2016 American Transplant Congress
The Impact of Ritonavir-Boosted Protease Inhibitors and Non-Depleting Antibody Induction on Outcomes in HIV-Infected Kidney Transplant Recipients.
Mount Sinai Hospital, New York.
Background: One-year rejection rates in HIV-infected kidney transplant recipients range from 15-40%, compared to overall rejection rates of 10% in HIV-negative patients. Protocols for immunosuppression…2016 American Transplant Congress
Early Steroid Withdrawal in African American Kidney Transplant Recipients: A Propensity Score Matching Analysis.
Objective: The aim of this study was to assess the safety of steroid withdrawal in African American (AA) kidney transplant (KTX) recipients.Methods: Longitudinal cohort study…2016 American Transplant Congress
ABO-Incompatible Living Kidney Transplantation at Multicenter Japanese Case Series: Evolution of Outcomes and Immunosuppressive Management.
[lsaquo]Background[rsaquo]ABO-incompatible living kidney transplantation (ABO-ILKT) has been performed to broaden the range of donor types used for living related kidney transplantation (LKT). Recently, ABO-ILKT has…2016 American Transplant Congress
Aging Is Critically Impacting the Efficacy of Immunosuppressants.
Immunosenescence is broadly affecting alloimmunity with major implications on immunosuppression. Older recipients have thus far been mostly excluded from clinical trials. Here, we dissected the…2016 American Transplant Congress
Clinical Outcomes of Simplified Once-Daily Immunosuppressive Regimen for Kidney Recipients.
Background. Many of immunosuppressive drugs have been prescribed as twice-daily dosing. Simplified once-daily dosing of the entire drug regimen can enable patients to improve treatment…2016 American Transplant Congress
Achieving Timely Therapeutic Mycophenolic Acid Levels in Pediatric Lung Transplant Patients.
Texas Children's Hospital, Houston, TX.
The purpose of this study was to determine the appropriate initial dose of mycophenolate mofetil (MMF) in pediatric cystic fibrosis (CF) and non-CF lung transplant…2016 American Transplant Congress
The Effect of Immunosuppression Regimen on Iga Nephropathy Recurrence Post Kidney Transplantation.
Background: Steroid sparing immunosuppression is increasingly used in order to avoid the many well-known side effects of steroids. It has been argued that steroid use…2016 American Transplant Congress
Conversion to Belatacept as Rescue Therapy in Kidney Transplant Recipients with Severe Graft Dysfunction.
Belatacept is a fusion protein that prevents T cell co-stimulation via the CD28 receptor. If used as first-line therapy, immunosuppression with Belatacept is associated with…2016 American Transplant Congress
Marked Alterations in Gene Expression in Peripheral Blood Leukocytes of Kidney Transplant (tx) Recipients Following Mycophenolic Acid (MPA) Treatment.
1University of Minnestoa, Minneapolis; 2MMRC, Hennepin County Medical Center, Minneapolis; 3Rho.
MPA exerts its immunosuppressive activity by inhibiting IMPDH2 enzyme, halting DNA synthesis in T and B lymphocytes. Cell culture models have shown MPA effects on…2016 American Transplant Congress
Influence of the Tacrolimus Metabolism Rate on BKV Infection After Kidney Transplantation.
Introduction: BK virus (BKV) infection is a serious complication following renal transplantation (RTx). The minimization of risk factors that predict BKV infection might help to…
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