2020 American Transplant Congress
Antibiotic Stewardship and Inpatient C. Difficile Testing in Solid Organ Transplant Recipients, the Value of Multi-Level Checks and Balances
University of Texas Medical Branch, Galveston, TX
*Purpose: Diarrhea in the solid organ transplant recipient is a commonly encountered problem and is often multifactorial in etiology. Due to the combination of peri-operative…2020 American Transplant Congress
Trough Level Compliance in Immunosuppression is Important to Protect Renal Function after Liver Transplantation – An Additional Analysis from the Hephaistos Study
1Hephaistos, Study Group, Germany, 2Novartis Pharma GmbH, Nürnberg, Germany
*Purpose: Most immunosuppressive drugs are dosed according to trough levels (C0-levels). To achieve the optimal balance between efficacy and safety, it is important to avoid…2020 American Transplant Congress
Effect of Maintaining Immunosuppression after Kidney Graft Failure on Mortality and Re-Transplantation
*Purpose: Patients with a failed renal allograft are at high risk for mortality. The potential benefit of maintaining immunosuppression with the intent to minimize sensitization…2020 American Transplant Congress
Unexpected Regulation of Foxp3+ Treg Production, Stability and Function by the Nuclear Co-Repressor, Sin3A
*Purpose: Foxp3+ T-regulatory (Treg) cells are crucial to immune homeostasis and self-tolerance, but the contributions to Tregs of the 4 large, multiprotein nuclear complexes (Sin3,…2020 American Transplant Congress
Evaluation of Rejection, Infection, and Malignancy Outcomes in Elderly Liver Transplant Recipients Compared to a Younger Cohort
*Purpose: Previous data has shown elderly liver transplant recipients (LTx) to be at a lower risk of acute rejection than younger recipients. As such, elderly…2020 American Transplant Congress
Establishing an Induction Protocol for Long-Term Multilineage Mixed Chimerism in Rhesus Macaques
*Purpose: Mixed chimerism (MC) induction via non-myeloablative conditioning and bone marrow transplantation (BMT) induces tolerance to solid organs. Our standard MC induction protocol in cynomologous…2020 American Transplant Congress
Stanford Integrated Psychosocial Assessment for Transplant Predicts Immunosuppression Non-Adherence after Liver Transplantation
*Purpose: Patients with end-stage liver disease presenting for liver transplant (LT) evaluation have a high burden of psychosocial comorbidities. The Stanford Integrated Psychosocial Assessment for…2020 American Transplant Congress
Remote Steroid Wean is Safe When Compared to Early Wean in Heart Transplant Recipients
Cardiovascular Disease, Heart Failure and Transplant, Houston Methodist Hospital, Houston, TX
*Purpose: The risks and benefits of remote steroid wean in heart transplant recipients is unknown. We compared outcomes in patients undergoing early and remote steroid…2020 American Transplant Congress
Sirolimus Combined with Low-Dose Calcineurin Inhibitor in Kidney Transplant Recipients from Expanded Criteria Donors
Beijing Friendship Hospital, Capital Medical University, Beijing, China
*Purpose: To evaluate the efficacy and safety of conversion from calcineurin inhibitor-based immunosuppressive regimen to sirolimus combined with low-dose calcineurin inhibitor in recipients with abnormal…2020 American Transplant Congress
T Cell Hyporesponsiveness in Kidney Transplant Recipients is Associated with Urinary Tract Infections and Age of Kidney Transplant: Implications for Allograft Nephropathy
Dept of Nephrology, University of KwaZulu-Natal, Durban, South Africa
*Purpose: Chronic allograft nephropathy is the main cause of kidney graft loss. With the use of potent immunosuppressive treatments, acute rejections are less and less…
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