2018 American Transplant Congress
Antihypertensive Medication Use after Kidney Transplant: Practice Variation and Clinical Outcomes
Hypertension is common among kidney transplant (KTx) recipients, but the impact of antihypertensive medication (AHM) choice on patient and graft outcomes is not well defined.We…2018 American Transplant Congress
CD40 Signaling in Proximal Tubules Regulates Fibrosis in Both Hypertension and Chronic Allograft Rejection
University of Toledo College of Medicine and Life Sciences, Toledo, OH.
Background: We explored the role of CD40 signaling in kidney proximal tubule epithelial cells on renal interstitial fibrosis (IF) in two models: hypertension; and chronic…2018 American Transplant Congress
Evaluation of Salt Intake by 24-h Urinary Sodium Excretion in Kidney Transplant Patients
Background: Dietary recommendations for chronic kidney disease advise 3 to 6 g/day of dietary salt intake. We evaluated current adherence to dietary recommendations for CKD…2018 American Transplant Congress
Race/Ethnicity and Hypertension Self-Care Behaviors among US Living Kidney Donors
Purpose: Despite the success of live donor kidney transplantation as an optimal treatment for ESRD, some living kidney donors may be at increased risk of…2018 American Transplant Congress
Krüppel-Like Factor 15 is a Key Suppressor of the Glomerular Epithelial Cell Fibrosis under Centrifugal Force Driven Pressure
Hypertension is known to be responsible for a reduction in the number of functional nephrons of glomeruli due to fibrosis, which develops into a chronic…2018 American Transplant Congress
Single versus Bilateral Simultaneous Nephrectomy during Kidney Transplantation in Autosomal Dominant Polycystic Kidney Disease
PurposeAlthough there are some controversies about nephrectomy in patient with autosomal dominant polycystic kidney disease (ADPKD), simultaneous nephrectomy has done selectively. There are few report…2018 American Transplant Congress
Diagnostic Performance of Blood Pressure Measurement Modality in Prospective Living Kidney Donors
Nephrology, Cleveland Clinic, Cleveland, OH.
Background: Precise blood pressure (BP) measurement to exclude hypertension (HTN) is critical in evaluating living kidney donors (LKDs). 24-hour ambulatory blood pressure monitoring (ABPM) is…2018 American Transplant Congress
Renal Function, Blood Pressure, and Histologic Changes in Living Kidney Transplant Recipients from Hypertensive Donors
Little is known if a kidney from a hypertensive donor performs equally compared to a kidney from a non-hypertensive donor. The present study examines the…2018 American Transplant Congress
Nephrosclerosis beyond That Expected for Age is Predictive of Early New-Onset Hypertension (HTN) in Living Kidney Donors (LKD)
1Mayo Clinic, Rochester, MN; 2Mayo Clinic, Scottsdale, AZ; 3Cleveland Clinic, Cleveland, OH.
Background: Nephrosclerosis on biopsy (bx) of LKD is associated with older age & HTN. We studied whether nephrosclerosis is predictive of adverse changes early after…2017 American Transplant Congress
Impact of Antihypertensive (AHT) Choice and Advagraf® Dose on Interstitial Fibrosis/Tubular Atrophy (IF/TA) and IF/TA Progression in Renal Allografts 24 Months Post-Transplantation (Tx).
IF/TA may be delayed using ACEi- or ARB-type AHTs, which target the renin-angiotensin system (RAS), as well as by optimizing tacrolimus (TAC) exposure. The effect…
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