2020 American Transplant Congress
Simultaneous Pancreas-Kidney Transplant: – The Effects of Early Steroid Withdrawal, Donor and Recipient Variables on Patient Survival
*Purpose: Simultaneous pancreas-kidney transplantation (SPK) improves survival in type I diabetic patients with end stage renal disease (ESRD). Corticosteroids have traditionally been an integral component…2020 American Transplant Congress
Sparing the Nephron in Liver Transplant Recipients with Antithymocyte Bridging: A Four Year Experience
*Purpose: Renal function decline after liver transplant (LT) remains a significant issue. Using antithymocyte globulin (rATG) to delay tacrolimus (TAC) initiation may impact renal deterioration;…2020 American Transplant Congress
Depletional Profiles of Human and Rhesus Specific Anti-Thymocyte Globulins in Rhesus Macaques
*Purpose: Rabbit anti-human ATG (rATG; Thymoglobulin®) is the most commonly used formulation for depletional induction therapy in the United States. However, given that it is…2020 American Transplant Congress
Adenovirus Infection in Pediatric Liver Transplant Recipients: A Single Center Experience
*Purpose: Immunosuppression predisposes children to primary viral or latent infections after liver transplantation (LT). The impact of adenovirus infections on morbidity and mortality remains largely…2020 American Transplant Congress
Laminin Alpha5 Regulates T Cell Entry and Distribution in Lymph Nodes in Immunity
1UMB, Baltimore, MD, 2Harvard University, Boston, MA
*Purpose: Laminin α5 (Lama5) and α4 (Lama4) are lymph node (LN) stromal fibers whose expression ratio influences CD4+ T cell migration and stimulation. We hypothesized…2020 American Transplant Congress
Risk Factors for Antibody-Mediated Rejection after Adult Liver Transplantation with Preformed Donor-Specific Antibodies: A Single Center Experience
Div. of HBP Surgery and Transplantation, Dept. of Surgery, Kyoto University, Kyoto, Japan
*Purpose: In general, preformed donor-specific antibodies (pDSAs) can lead to an increased risk of antibody-mediated rejection (AMR); however, their prevalence, risk factors, and the efficacy…2020 American Transplant Congress
Donor-Derived DCREG Infusion Prolongs Kidney Allograft Survival in Rhesus Monkeys Treated with Co-Stimulation Blockade and Calcineurin Inhibition
Thomas E. Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: We have shown previously that pre-transplantation (Tx) infusion of donor-derived regulatory dendritic cells (DCreg) safely prolongs MHC-mismatched renal allograft survival and regulates donor-reactive T…2020 American Transplant Congress
Plasma Microbiome Profiles of Liver Transplant Patients with Operational Tolerance
*Purpose: Microbiome has emerged as a key modulator of organ homeostasis and immune system function with altered microbiota and microbiome - host interactions contributing to…2020 American Transplant Congress
The Use of Cell-Free MicroRNAs for the Diagnosis of Allograft Rejection in Liver Transplant Recipients Using Standard and Novel Direct Detection Platforms
*Purpose: Standard immunosuppression therapy (IST) in liver transplant (LTx) recipients requires a delicate balance to prevent side effects and allograft rejection (AR). There is no…2020 American Transplant Congress
Graft versus Host Disease in Liver Transplant Recipients: A Case Series
Cleveland Clinic Florida, Weston, FL
*Purpose: Graft Versus Host Disease (GvHD) is a serious and potentially fatal disease that is rarely observed in solid organ transplant recipients; however, we report…
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