2019 American Transplant Congress
Individualized Preconditioning for ABO-Incompatible Living Donor Kidney Transplantation: An Initial Report of 48 Cases from China
*Purpose: Typically, the majority of centres that perform ABO incompatible (ABOi) kidney transplantation use fixed preconditioning protocols regardless of the initial titer. As experience in…2019 American Transplant Congress
Liver Transplantation in Children with Type 1 and Type 2 Autoimmune Hepatitis
Department of Student Affairs, Baylor College of Medicine, Houston, TX
*Purpose: Autoimmune Hepatitis (AIH) can be defined as type 1 and type 2 based on autoantibodies. Liver transplant (LT) may be indicated for chronic liver…2019 American Transplant Congress
QA of MMR/VZV Protocol-Driven Serologic Screening and Infectious Disease Consultation (IDC) Are Strongly Recommended in Heart, Lung, Liver (HLL) SOTs
*Purpose: SOT recipients are at risk of acquiring life-threatening infections putting their graft and life at risk. Prevention, including immunization with live virus vaccines pre-transplantation…2019 American Transplant Congress
Variable Glycosylations of Anti-HLA Antibodies Detected with Single Antigen Beads in Kidney Transplant Recipients
*Purpose: Differential glycosylation of Immunoglobulin G (IgG) is known to affect its effector functions by modulating interactions with its binding partners, such as C1q or…2018 American Transplant Congress
Follow Up of Patients Treated with the IgG Endopeptidase (IdeS) for Desensitization and HLA Incompatible (HLAi) Kidney Transplantation
Introduction:Donor-specific antibodies (DSAs) create an immunologic barrier to transplantation. This prevents transplantation for a significant percentage of highly-HLA sensitized patients (HS). Current desensitization therapies are…2018 American Transplant Congress
Role of Calcium/Calmodulin Kinase IV on Podocyte Function in Transplant Glomerulopathy
Beth Israel Deaconess Medical Center, Boston.
Background : Transplant glomerulopathy(TG) a histological manifestation of chronic antibody mediated rejection and a major cause of late allograft loss. It is well accepted that…2018 American Transplant Congress
IgG De Novo HLA Antibody Subclass Analysis in Patients Undergoing Allograft Nephrectomy after Transplant Failure
Introduction: different immunising events can stimulate the production of disparate antibody subclass profiles, reflecting a diverse extent of T-cell activation. Transplant nephrectomy (NX) is a…2018 American Transplant Congress
Multi-Targeting Desensitization Therapy Alters Peripheral B-Cell Homeostasis and Suppresses Recall Alloantibody Responses
CTC/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Purpose: Occurring of donor specific antibodies (DSA) is injurious to organ transplant. Development of immunotherapies to suppress DSA, therefore, has been one of the strategic…2018 American Transplant Congress
Long Term Culture of Functional Bone Marrow-Derived Human Plasma Cells
Introduction Antibody-secreting plasma cells (PCs) are critically important for host defense, but also can cause antibody-mediated allograft rejection. The ability to study these cells is…2018 American Transplant Congress
Class II Anti-HLA IgG2 and IgG3 DSAs Predict Poorer Outcomes in Chronic Antibody Mediated Rejection of Renal Allografts
Introduction: whilst the development of IgG3 and C1q binding de novo [dn] HLA DSAs are associated with a poor outcome in acute antibody mediated rejection,…
American Transplant Congress abstracts