2019 American Transplant Congress
Comparative Analysis of Belatacept and Mycophenolate Monotherapy-Based Regimens for HLA Identical Living Donor Kidney Transplantation
Univ. of Cincinnati, Cincinnati, OH
*Purpose: HLA identical (HLA ID) living donor kidney transplants (KTx) provide long-term survival with substantially reduced rejection risk; aspects that can be exploited in designing…2019 American Transplant Congress
Severe Acute Rejection In Human Leukocyte Antigen Identical Renal Transplants: Reviving Mixed Lymphocyte Culture
*Purpose: Human leukocyte antigen-identical renal transplants among siblings account for a minority of all renal transplants, but have excellent long-term outcomes due to very minimal…2019 American Transplant Congress
Transplant Nephrologist
*Purpose: Matching rates of very highly sensitized patients with cPRA of 91 - 100% (VHSP) and blood type O recipients of ABO incompatible donors (ABO…2019 American Transplant Congress
Specific Donor/Recipient HLA Disparities are Associated with Better Long-Term Kidney Allograft Survival among 4-, 5-, and 6-HLA (A/B/DR)-Mismatched Pairs
University of Toledo, Toledo, OH
*Purpose: The vast majority of deceased donor kidneys are allocated without any consideration for the HLA disparities, which may improve or worsen the survival the…2019 American Transplant Congress
Human Leukocyte Antigen Class I (HLA-I) Antibodies in Patients Undergoing Liver Transplantation: Implications for Platelet Transfusion Support
*Purpose: Liver transplantation is a high platelet transfusion (PLT) setting due to the elevated incidence of thrombocytopenia and bleeding. HLA-I antibodies are thought to have…2019 American Transplant Congress
The Impact of Eplet Mismatches on Kidney Transplant Outcome: A Single-Center Cohort Study
*Purpose: It has been shown that HLA-matching at classic antigen-level for HLA-A, -B and -DRB1 loci, provides benefits in matching and outcome after solid organ…2019 American Transplant Congress
Effect of Human Leukocytic Antigen Matching on Clinical Outcomes after Deceased Donor Renal Allograft Transplant: A Single Centre Experience
*Purpose: Human leucocyte antigen (HLA) matching has been the cornerstone of kidney allocation policies. With increasing expertise in assessing and managing immunological risks, the impact…2019 American Transplant Congress
DR53, You Can’t See Me: A Deceased Donor Tale of Ambiguous Typing
1VRL Eurofins, Centennial, CO, 2VRL Eurofins, Philadelphia, PA
*Purpose: Our laboratory performs STAT HLA typing for an OPO using RT-PCR methodology. A 46 year old, male Caucasian deceased donor was worked up by…2019 American Transplant Congress
Impact of Induction Choice and Early Steroid Withdrawal on Outcomes in HLA Zero Mismatched Kidney Transplant Recipients
*Purpose: Ideal induction and immunosuppression therapy for 6-antigen HLA matched deceased and living kidney transplant recipients (KTR) is not well understood.*Methods: All 6-antigen HLA matched…2019 American Transplant Congress
Impact of HLA-DR Matching on HLA-DQ Matching Status and the Development of Anti-HLA-DQ De Novo DSA under Calcineurin Inhibitor or Belatacept Immunosuppression
*Purpose: De novo donor-specific HLA antibodies (dnDSA) that develop after kidney transplantation target more frequently allo-HLA-DQ antigens in comparison to other allo-HLA antigens. Yet, organ…
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