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Articles tagged "Hyperglycemia"

  • 2022 American Transplant Congress

    Impact of a Pharmacy-Led Post-Transplant Diabetes Mellitus Clinic in Solid Organ Transplant Recipients

    H. Sweiss1, R. Hall1, M. Flores2, S. Bhayana1, R. Patel1, C. Long2

    1University Health - University Hospital, San Antonio, TX, 2College of Pharmacy, University of Incarnate Word, San Antonio, TX

    *Purpose: To evaluate the impact of a pharmacy-led post-transplant diabetes mellitus (DM) clinic.*Methods: This retrospective chart review from 08/01/20 to 6/30/21 evaluated adult kidney transplant…
  • 2022 American Transplant Congress

    Everolimus versus Mycophenolate in Simultaneous Pancreas and Kidney Transplantation: Progression of Diabetic Retinopathy in a Prospective Randomized Trial

    B. Hagerf1, Z. Hladíková1, M. Zahradnická1, K. Kesslerová2, T. Sosna2, P. Girman1, F. Saudek1

    1Diabetes Centre, IKEM, Prague, Czech Republic, 2Ophtalmology Clinic, Thomayer Hospital, Prague, Czech Republic

    *Purpose: mTOR inhibitors are known for their antiangiogenic effect. We compared the impact of everolimus (E) and mycophenolic acid (MPA) on the course of diabetic…
  • 2022 American Transplant Congress

    Evaluation of GLP-1 Receptor Agonist Use in the Solid Organ Transplant Population

    S. E. Lawrence, M. R. Norvell, K. Schwarz, B. Crowther, P. Klem

    Pharmacy, University of Colorado Hospital, Aurora, CO

    *Purpose: The purpose of this study was to evaluate the utilization of and identify opportunities to optimize the use of glucagon-like peptide-1 receptor agonist (GLP-1…
  • 2022 American Transplant Congress

    Engineered Adaptable Human Endothelial Cells Enable Durable Engraftment of Subcutaneously Transplanted Islets

    R. Craig-Schapiro, G. Li, S. Rafii

    Weill Cornell Medical College, New York, NY

    *Purpose: The current clinical practice of islet transplantation into the portal vein is suboptimal, with reduced vascularization limiting successful engraftment and the inability for monitoring…
  • 2022 American Transplant Congress

    Safety and Efficacy of Glucagon-Like Peptide-1 Receptor Agonists in Solid Organ Transplant

    H. Sweiss1, D. Zeilmann1, J. Escamilla2, R. Hall1, S. Bhayana1, R. Patel1, C. Long2

    1University Health - University Hospital, San Antonio, TX, 2College of Pharmacy, University of Incarnate Word, San Antonio, TX

    *Purpose: To evaluate the safety and efficacy of glucagon-like peptide-1 receptor agonists (GLP1-RA) in solid organ transplant (SOT).*Methods: This retrospective review included adult kidney, liver,…
  • 2021 American Transplant Congress

    The Impact of Diabetes on Young Transplant Recipients: An American Perspective

    J. M. Loera, S. C. Barrett, T. S. Zhang, A. A. Awan, B. V. Murthy, R. T. Cotton, C. A. O'Mahany, N. T. Galvan, J. A. Goss, A. A. Rana

    Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: Our study aims to demonstrate the impact of diabetes, types I and II, on American young adults (18-40 years old) requiring kidney transplantation.*Methods: Using…
  • 2021 American Transplant Congress

    Islet Allotransplantation Into Pre-vascularized Sernova Cell PouchTM – Preliminary Results from the University of Chicago

    P. J. Bachul1, P. E. Borek1, G. S. Generette1, A. Perez-Gutierrez1, K. Jayant1, K. Golab1, L. Basto1, L. Perea1, M. Tibudan1, C. Thomas2, L. Philipson2, J. Fung1, P. Witkowski1

    1Surgery, University of Chicago, Chicago, IL, 2Medicine, University of Chicago, Chicago, IL

    *Purpose: Previous first-in-human pilot study showed safety but the conditions did not allow for detectable islet function post-transplantation into the pre-vascularized Sernova Cell Pouches (SCPs)…
  • 2021 American Transplant Congress

    Insulin Secretion and Insulin Resistance Trajectories Over 1 Year After Kidney Transplantation: A Multicenter Prospective Cohort Study

    B. Jun Bae, C. Oh

    Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of

    *Purpose: We investigated the changing patterns of insulin secretion and resistance and risk factors contributing to the development of post-transplant diabetes mellitus (PTDM) in kidney…
  • 2021 American Transplant Congress

    Prevalence of Diabetic Changes on Kidney Allograft Biopsies of Normoglycemic Simultaneous Pancreas-Kidney Transplant Recipients

    C. Mejia, G. Giannini, D. C. Brennan, A. Rosenberg, S. Alasfar

    Johns Hopkins University, Baltimore, MD

    *Purpose: Small studies suggest that achieving normoglycemia with simultaneous pancreas-kidney transplant (SPK) prevents the development of diabetic nephropathy (DN) among type 1 diabetics (T1DM). However,…
  • 2021 American Transplant Congress

    Transgenic Beta-cell Cxcl12 Expression and Stem Cell Mobilization Synergize to Suppress Type 1 Diabetes

    D. A. Alagpulinsa, A. Jajoo, M. H. Chapin II, M. C. Poznansky

    Vaccine & Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA

    *Purpose: Hematopoietic stem and progenitor cells (HSPCs) and regulatory T cells (Tregs) highly express CXCR4, the receptor for the CXCL12 chemokine. This keeps them predominantly…
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