ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2016 American Transplant Congress

    A Change in Insulin Sensitivity and Lipid Profile in Renal Transplant Recipients Converted from Cyclosporine or Standard Release Tacrolimus to Once-Daily Prolonged Release Tacrolimus.

    Y. Jung,1 Y. Kim,1 S. Kim,1 H. Shin,1 H. Rim,1 H. Rhew.2

    1Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea; 2Urology, Kosin University College of Medicine, Busan, Republic of Korea.

    Background : New-onset diabetes after transplantation may be associated with the use of tacrolimus (Tac) causing impaired insulin release or reduced insulin sensitivity. And, dyslipidemia…
  • 2016 American Transplant Congress

    Conversion from Tacrolimus (TAC) to Sirolimus (SLR)-Based Immunosuppression in Pediatric Patients Who Underwent Liver Transplantation for Unresectable Hepatoblastoma – 2 Year Follow-Up.

    R. Hendrickson,1 W. Andrews,1 M. Davis,1 R. Cisneros,1 R. Fischer,2 J. Daniel.2

    1Pediatric/Transplant Surgery, Children's Mercy Hospitals and Clinics, Kansas City, MO; 2Hepatology, Children's Mercy Hospitals and Clinics, Kansas City, MO.

    Introduction: The appropriate use of Sirolimus (SRL) immunosuppression in pediatric liver transplantation has yet to be clearly defined. Even though Tacrolimus (TAC) is commonly used…
  • 2016 American Transplant Congress

    Prospective Randomized Controlled Study Evaluating the Impact of an Electronic Feedback System on Medication Adherence in Solid Organ Transplantation.

    M. Lockwood, L. Potter, B. Kane, L. Lourenco, A. Bozdin, J. Millis.

    University of Chicago Transplant Center, University of Chicago, Chicago.

    Purpose: To evaluate the impact of and electronic feedback system (EFS), SIMpill Medication Adherence System®, on medication adherence in patients who have received a solid…
  • 2016 American Transplant Congress

    Belatacept Does Not Inhibit Plasmablast Formation Supported by Follicular T Helper Cells, but Favors the Development of Transitional Regulatory B Cells in Kidney Transplant Patients.

    G. de Graav, D. Hesselink, M. Dieterich, R. Kraaijeveld, W. Weimar, C. Baan.

    Internal Medicine, Section Transplantation and Nephrology, Erasmus University Medical Center, Rotterdam, South Holland, Netherlands.

    Since the costimulatory inhibitor belatacept effectively blocks T-B cell interaction in animal transplant models, we studied the functional follicular T helper cells (TFH)-B cell interaction…
  • 2016 American Transplant Congress

    The Impact of Ritonavir-Boosted Protease Inhibitors and Non-Depleting Antibody Induction on Outcomes in HIV-Infected Kidney Transplant Recipients.

    B. Rollins, S. Lerner, M. Rana, S. Huprikar, L. Miko, V. Nair, S. Florman, R. Shapiro.

    Mount Sinai Hospital, New York.

    Background: One-year rejection rates in HIV-infected kidney transplant recipients range from 15-40%, compared to overall rejection rates of 10% in HIV-negative patients. Protocols for immunosuppression…
  • 2016 American Transplant Congress

    Early Steroid Withdrawal in African American Kidney Transplant Recipients: A Propensity Score Matching Analysis.

    D. Taber, M. Gebregziabher, T. Srinivas, K. Chavin, P. Baliga, L. Egede.

    MUSC, Charleston, SC.

    Objective: The aim of this study was to assess the safety of steroid withdrawal in African American (AA) kidney transplant (KTX) recipients.Methods: Longitudinal cohort study…
  • 2016 American Transplant Congress

    ABO-Incompatible Living Kidney Transplantation at Multicenter Japanese Case Series: Evolution of Outcomes and Immunosuppressive Management.

    K. Tanabe,1 M. Okumi,1 M. Furusawa,1 K. Unagami,1 T. Hirai,1 H. Shirakawa,2 T. Shimizu,1 K. Omoto,3 M. Inui,1 H. Ishida.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Urology, Ohkubo Hospital, Tokyo, Japan; 3Urology, Todachuo General Hospital, Saitama, Japan.

    [lsaquo]Background[rsaquo]ABO-incompatible living kidney transplantation (ABO-ILKT) has been performed to broaden the range of donor types used for living related kidney transplantation (LKT). Recently, ABO-ILKT has…
  • 2016 American Transplant Congress

    Aging Is Critically Impacting the Efficacy of Immunosuppressants.

    J. Schuitenmaker, K. Edtinger, M. Seyda, H. Uehara, M. Quante, A. ElKhal, S. Tullius.

    Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

    Immunosenescence is broadly affecting alloimmunity with major implications on immunosuppression. Older recipients have thus far been mostly excluded from clinical trials. Here, we dissected the…
  • 2016 American Transplant Congress

    Clinical Outcomes of Simplified Once-Daily Immunosuppressive Regimen for Kidney Recipients.

    C.-K. Oh,1 S.-J. Kim,2 K. Huh,3 S. Kim,4 H. Cho,5 S. Lee.6

    1Surgery, Ajou University School of Medicine, Suwon, Republic of Korea; 2Surgery, Samsung Medical Center, Seoul, Republic of Korea; 3Surgery, Yonsei University Health System, Seoul, Republic of Korea; 4Surgery, CHA University School of Medicine, Pocheon, Republic of Korea; 5Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 6Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.

    Background. Many of immunosuppressive drugs have been prescribed as twice-daily dosing. Simplified once-daily dosing of the entire drug regimen can enable patients to improve treatment…
  • 2016 American Transplant Congress

    Achieving Timely Therapeutic Mycophenolic Acid Levels in Pediatric Lung Transplant Patients.

    C. Kam, S. Kim, E. Melicoff.

    Texas Children's Hospital, Houston, TX.

    The purpose of this study was to determine the appropriate initial dose of mycophenolate mofetil (MMF) in pediatric cystic fibrosis (CF) and non-CF lung transplant…
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