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Articles tagged "Hyperglycemia"

  • 2020 American Transplant Congress

    Sequential Protocol Biopsies Post-Liver Transplant from Donors with Moderate Macrosteatosis: What Happens to the Fat?

    K. Croome, D. Livingston, C. Taner, R. Nakhleh

    Mayo Clinic Jacksonville, Jacksonville, FL

    *Purpose: The number of steatotic deceased donor livers encountered has continued to rise as a result of the obesity epidemic. Little is known about the…
  • 2020 American Transplant Congress

    Characterization of Use and Safety of Non-Insulin Agents for Management of Post-Transplant Diabetes Mellitus in the Kidney Transplant Population

    M. Norris1, J. Trofe-Clark1, C. Sammons1, N. Casciello1, S. Cardillo2, D. Sawinski3, R. D. Bloom3, G. Malat1

    1Pharmacy, Hosp of Univ of Pennsylvania, Philadelphia, PA, 2Endocrine Div, Univ of Pennsylvania, Philadelphia, PA, 3Renal Div, Univ of Pennsylvania, Philadelphia, PA

    *Purpose: Newer, non-insulin agents appear to have significant cardiovascular benefits. However, use of these agents for diabetes (DM) management in kidney transplant recipients (KTR) has…
  • 2020 American Transplant Congress

    GLP1-RAs, SGLT2i Are Underutilized in Kidney Transplant Recipients with Diabetes Mellitus and Obesity

    M. Stumpf, S. A. Dar, S. Rao, A. Doyle

    University of Virginia, Charlottesville, VA

    *Purpose: There is little research describing differences in use of antidiabetic medications amongst obese, diabetic patients with or without a history of kidney transplant. More…
  • 2020 American Transplant Congress

    Diabetes Burnout: An Under-Recognized Risk-Factor in Post-Transplant Care Management

    N. Pilch, P. Baliga, V. Rao, V. Rohan, K. Foster, H. Perkins, N. Patel, D. Dubay, D. Taber

    Medical University of South Carolina, Charleston, SC

    *Purpose: One-third of dialysis patients will have spontaneous glycemic control improvement, necessitating discontinuation of antihyperglycemic therapy, termed diabetes burnout. The aim of this study was…
  • 2019 American Transplant Congress

    HbA1c as a Noninvasive Predictor of Chronic Histopathologic Changes in Living Donors for Kidney Transplantation

    K. Tanaka1, S. Nishida1, K. Kinoshita1, Y. Hidaka1, M. Toyoda2, A. Inadome3, A. Takeda4, H. Yokomizo5, S. Uekihara6, J. Shoji7, S. Yamanaga1

    1Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, 2general medicine, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, 3Urology, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, 4Nephrology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Japan, 5Surgery, Japanese Red Cross Kumamoto Hospital, kumamoto, Japan, 6general medicine, Japanese Red Cross Kumamoto Hospital, kumamoto, Japan, 7Nephrology, UCSF Connie Frank Transplant Center, San francisco, CA

    *Purpose: The degree of chronic histopathologic changes in renal allografts, including interstitial fibrosis, tubular atrophy, and arteriolar hyalinosis, can have clinical implications in long-term allograft…
  • 2019 American Transplant Congress

    Impact of Hepatitis C Viremia on Post-Transplant Diabetes Mellitus Development in Liver Transplant Recipients

    K. Klein1, J. Nelson2, B. Crowther1, C. Guerra3, E. Kincaide1, K. V. Speeg4, N. Alkhouri5, R. Hall1

    1University Health System, The University of Texas at Austin, College of Pharmacy, Pharmacotherapy Division, Austin, TX, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 2University Health System, San Antonio, TX, 3The University of Texas Health Science Center at San Antonio, University of the Incarnate Word Feik School of Pharmacy, San Antonio, TX, 4University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 5University Health System, The University of Texas Health Science Center at San Antonio, Texas Liver Institute, San Antonio, TX

    *Purpose: Compare incidence of post-transplant diabetes mellitus (PTDM) in hepatitis C virus (HCV) patients with and without viremia at the time of orthotopic liver transplantation…
  • 2019 American Transplant Congress

    Hyperglycemia Aggravates Acute Liver Injury by Promoting Macrophage NLRP3 Activation via AMPK/mTOR-Dependent Autophagy Inhibition

    H. ZHOU, Q. Wang, R. Liu, S. Zhou, F. Cheng, X. Wang, L. Lu

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: The detrimental effects of diabetes mellitus/hyperglycemia include an increase in the oxidative stress response and an enhanced inflammatory response. Despite an increased understanding of…
  • 2019 American Transplant Congress

    Inpatient versus Outpatient Management of Hyperglycemia in Post-Transplant Patients Following High Dose Steroid Pulses for Acute Rejection

    J. L. Wisniewski1, W. Bruneau2, E. A. Cohen2

    1University of Connecticut, School of Pharmacy, Storrs, CT, 2Yale New Haven Hospital, New Haven, CT

    *Purpose: Acute cellular rejection (ACR) occurs in approximately ten percent of all transplant patients and is typically treated with multiple infusions of high-dose steroids (HDS).…
  • 2019 American Transplant Congress

    Use of GLP-1 Receptor Agonists in Kidney Transplant Recipients with Type 2 Diabetes

    A. Kukla, J. Hill, M. Merzkani, A. Bentall, E. Lorenz, W. Park, P. Shah, N. Issa, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: GLP-1 receptor agonists have been shown to improve glucose control and diabetes-related comorbidities, including obesity, cardiovascular disease and chronic kidney disease, in non-transplant patients.…
  • 2019 American Transplant Congress

    Pharmacist-Led Management of Post-Transplant Hyperglycemia Reduces Hospitalizations

    V. H. Do1, I. Figueroa2, A. Elshafie3, R. Belfort De Aguiar3, D. Haakinson3, E. Cohen1

    1Yale New Haven Hospital, New Haven, CT, 2Western New England School of Pharmacy, Springfield, MA, 3Yale School of Medicine, New Haven, CT

    *Purpose: Renal transplant recipients (RTRs) are at risk of developing post-transplant hyperglycemia (PTHG), defined as blood glucose > 180 mg/dL within the first 45 days…
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