2015 American Transplant Congress
Highly Accurate High-Resolution HLA Imputation Using Dense Genotyping Data
HLA similarity between donors (D) and recipients (R) of solid organ transplantation (SOT) plays a central role in determining the risk of rejection or graft-versus-host…2015 American Transplant Congress
HLA Matching Affects Patient Survival, Graft Survival, and Incidence of Rejection Episodes in Largest Analysis to Date
Introduction: Though human leukocyte antigen (HLA) matching between donor and recipient affects both graft and patient survival after kidney and heart transplantation, prior analysis has…2015 American Transplant Congress
A Single Centre Experience With the Living Donor Kidney Sharing Scheme: More Is Better!
Oxford Transplant Centre, Oxford University Hospitals, Oxford, Berkshire, United Kingdom.
Introduction: The living donor kidney sharing scheme was introduced in the UK to expand the donor pool. In this study we have reviewed our experience…2015 American Transplant Congress
Do Induction Therapy, Patient-Level and Post-Operative Factors Impact Outcomes in Moderate to High Immunologic Risk Simultaneous Kidney-Pancreas Transplantation in the Era of Stringent HLA Cross-Matching?
Background: Simultaneous kidney and pancreas transplantation (SPK) is a lifesaving procedure for patients with diabetes mellitus. The success of SPK is dependent upon minimization of…2015 American Transplant Congress
Impact of Pretransplant Pregnancy On Immunization and Immunologic Outcome in Kidney Transplantation
BACKGROUND:The detailed impact of pretransplant pregnancy on HLA alloimmunization and outcome after kidney transplantation is so far not well known.PATIENTS AND METHODS:A retrospective single center…2015 American Transplant Congress
HLA-Cw Mismatches Are Not Associated With Worse Graft Outcomes After Kidney Transplantation Even in High Levels of Antigen Expression
1Cleveland Clinic, Cleveland; 2University of Alexandria, Alexandria, Egypt.
The HLA-Cw antigens are distinct in having relatively lower expression on the cell surface compared to the other HLA class I loci. Higher HLA Cw…2015 American Transplant Congress
Human Leukocyte Antigen Mismatch and Steroid Maintenace in Kidney Transplantation
Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.
Kidney transplant recipients (KTRs) with zero/minimal HLA mismatches against their donors enjoy superior long term outcomes related to diminished immune response of the recipient against…2015 American Transplant Congress
“Unexpected” Positive Crossmatchs in Zero-HLA-A-B-DR Mismatched or HLA-DR-Matched Organs
Deceased donor kidney allocation is currently prioritized by HLA-A,-B and-DR serologic matching, which disregards both specificity at the allele level, and the contributions of HLA-C,-DQ,…
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