2020 American Transplant Congress
Late Pneumocystis Jirovecii Pneumonia Often Misdiagnosed
*Purpose: Since 2/2018, we have identified 60 transplant recipients presenting with late PCR confirmed Pneumocystis jirovecii (PJP). Of this initial group, 17 kidney transplant recipients…2020 American Transplant Congress
Use of Tacrolimus Extended-Release in Elderly Kidney Transplant Recipients
1Barnes-Jewish Hospital, Saint Louis, MO, 2Washington University, Saint Louis, MO
*Purpose: Tacrolimus extended-release (LCPT) has been associated with efficacy and decreased rates of tremor when compared with tacrolimus immediate-release (Tac-IR) in kidney transplant recipients. Patients…2020 American Transplant Congress
Differences in Immunosuppressive Therapy among Liver Retransplantation Recipients in a National Cohort
Hospital of the University of Pennsylvania, Philadelphia, PA
*Purpose: There is no unified consensus as to the preferred immunosuppression (IS) strategy following liver retransplantation (reLT). This study explored: (i) factors associated with induction…2020 American Transplant Congress
Withaferin A Prolongs Islet Allograft Survival in a Mouse Transplant Model by Preventing T Lymphocyte Proliferation and Dendritic Cell Maturation
*Purpose: Chronic decline in islet graft function and toxicities imposed by immunosuppressant drugs remain as challenges to the widespread use of islet transplantation for type…2020 American Transplant Congress
Relationship between Tacrolimus Levels and Short-Term Outcome in Korean Pediatric Patients with Liver Transplantation
*Purpose: Liver transplantation (LT) is a life-saving procedure in patients with end stage liver disease. After LT, immunosuppresive regimens are needed in order to prevent…2020 American Transplant Congress
Long-Term Islet Allo- and Xenograft Survival is Promoted by Immunoglobulin M Immunotherapy
Department of Surgery, University of Virginia Health System, Charlottesville, VA
*Purpose: To investigate if islet allo- and xenotransplant rejection is mitigated by IgM immunotherapy.*Methods: a) New onset diabetic NOD mice (n=14) were treated with IgM…2020 American Transplant Congress
Polyoma Virus Infection in Renal Transplant Recipients Using Tacrolimo and Everolimo
*Purpose: Seropositivity for polyoma virus can reach 80% in kidney transplant recipients, with 1 to 10% polyoma associated nephropathy which negatively influences graft survival. Therefore,…2020 American Transplant Congress
PD-1 Signals Murine and Human Treg for Enhanced Migration
*Purpose: Programmed death-1 (PD-1) attenuates immune responses. Engagement of PD-1 by its ligands PD-L1 or PD-L2 regulates T cell development, proliferation, cytokine production, and apoptosis.…2020 American Transplant Congress
Challenging Dogma That Anti-Thymocyte Globulin Induction with Delayed Calcineurin Inhibitor Benefits Patients with Renal Insufficiency Undergoing Heart Transplant
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Anti-thymocyte globulin (ATG) induction is used in approximately 50% of heart transplant (HTx) patients in the United States to induce tolerance. Other programs only…
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