2017 American Transplant Congress
Early Rejection in the Elderly: Is It Predictable?
University of Maryland Medical Center, Baltimore, MD
Introduction: Optimal induction for elderly kidney transplant recipients (KTR) remains unclear. Older age may be associated with decreased immunogenicity; however, clinical heterogeneity of the elderly…2017 American Transplant Congress
HLA Mismatching Does Not Have an Impact on Graft or Patient Survival in Simultaneous Kidney-Pancreas Transplantation. A Single Institution Experience.
Indiana University Health, Indianapolis
Purpose: There is conflicting data on whether the level and type of HLA mismatching (MM) has an impact on pancreas, kidney, or patient survival in…2017 American Transplant Congress
Effect of HLA-DQ Mismatch on Efficacy Outcomes and Renal Function in Kidney Transplant Recipients: Subanalysis from the ELEVATE Study.
1ELEVATE Study Group, Köln, Germany; 2Novartis Pharma AG, Basel, Switzerland
Purpose: Human leukocyte antigen (HLA)-DQ mismatches are often associated with acute rejection, independent of mismatches at other loci. Previous analysis from the ELEVATE (NCT01114529) study…2017 American Transplant Congress
Renal Function Outcomes by HLA Mismatch in De Novo Kidney Transplant Recipients Receiving Everolimus PlusReduced-Dose Cyclosporine versus Mycophenolate Plus Standard-Dose Cyclosporine: 24-Month Subanalysis of A1202 Study.
Purpose: High levels of human leukocyte antigen (HLA) mismatches are a key determinant of kidney allograft survival. Here, we present 24-month (M) subanalysis of the…2017 American Transplant Congress
The Outcome of 0 Mismatch Kidney in Pediatric Population with High Immunologic. The Impact of Induction Therapy. An Analysis of UNOS Database.
Surgery, State University New York, Syracuse, NY
Background: 0 mismatch kidneys have superior outcomes in primary transplant recipient. We performed Analysis UNOS database to determine the outcome of high PRA transplant pediatric…2017 American Transplant Congress
Kidney Transplant Rejection Associated with DQ Eplet Mismatches.
The presence of anti-HLA antibodies is associated with acute rejection, allograft dysfunction and earlier graft loss. HLA antibodies are recognized as being specific to these…2017 American Transplant Congress
Graft-versus-Host Disease Following Deceased Donor Liver Transplant.
Henry Ford Hospital, Detroit, MI
We reviewed our institutional experience with graft-versus-host disease (GVHD) following orthotopic liver transplantation (OLT). All OLT from 10/1/2013-10/1/2016 were reviewed. Five cases of GVHD were…2017 American Transplant Congress
Zero HLA Mismatch Matters in ABO Incompatible Kidney Transplant.
1Washington University in St. Louis, St. Louis; 2Saint Louis University, St. Louis
Transplantation across blood group incompatibilities (ABOi) after preconditioning has emerged as an acceptable option for expanding live donor kidney transplantation (LKDT) to more patients who…2017 American Transplant Congress
HLA Eplet Mismatches Predict DSA Formation, Graft Survival, and Re-Transplantation Rate in Pediatric Renal Transplantation.
The potential benefits of HLA epitope based matching are greatest for pediatric recipients, however, there is little published data on the association of epitope mismatches…2017 American Transplant Congress
HLA-C Mismatching and Humoral Alloimmune Responses in Pediatric Kidney Recipients with Subclinical Vascular Injury.
University of Alabama at Birmingham, Birmingham, AL
Background: Antibodies to mismatched donor HLA antigens (DSA) have been associated with poor long-term outcomes in adult kidney recipients. We recently demonstrated a high prevalence…
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