Articles tagged "HMG-CoA reductase inhibitor"

2021 American Transplant Congress
Impact of Statin Intensity on the Incidence of Vascular Events and Graft Survival in Heart Transplant Recipients
E. Kim¹, I. Booth², R. Madathil³, B. Ravichandran¹, M. Demehin², M. Plazak²
¹University of Maryland School of Pharmacy, Baltimore, MD, ²Pharmacy, University of Maryland Medical Center, Baltimore, MD, ³University of Maryland School of Medicine, Baltimore, MD
*Purpose: Cardiac allograft vasculopathy (CAV) limits long-term graft survival of heart transplant (HT) recipients. In addition to decreased synthesis of cholesterol, statins also demonstrate immunomodulatory…
2020 American Transplant Congress
Taking it to the Max: Extremely Low LDL May Provide Benefit for Prevention of Cardiac Allograft Vasculopathy
R. Lee¹, E. J. Henricksen¹, Y. Moayedi², K. Y. Feng³, J. Han³, W. Yang⁴, R. Imai¹, J. J. Teuteberg⁴, K. K. Khush⁴
¹Pharmacy, Stanford Health Care, Stanford, CA, ²University Health Network, Toronto, ON, Canada, ³Medicine, Stanford University, Stanford, CA, ⁴Cardiac Transplant, Stanford University, Stanford, CA
*Purpose: Routine use of statins is the only Class I ISHLT recommendation in heart transplantation (HT) to reduce cardiac allograft vasculopathy (CAV) and improve survival.…
2019 American Transplant Congress
Statin Underutilization in Patients Listed for Liver Transplant
K. Mishra¹, S. Naffouj¹, S. Modi¹, C. Dagher¹, S. Gorgis¹, D. Venkat²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Transplant Hepatology, Henry Ford Hospital, Detroit, MI
*Purpose: Current guidelines recommend statin use in high risk patients based on the ASCVD (atherosclerotic cardiovascular disease) score, diabetes, or LDL levels. Despite several trials…
2016 American Transplant Congress
Eary Use of Statins Associated with Improved Death-Censored Graft Survival Following Kidney Transplant.
T. Horwedel,¹ D. Brennan,² K. Lentine,³ J. Hagopian.¹
¹Barnes-Jewish Hospiptal, St. Louis, MO; ²Washington University School of Medicine, St. Louis, MO; ³St. Louis University, MO.
Purpose: The impacts of statin therapy on patient and graft outcomes after kidney transplantation (KT) are controversial.Methods: We performed a retrospective cohort study of adult…