Articles tagged "Hyperglycemia"

2020 American Transplant Congress
Progression of Insulin Resistance after Liver Transplantation – Prospective Study
I. Mikova¹, D. Erhartova¹, K. Dvorakova¹, P. Sedivy², M. Drobny², M. Dezortova², M. Hajek², M. Cahová³, H. Dankova³, E. Sticova⁴, V. Lanska⁵, P. Trunecka¹
¹Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²Radiodiagnostic and Interventional Radiology Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ³Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁴Department of Clinical and Transplant Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁵Medical Statistics Unit, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Insulin resistance (IR) plays an important role in pathogenesis of nonalcoholic fatty liver disease (NAFLD) and other diseases. The data about prevalence and evolution…
2020 American Transplant Congress
New-Onset Diabetes after Adult Liver Transplantation in the Korean Organ Transplantation Registry Study
J. Kim¹, S. Hwang², K. Lee³, J. Lee⁴, J. Ryu⁵, B. Kim⁶, D. Choi⁷, Y. You⁸, D. Kim⁹, Y. Nah¹⁰, K. Kang¹¹, M. Kim⁴
¹Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, ²Department of Surgery, Asan Medical Center, College of Medicine University of Ulsan, Seoul, Korea, Republic of, ³Department of Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, ⁴Department of Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of, ⁵Department of Surgery, Pusan National University College of Medicine, Busan, Korea, Republic of, ⁶Department of Liver Transplantation and Hepatobiliary Surgery, Ajou University School of Medicine, Suwon, Korea, Republic of, ⁷Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of, ⁸Department of Surgery, College of Medicine, Catholic University of Korea, Seoul, Korea, Republic of, ⁹Division of HBP Surgery and Liver Transplantation, Department of Surgery, Korea University College of Medicine, Seoul, Korea, Republic of, ¹⁰Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea, Republic of, ¹¹Department of Surgery, Keimyung University School of Medicine, Daegu, Korea, Republic of
*Purpose: New-onset diabetes after transplantation (NODAT) is a serious complication following liver transplantation (LT). The present study aimed to investigate the incidence of and risk…
2020 American Transplant Congress
Significant Costs Associated with Poorly Controlled Post-Transplant Blood Glucose
H. Yerneni¹, K. Chavin², T. Srinivas¹, A. Padiyar¹
¹Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, ²Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH
*Purpose: Dysglycemia is highly prevalent post-transplant. Poor glycemic control is associated with infectious and cardiovascular complications, as well as decreased patient and allograft survival. We…
2020 American Transplant Congress
Early Worsening of Diabetic Retinopathy after Pancreas and Kidney Transplantation: Myth or Reality?
F. Saudek¹, B. Voglová¹, K. Kesslerová², T. Sosna², K. Lipár³
¹Diabetes Center, Institute for Clinical and Experimental Medicine, Praha 4, Czech Republic, ²Ophthalmology, Thomayer Hospital, Praha 4, Czech Republic, ³Transplant Center, Institute for Clinical and Experimental Medicine, Praha 4, Czech Republic
*Purpose: Type-1 diabetic pancreas and kidney transplant candidates frequently suffer from advanced diabetic retinopathy. Early worsening of diabetic retinopathy (EWDR) attributed to sudden glucose normalization…
2019 American Transplant Congress
Prevention of Diabetes in the NOD Mice Reconstituted with Bone Marrow Cells from Allogeneic CD4 Knockout, CD8 Knockout or B-Cell Knockout B6 Mice
Y. Huang, H. Xu, Y. Wen, S. Ildstad
University of Louisville, Louisville, KY
*Purpose: Type 1 diabetes (T1D) is an autoimmune disorder characterized by destruction of the pancreatic beta cells by both humoral- and cell-mediated immune mechanisms. Transplantation…
2019 American Transplant Congress
Prevention of Islet Allo- and Xenograft Rejection with Immunoglobulin M Immunotherapy
M. Ma, P. Chhabra, K. Brayman
Surgery, University of Virginia, Charlottesville, VA
*Purpose: To investigate if IgM therapy mitigates islet allo- and xenotransplant rejection and promotes permanent islet survival.*Methods: 1) New onset diabetic NOD mice (n=14) were…
2019 American Transplant Congress
FK506 Influence Glucose Metabolism by Short Chain Fatty Acid
W. Jiao¹, Z. Zhang¹, L. Liu², X. Hu¹
¹Urology, Capital Medical University Beijing Chaoyang Hospital, Beijing, China, ²GI Divison, West China Hospital, Beijing, China
*Purpose: FK506 is one of the most common immunosuppressant drugs in organ transplantation, which have been demonstrated to cause glucose metabolism disorder and alterd the…
2019 American Transplant Congress
Belatacept Based Simultaneous Calcineurin Inhibitor Avoidance/Early Corticosteroid Withdrawal is Associated with Low New Onset Diabetes Risk
A. R. Shields¹, P. West-Thielke², E. S. Woodle¹, D. B. Kaufman³, J. Lipscomb⁴, J. P. Leone⁵, A. Wiseman⁶, E. King⁴, A. J. Matas⁷, R. R. Alloway for the BEST Study Group⁴
¹Transplant Surgery, U of Cincinnati, Cincinnati, OH, ²UIC, Chicago, IL, ³Transplant Surgery, U of Wisconsin, Madison, WI, ⁴U of Cincinnati, Cincinnati, OH, ⁵Tampa General, Tampa, FL, ⁶U of Colorado, Denver, CO, ⁷U Minnesota, Minneapolis, MN
*Purpose: Calcineurin inhibitor (CNI) and/or corticosteroid (CCS) therapy are associated with significant risk of new onset diabetes after transplantation (NODAT). An important consideration for simultaneous…
2019 American Transplant Congress
The Impact of Sleeve Gastrectomy Following Liver Transplant in Patients with Non-Alcoholic Steatosis: A Five-Year Experience
M. C. Morris¹, A. D. Jung¹, Y. Kim¹, V. K. Dhar¹, S. Shah¹, D. Schauer², E. Smith², T. Diwan¹
¹Surgery, University of Cincinnati, Cincinnati, OH, ²Medicine, University of Cincinnati, Cincinnati, OH
*Purpose: Non-alcoholic steatohepatitis (NASH) cirrhosis is an increasingly common indication for liver transplantation (LT) in the United States and obese patients continue to be at…
2019 American Transplant Congress
Blood Group Incompatible Living Donor Kidney Transplantation in Patients with End-Stage Kidney Disease Due to Diabetes Kidney Disease
J. Uchida¹, A. Kosoku¹, K. Kabei¹, S. Nishide¹, H. Shimada¹, K. Maeda², Y. Yoshikawa³, T. Iwai¹, N. Kuwabara¹, T. Naganuma¹, N. Kumada⁴, Y. Takemoto¹, T. Nakatani¹
¹Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Nursing, Osaka City University Hospital, Osaka, Japan, ³Osaka City University, Osaka, Japan, ⁴Urology, Suita Municipal Hospital, Suita, Japan
*Purpose: Diabetes is a growing public health problem, and diabetes kidney disease (DKD) is the most prevalent chronic kidney disease and the major cause of…