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American Transplant Congress abstracts

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Articles tagged "Image analysis"

  • 2021 American Transplant Congress

    Novel Morphologic Biomarkers of Cardiac Allograft Remodeling are Associated with Multiple Peri- and Post-transplant Inflammatory Processes

    C. Yuan1, S. Arabyarmohammadi1, H. Li1, E. Peyster2, P. Lal3, M. Feldman3, K. Margulies2, A. Madabhushi1

    1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 2Cardiovascular Research Institute, University of Pennsylvania, Philadelphia, PA, 3University of Pennsylvania, Philadelphia, PA

    *Purpose: It has long been recognized that transplanted hearts develop a stiffened, restrictive physiology at an accelerated rate compared to native hearts. While this is…
  • 2021 American Transplant Congress

    Indocyanine Green Fluorescence Imaging Allows Quantification of Ischemic Injury During Porcine Normothermic Ex Situ Perfusion

    T. Goto, Y. Noguchi, S. Ganesh, L. Mazilescu, T. Reichman, N. Selzner, M. Selzner

    Ajmera Transplant Program, Department of Surgery, Toronto General Hospital, Toronto, ON, Canada

    *Purpose: Normothermic Ex Situ Liver Perfusion (NEsLP) is a novel preservation technique for the storage and assessment of grafts retrieved after Donation after Cardio-circulatory Death…
  • 2021 American Transplant Congress

    Dissecting the Intrarenal Immune Response to Viral Infected Cells in Pediatric BK Virus-associated Nephropathy (BKVAN)

    D. M. Okamura1, S. W. Jackson1, V. R. Dharnidharka2, J. M. Smith1

    1Pediatric Nephrology, Seattle Children's Hospital & Research Institute, Seattle, WA, 2Pediatric Nephrology, 2St. Louis Children’s Hospital, Washington University School of Medicine, St. Louis, MO

    *Purpose: BKVAN is not only a cause of acute renal allograft injury but is a recognized cause of chronic allograft disease and in some patients,…
  • 2020 American Transplant Congress

    Neonatal Tolerance Induction: Behaviours of Allogeneic Spleen and Bone Marrow Inocula in Neonatal Mice are Largely Determined by the Nature of Their CD8 T Cells

    R. A. Bascom, K. Tao, L. J. West

    University of Alberta, Edmonton, AB, Canada

    *Purpose: Injected adult allo-spleen (SC) and bone marrow cells (BMC) traffic to secondary lymphoid organs, proliferate and spread throughout neonatal mice; allo-SC consistently cause acute…
  • 2020 American Transplant Congress

    Steatosis by PDFF Affects Percent Remnant Liver Regeneration in Living Donors without Impacting on Clinical Outcomes

    A. Duarte-Rojo, Q. Qi, K. Chupetlovska, D. R. Jorgensen, A. A. Borhani, A. Furlan, S. Ganesh, A. Humar

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Mild steatosis (5-33% of fat) is not expected to affect liver regeneration following partial hepatectomy. Novel methods to assess steatosis, such as proton density…
  • 2020 American Transplant Congress

    Impact of Kidney Transplant Type and Previous Transplant on Baseline Donor-Derived Cell Free DNA

    K. K. Sureshkumar, B. Chopra

    Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA

    *Purpose: Donor derived-cell free DNA (dd-cfDNA) is a biomarker useful in predicting acute rejection in renal allografts. The technology uses next generation sequencing and does…
  • 2020 American Transplant Congress

    Photo Elicitation Interviewing Exposes Educational Discordance Amidst a Web of Resources among Kidney Transplant Recipients

    J. R. Montgomery, M. J. Kirsch, A. Rau, M. E. Byrnes, S. A. Waits

    General Surgery, University of Michigan, Ann Arbor, MI

    *Purpose: Comprehensive patient education is the bedrock of success for kidney transplant (KT) recipients. Despite the importance, we have a poor understanding of how patients…
  • 2020 American Transplant Congress

    Hyperspectral Imaging of Human Kidney Allografts

    R. Sucher1, H. Köhler2, A. Lederer1, H. M. Hau1, I. Gockel1, D. Seehofer1

    1Department of Visceral, Transplant-, Thoracic and Vascular Surgery, University Clinic Leipzig, Leipzig, Germany, 2Innovation Center for Computer Assisted Surgery, University Clinic Leipzig, Leipzig, Germany

    *Purpose: Hyperspectral imaging (HSI) is capable to deliver non-contact, non-ionizing and non-invasive quantitative diagnostic information about tissue pathology, morphology and composition, based on the spectral…
  • 2020 American Transplant Congress

    Accelerated Decline in Glomerular Density: An Unrecognized Pathologic Process after Kidney Transplantation

    A. Denic, B. H. Smith, W. D. Park, M. V. Luhman, M. P. Alexander, A. D. Rule, M. D. Stegall

    Mayo Clinic, Rochester, Rochester, MN

    *Purpose: Studies in healthy adults have shown that glomerular density slowly declines with older age (-0.5% per decade), and globally sclerotic glomeruli (GSG) slowly increase…
  • 2020 American Transplant Congress

    Kidney Cortical Wedge Biopsies for Human Organ Research: Does Anatomic Variability Impact Their Utility?

    C. M. Edwards1, J. T. Langford1, M. Reschke2, J. R. DiRito1, D. Mulligan1, D. Haakinson1, G. T. Tietjen1

    1Surgery, Yale School of Medicine, New Haven, CT, 2Biomedical Engineering, Yale University, New Haven, CT

    *Purpose: The purpose of this study is to characterize human kidney anatomic variability both within singular biopsies and between biopsy sites in order to investigate…
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