ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "HLA matching"

  • 2018 American Transplant Congress

    MICA/B Polymorphisms and the Relationship of the Matching Degree between MICA/B and HLA of Related Donor-Recipient Pairs in Allo-HSCT

    Y. Sun, Y. Hao, J. Jin, L. Ding, F. Liang, N. Liu, J. Long, X. Zhao, Y. Xi.

    Beijing 307 Hospital, Beijing, China.

    Objective: To explore the distribution characteristics of MICA/B gene polymorphism in the Han Chinese and the relationship of the matching degree between MICA/MICB and HLA…
  • 2018 American Transplant Congress

    Mycophenolate Monotherapy is Safe and Effective in HLA-Matched Kidney Transplant Recipients

    A. Hennes, K. Holdener, W. Burlingham, B. Astor, A. Djamali.

    UW Health, Madison, WI.

    Purpose: The ideal minimizing strategy for maintenance immunosuppression in HLA-matched kidney transplant recipients (KTR) is unknown. We hypothesized that mycophenolate (MPA) monotherapy is a safe…
  • 2018 American Transplant Congress

    HLA Mismatching and cPRA Do Not Affect BK Viremia and Nephropathy Risk in Kidney Transplantation: A Retrospective Analysis

    B. Suleiman, S. Saleh, W. Hassan, K. Wang, A. Maibam, A. Karim, A. Hines, X. Mei, A. El-Husseini, M. Yaseen, V. Cornea, A. Castellanos, R. Gedaly, T. Waid.

    Nephrology, University of Kentucky, Lexington, KY.

    Introduction:Nephropathy from BK virus is a significant complication of kidney transplantation and occurs following a period of viremia. Patients who are HLA mismatched and more…
  • 2018 American Transplant Congress

    Shortened Cold Ischemia Time and Reduced Incidence of Delayed Graft Function for Kidney Transplants through Enhanced Tissue Compatibility Testing

    I. Helanterä,1 T. Saarinen,2 J. Peräsaari,2 M. Lempinen,1 J. Lauronen.2

    1Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland; 2Histocompatibility Laboratory, Finnish Red Cross Blood Service, Helsinki, Finland.

    A. HLA-typing and prospective leukocyte cross-matching needed for deceased donor kidney transplantation (kTX) may delay the onset of surgery. We compared cold ischemia times (CIT)…
  • 2018 American Transplant Congress

    Epitope/Eplet Mismatch in Pediatric Renal Transplantation and Development of Donor Specific Antibody

    R. George,1 H. Sullivan,2 R. Garro,1 P. Winterberg,1 B. Warshaw,1 H. Gebel,2 R. Bray.2

    1Pediatric Nephrology, Emory University & Children's Healthcare of Atlanta, Atlanta, GA; 2Dept. of Pathology, Emory Transplant Center, Emory University, Atlanta, GA.

    Background: De-novo donor specific antibody (DSA) is one of the strongest independent predictors of graft loss with HLA mismatching being a major risk factor for…
  • 2018 American Transplant Congress

    Feasibility of a National Class II Matching Strategy for Pediatric Kidney Transplant Candidates

    T. Blydt-Hansen,1 W. Klement,2 K. Tinckam,3 J. Gill.1

    1University of British Columbia, Vancouver, Canada; 2Canadian Blood Services, Ottawa, Canada; 3University of Toronto, Toronto, Canada.

    Antibody-mediated rejection (AMR) is a major concern for allograft failure, which could be mitigated by allocation of Class II matched donors. Since children have priority,…
  • 2018 American Transplant Congress

    High Frequency of HLA-DQ De Novo Donor Specific Antibodies is Independent of the Number of Mismatches in Heart Transplant

    X. Zhang,1 E. Kransdorf,2 J. Patel,2 J. Kobashigawa.2

    1HLA and Immunogenetics Laboratory/ Comprehensive Transplant Center, Cedars-Sinai Health Systems, Los Angeles, CA; 2Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA.

    Aim: Development of de novo donor specific antibodies (DSA) after heart transplant is associated with an increased risk of allograft failure. The aim of this…
  • 2017 American Transplant Congress

    Effects of New KPD Histocompatibility Policy on Refusal Rate and Transplants.

    R. Leishman,1 M. Aeder,2 M. Leffell,3 C. Murphey,4 N. Reinsmoen,5 S. Saidman,6 T. Sandholm,7 A. Toll,1 A. Harper,1 N. Turgeon.8

    1UNOS, Richmond, VA; 2Univ Hosp Med Ctr, Cleveland, OH; 3Johns Hopkins Univ, Baltimore, MD; 4SW Immunodiagnostics, San Antonio, TX; 5Cedars-Sinai Health, Los Angeles, CA; 6Mass Gen Hosp, Boston, MA; 7Carnegie Mellon Univ, Pittsburgh, PA; 8Emory Univ, Atlanta, GA

    Background: Transplant centers commonly refuse kidney paired donation (KPD) match offers due to unacceptable crossmatch (XM). To reduce XM refusals a new OPTN KPD histocompatibility…
  • 2017 American Transplant Congress

    The New Kidney Allocation System in France Meets it's Targets: Improving Age and HLA DR-QD Matching for Young Adults.

    C. Jacquelinet, B. Audry, F. Bayer, M. Macher.

    Direction Medicale et Scientifique, Agence de la Biomedecine, Saint-Denis, France

    A new KAS was implemented in France as of February 2015, resulting from an intensive 3 yrs-simulation work in interaction with KTx advisory committee and…
  • 2017 American Transplant Congress

    Development of De Novo Donor Specific Antibodies (dnDSAs) Not the Presence of Pre-Transplant Donor Specific Antibodies (Pre-DSAs) Increase Rejection Risk in Crossmatch Negative Kidney Transplant Recipients.

    H. Khamash, L. Archambault, M. Buras, H. Kosiorek, M. Pando, K. Reddy, B. Kaplan, R. Heilman.

    Mayo Clinic Arizona, Phoenix, AZ

    Aim: Study the impact of Pre-DSAs on allograft outcomes in crossmatch negative kidney transplant recipients.Methods: Single center retrospective analysis of characteristics and outcomes of kidney…
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