2020 American Transplant Congress
Filgrastim Utilization Evaluation in Solid Organ Transplant Recipients
The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: Neutropenia occurs in up to 40% of kidney and liver transplant (txp) recipients and has been associated with higher mortality rates in liver txp.…2020 American Transplant Congress
Belatacept Monthly Therapy: Transplant Recipients’ Experience
*Purpose: While graft and patient outcomes with belatacept have been relatively well documented, the decision to use belatacept for kidney transplant recipients rests in part…2020 American Transplant Congress
Antibiotic Stewardship and Inpatient C. Difficile Testing in Solid Organ Transplant Recipients, the Value of Multi-Level Checks and Balances
University of Texas Medical Branch, Galveston, TX
*Purpose: Diarrhea in the solid organ transplant recipient is a commonly encountered problem and is often multifactorial in etiology. Due to the combination of peri-operative…2020 American Transplant Congress
Trough Level Compliance in Immunosuppression is Important to Protect Renal Function after Liver Transplantation – An Additional Analysis from the Hephaistos Study
1Hephaistos, Study Group, Germany, 2Novartis Pharma GmbH, Nürnberg, Germany
*Purpose: Most immunosuppressive drugs are dosed according to trough levels (C0-levels). To achieve the optimal balance between efficacy and safety, it is important to avoid…2020 American Transplant Congress
Effect of Maintaining Immunosuppression after Kidney Graft Failure on Mortality and Re-Transplantation
*Purpose: Patients with a failed renal allograft are at high risk for mortality. The potential benefit of maintaining immunosuppression with the intent to minimize sensitization…2020 American Transplant Congress
Unexpected Regulation of Foxp3+ Treg Production, Stability and Function by the Nuclear Co-Repressor, Sin3A
*Purpose: Foxp3+ T-regulatory (Treg) cells are crucial to immune homeostasis and self-tolerance, but the contributions to Tregs of the 4 large, multiprotein nuclear complexes (Sin3,…2020 American Transplant Congress
Adult Primary Liver Transplant Recipient Outcomes by Immunosuppression Induction Received
*Purpose: It has long been recognized that the highest risk of rejection of an organ is in the first few months post transplantation. To prevent…2020 American Transplant Congress
Transplant Relevant MDSC Genetics: Differential Gene Expression Profiles of Immunosuppressive Myeloid-Derived Suppressor Cells Induced by Granulocyte-Colony Stimulating Factor
Department of Surgery, University of Maryland, Baltimore, MD
*Purpose: Myeloid-derived suppressor cells (MDSC) are expanded in inflammation conditions and can control alloreactive T cell responses. Granulocyte-colony stimulating factor (GCSF) is known to induce…2020 American Transplant Congress
Impact of Donor Race on Tacrolimus Dose Requirement for Liver Transplant Recipients
*Purpose: It is well described that there is interpatient variability in tacrolimus dose requirements among transplant recipients. CYP3A5 plays a role in this variability. Black…2020 American Transplant Congress
Impact of Immunosuppression on Quality of Life among HLA-Identical Living Kidney Recipients at UCLA – A Qualitative Study
*Purpose: Tolerant kidney transplant recipients (off immunosuppression) report higher self-rated quality of life and a lower symptom burden compared to standard living recipients when using…
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