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Articles tagged "HLA matching"

  • 2019 American Transplant Congress

    Predictors and Outcomes of Acute Graft-versus-Host Disease after Liver Transplant

    A. Caines1, S. Nagai2, R. Salgia1

    1Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI, 2Transplant Surgery, Henry Ford Health System, Detroit, MI

    *Purpose: Graft-versus-Host Disease (GVHD) is a rare complication of liver transplant (LT) that has an estimated incidence of 0.1%-2% per year and is associated with…
  • 2019 American Transplant Congress

    Development of a Recurrence Risk Score in IgA Nephropathy after Kidney Transplantation: Role of Recipient Age and HLA-B Mismatch

    L. M. Rodas Marin1, E. Ruiz2, A. García3, M. Blasco1, P. Ventura1, E. de Soussa1, O. Viñas4, F. Diekmann1, L. Quintana1

    1Nephrology and Renal Trasplantation, Hospital Clinic, Barcelona, Spain, 2Immunology, Hospital Clinic, Barcelona, Spain, 3Pathology, Hospital Clinic, Barcelona, Spain, 4Inmunology, Hospital Clinic, Barcelona, Spain

    *Purpose: Recurrence of IgA nephropathy is an important and growing cause of kidney allograft dysfunction. The purpose of this observational retrospective study was to characterize…
  • 2019 American Transplant Congress

    Comparative Analysis of Belatacept and Mycophenolate Monotherapy-Based Regimens for HLA Identical Living Donor Kidney Transplantation

    M. Yamada, K. Meganathan, A. Shields, P. Brailey, S. Tremblay, A. Govil, R. R. Alloway, S. Shah, E. S. Woodle, B. G. Abu Jawdeh

    Univ. of Cincinnati, Cincinnati, OH

    *Purpose: HLA identical (HLA ID) living donor kidney transplants (KTx) provide long-term survival with substantially reduced rejection risk; aspects that can be exploited in designing…
  • 2019 American Transplant Congress

    Severe Acute Rejection In Human Leukocyte Antigen Identical Renal Transplants: Reviving Mixed Lymphocyte Culture

    P. Rajendran1, M. Cusick2, S. Dhingra3, B. Murthy1

    1Baylor College of Medicine, Houston, TX, 2Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, 3Pathology, Baylor College of Medicine, Houston, TX

    *Purpose: Human leukocyte antigen-identical renal transplants among siblings account for a minority of all renal transplants, but have excellent long-term outcomes due to very minimal…
  • 2019 American Transplant Congress

    Transplant Nephrologist

    K. A. AlMeshari1, D. Broering2, I. Alahmadi3, S. Raza3, T. Ali3, F. Alzayer4, A. Algharabli4

    1King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 2Organ Transplant Center, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 3Kidney & Pancreas Transplantation Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 4Department of Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

    *Purpose: Matching rates of very highly sensitized patients with cPRA of 91 - 100% (VHSP) and blood type O recipients of ABO incompatible donors (ABO…
  • 2019 American Transplant Congress

    Specific Donor/Recipient HLA Disparities are Associated with Better Long-Term Kidney Allograft Survival among 4-, 5-, and 6-HLA (A/B/DR)-Mismatched Pairs

    D. Bekbolsynov, H. Zhang, B. Mierzejewska, M. Rees, K. Xu, S. Stepkowski

    University of Toledo, Toledo, OH

    *Purpose: The vast majority of deceased donor kidneys are allocated without any consideration for the HLA disparities, which may improve or worsen the survival the…
  • 2019 American Transplant Congress

    Human Leukocyte Antigen Class I (HLA-I) Antibodies in Patients Undergoing Liver Transplantation: Implications for Platelet Transfusion Support

    M. Wong1, R. Narra2, M. Selim1, M. A. Zimmerman1, A. Padmanabhan3, J. C. Hong1

    1Div. of Transplant Surgery, Medical College of Wisconsin, Milwaukee, WI, 2Div. of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, 3Medical College of Wisconsin and BloodCenter of Wisconsin, Milwaukee, WI

    *Purpose: Liver transplantation is a high platelet transfusion (PLT) setting due to the elevated incidence of thrombocytopenia and bleeding. HLA-I antibodies are thought to have…
  • 2019 American Transplant Congress

    The Impact of Eplet Mismatches on Kidney Transplant Outcome: A Single-Center Cohort Study

    A. Senev1, M. Coemans1, V. Van Sandt2, B. Sprangers3, D. Kuypers3, M. Emonds2, M. Naesens3

    1Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium, 2Histocompatibility and Immunogenetics Laboratory, Belgian Red Cross-Flanders, Mechelen, Belgium, 3University Hospitals Leuven, Leuven, Belgium

    *Purpose: It has been shown that HLA-matching at classic antigen-level for HLA-A, -B and -DRB1 loci, provides benefits in matching and outcome after solid organ…
  • 2019 American Transplant Congress

    Effect of Human Leukocytic Antigen Matching on Clinical Outcomes after Deceased Donor Renal Allograft Transplant: A Single Centre Experience

    M. E. Gramlick1, M. K. Heer2, S. Yausis2, P. R. Trevillian2

    1Department of Surgery, John Hunter Hospital, Newcastle, Australia, 2Newcastle Transplant Unit, John Hunter Hospital, Newcastle, Australia

    *Purpose: Human leucocyte antigen (HLA) matching has been the cornerstone of kidney allocation policies. With increasing expertise in assessing and managing immunological risks, the impact…
  • 2019 American Transplant Congress

    DR53, You Can’t See Me: A Deceased Donor Tale of Ambiguous Typing

    S. Dionne1, S. Shetty1, L. Santiago1, K. Klama2

    1VRL Eurofins, Centennial, CO, 2VRL Eurofins, Philadelphia, PA

    *Purpose: Our laboratory performs STAT HLA typing for an OPO using RT-PCR methodology. A 46 year old, male Caucasian deceased donor was worked up by…
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