2021 American Transplant Congress
Low Immunogenic Donors Improved Survival of Kidney Transplants in African American Recipients
1University of Toledo, Toledo, OH, 2Bowling Green State University, Bowling Green, OH
*Purpose: Kidney transplants fail more often in African American (AA) than in Caucasian (CAU) recipients. We calculated the hydrophobic mismatch score (HMS) from polymorphic amino…2021 American Transplant Congress
hlaR,” a Simplified Interface for the HLA Matchmaker Tool
1Surgery, Emory University, Atlanta, GA, 2Pathology, Emory University, Atlanta, GA
*Purpose: Functional epitopes, or eplets, represent a set of amino acids within three angstroms of one another that may not be sequentially contiguous but are…2020 American Transplant Congress
HLA Diversity Affects Epitope Mismatch Cutoffs Utilized to Predict De Novo DSA Development and Graft Rejection in Renal Transplant Patients
*Purpose: Recent studies have investigated epitope matching in order to determine its predictive power in determining renal transplant outcomes, both in terms of de novo…2020 American Transplant Congress
Eplet Mismatch Imputed from HLA Serotype-Level Data Can Improve Risk Stratification for Kidney Allograft Loss
*Purpose: HLA-Epitope mismatch improves risk stratification following kidney transplantation. Based on population data, high resolution HLA types required for epitope prediction can be imputed based…2020 American Transplant Congress
Is the Epitope Mismatch Load Enough to Identify HLA-DQ Mismatches with a Low Risk for De Novo DSA Development?
*Purpose: The development of de novo donor-specific anti-HLA antibodies (dnDSA) remains a major risk factor for poor long-term kidney allograft outcomes. In particular, anti-HLA-DQ dnDSAs,…2020 American Transplant Congress
Improving Access to Transplantation and Outcomes for African American Patients
University of Toledo, Toledo, OH
*Purpose: Black or African American patients are clearly disadvantaged in comparison to Caucasian patients both in terms of the access to kidney transplantation and post-transplant…2020 American Transplant Congress
Failure to Launch; a Multi-Centre Study of Potential Live Donors in Southeast Nigeria
*Purpose: To determine the socio-demographic characteristics of potential living kidney donors, donor motivation, incidental findings on clinical evaluation and some identified factors that precluded eventual…2020 American Transplant Congress
The Clinical Relevance of cPRA in 0-ABDRDQ Mismatched Kidney Transplants
*Purpose: The clinical relevance of immune sensitization as measured by cPRA in kidney transplantation remains uncertain.*Methods: We identified 4,057 adult, first, kidney only transplant recipients…2020 American Transplant Congress
Compatible Pairs- Providingan Option to Upgrade
*Purpose: Compatible pairs (CPs) can enter an exchange program instead of donating directly. These pairs increase transplants (txp) by providing additional donors within an exchange…2020 American Transplant Congress
Noninvasive Genotyping of Donor’s HLA in Kidney Transplant Patients by Target Capture Sequencing
AlloDx, Shanghai; Suzhou, China
*Purpose: Antibody-mediated rejection (ABMR) is the major cause of kidney transplant failure, which requires donor-specific antibodies (DSA) for a definitive diagnosis based on Banff 2013.…
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