2017 American Transplant Congress
Validation of a Novel Computational Approach for Predicting HLA Immunogenicity Based on Quantification of Structural and Surface Electrostatic Potential Differences Between Donor and Recipient HLA.
Background: Our preliminary work indicates that donor HLA immunogenicity in kidney and haematopoietic stem cell transplantation can be predicted by comparative assessment of donor and…2017 American Transplant Congress
Outcome of Systemic Monitoring of DSA and Protocol Management to Optimize Renal Allograft Outcome in a Single Transplant Center.
Denovo (dn) donor specific antibody (DSA) development has been shown to adversely affect long-term allograft survival. To improve graft outcome for kidney (K) transplant (Tx)…2017 American Transplant Congress
Acute Rejection in 6 Antigen HLA Matched Kidney Transplant Recipients: Risk Factors and Outcomes.
University of Wisconsin Health, Madison, WI
Background: Acute rejection in HLA matched kidney transplant recipients is uncommon, and the mechanisms involved are not well understood.Methods: Data from 6 antigen HLA matched…2017 American Transplant Congress
Early Rejection in the Elderly: Is It Predictable?
University of Maryland Medical Center, Baltimore, MD
Introduction: Optimal induction for elderly kidney transplant recipients (KTR) remains unclear. Older age may be associated with decreased immunogenicity; however, clinical heterogeneity of the elderly…2016 American Transplant Congress
Donor Specific Antibody Used to Predict Crossmatch Results: A Clinically Useful Algorithm Derived from the College of American Pathologists Survey.
Purpose: While there are multiple modalities to perform a preoperative crossmatch for organ transplant surgery, the cytotoxic crossmatch remains the gold standard for detection of…2016 American Transplant Congress
Improving Kidney Allocation System with Higher Resolution.
Northwestern University, Chicago, IL.
Purpose: The new kidney allocation system (KAS) was implemented to help identify compatible donors for the most highly sensitized patients. Our experience, as well as…2016 American Transplant Congress
Presence of Highly Immunogenic Mismatch Eplets Is Associated with Development of Chronic Active Antibody-Mediated Rejection: A First Report from Japan.
Urology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
Backgrounds: De novo donor specific antibody (dnDSA) correlates with chronic active antibody-mediated rejection (CAAMR), a major leading cause of graft loss. It will be a…2016 American Transplant Congress
Protective Impact of the Kidney in SPK Transplants – Mechanisms for Improved Outcomes Compared with Solitary Transplants.
Surgery, University of Minnesota, Minneapolis, MN.
Purpose: Outcomes for SPK txps are superior to solitary pancreas txps. The basis for this difference is unknown. We sought to identify the biologic mechanism…2016 American Transplant Congress
Epitope Load Is Predictive of De Novo Donor Specific Antibodies Occurrence in Renal Transplant Recipients After Conversion from Cyclosporine to Everolimus.
IntroductionThe degree of HLA compatibility between donor and recipient is an important risk factor of developing de novo DSA, but misjudged by the number of…2016 American Transplant Congress
Immunogenic HLA-DR Eplet Mismatches as Predictors of Transplant Glomerulopathy.
BackgroundThe number of HLA-DR eplet mismatches (eplet load) is a risk factor for the development of anti-HLA antibodies and transplant glomerulopathy (TG). In the case…
- « Previous Page
- 1
- …
- 8
- 9
- 10
- 11
- 12
- Next Page »