ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "HLA matching"

  • 2022 American Transplant Congress

    Understanding The Modification Of Eplet Mismatch Risk By Immunosuppression Regimen

    A. Johnson1, X. Zhang1, L. Gragert2, C. Larsen1

    1Emory University School of Medicine, Atlanta, GA, 2Tulane University School of Medicine, New Orleans, LA

    *Purpose: Solid organ transplant donor-recipient eplet mismatch has been correlated with subsequent donor specific antibody (DSA) formation, antibody mediated rejection, and overall rejection rates. However,…
  • 2022 American Transplant Congress

    The Effects of Race-Matching in Small Intestine Transplantation

    C. G. Yergin1, C. Warren2, S. Duarte3, T. Beduschi4, A. Zarrinpar5

    1College of Medicine, University of Florida, Gainesville, FL, 2-, -, AL, 3University of Florida, Gainesville, FL, 4Department of Surgery, University of Florida, Gainesville, FL, 5University of California Los Angeles, Gainesville, FL

    *Purpose: We sought to investigate whether race-matching in small intestine (SI) transplantation correlates with better transplantation outcomes, as well as lower odds of graft rejection.*Methods:…
  • 2022 American Transplant Congress

    Improving Value Delivery in Compatible Living Donor Kidney (CLD) Transplant Through Zero-Low Eplet Mismatch via National Kidney Registry (NKR)

    S. Anand1, J. Sanchez-Garcia1, W. Stapley1, J. Browning1, M. Egbert1, S. Dow1, A. Raza1, T. Srinivas2, D. Morris1

    1Intermountain Medical Center, Murray, UT, 2CareDX, South San Francisco, CA

    *Purpose: Despite advances in diagnostics and therapeutics, kidney allograft survival rates have not increased considerably. Kidney For Life (KFL) through NKR aims to increase access…
  • 2022 American Transplant Congress

    Does Black Race Modify the Risk of Transplant Failure Associated with HLA Mismatch in First Adult Kidney Allografts from Deceased Donors?

    K. Atiemo

    Tulane University, New Orleans, LA

    *Purpose: Current US- based data suggests Black patients awaiting kidney re-transplantation are more likely to be highly sensitized compared to other races. Degree of HLA…
  • 2022 American Transplant Congress

    HLA-DQ Mismatches Are More Likely to Be Listed as Unacceptable Antigens After Renal Graft Failure in African American Recipients as Compared to Other Racial/Ethnic Groups

    D. Isaacson1, M. W. Gmeiner2, V. Kosmoliaptsis3, J. D. Schold4, A. R. Tambur1

    1Northwestern University, Chicago, IL, 2London School of Economics, London, United Kingdom, 3Cambridge University, Cambridge, United Kingdom, 4Cleveland Clinic, Cleveland, OH

    *Purpose: Growing evidence suggests that donor-recipient mismatches at the HLA-DQ locus are the most immunogenic and pathogenic, evidenced by generation of DQ donor-specific antibodies (DSA).…
  • 2022 American Transplant Congress

    Impact of HLA Matching on Graft Survival in Kidney Transplant Recipients

    J. Miller1, N. Salkowski1, B. Thompson1, R. Kandaswamy2, P. Stock3, A. Israni1

    1Scientific Registry of Transplant Recipients, Minneapolis, MN, 2Department of Surgery, University of Minnesota Medical School, Minneapolis, MN, 3Department of Surgery, University of California San Francisco, San Francisco, CA

    *Purpose: This study aims to estimate the association of HLA matching at the A, B, DR, and DQ loci with posttransplant graft failure and patient…
  • 2022 American Transplant Congress

    Allo-Sensitization is Increased in Liver Transplant Recipients Following Ischemia-Reperfusion Injury

    R. A. Sosa, A. Q. Terry, Y. Yin, B. V. Naini, F. M. Kaldas, R. W. Busuttil, D. W. Gjertson, J. W. Kupiec-Weglinski, E. F. Reed

    UCLA, Los Angeles, CA

    *Purpose: Recipient sensitization to donor HLA antigens remains an important clinical problem in transplantation, leading to increased wait times to find a compatible donor and…
  • 2022 American Transplant Congress

    Concurrent Use of Two Methods Prevents Erroneous HLA Typing of Deceased Organ Donors – An Essential Strategy for Patient Safety and Accurate Virtual Crossmatching for Broader Sharing

    R. Rajalingam, T. dela Cruz, C. Dames, L. Pagaduan, Y. Cho, D. Kong

    Immunogenetics and Transplantation Laboratory (ITL), University of California San Francisco, San Francisco, CA

    *Purpose: Comprehensive and accurate typing for ever-increasing alleles of all eleven HLA genes within a short turnaround time is a crucial initial step for allocating…
  • 2022 American Transplant Congress

    Performance of Kidney Transplantation in a Resource-Poor Setting of Southeast Nigeria- A Review of the First Ten Cases

    C. G. Okwuonu1, O. J. Chimezie2, G. O. Achor3, N. M. Erondu4, C. Ralph-Iheke5, S. Alhassan6

    1INTERNAL MEDICINE/NEPHROLOGY, Federal Medical Centre, Umuahia, Nigeria, 2OPTOMETRY, Federal Medical Centre, Umuahia, Nigeria, 3SURGERY/UROLOGY, Federal Medical Centre, Umuahia, Nigeria, 4ANAESTHESIA, Federal Medical Centre, Umuahia, Nigeria, 5NURSING SERVICES DIVISION, Federal Medical Centre, Umuahia, Nigeria, 6SURGERY/UROLOGY, Aminu Kano Teaching Hospital, Kano, Nigeria

    *Purpose: To assess complication and survival after performance of kidney transplantation in a resource poor setting in Southeast Nigeria*Methods: A retrospective review of transplant registers…
  • 2022 American Transplant Congress

    HLA DSA May Not Be Detected in Many Solid Organ Recipients

    J. C. Quon1, R. M. Lestz2, J. Menteer2, N. Fotiadis2, L. A. Baxter-Lowe2

    1Keck School of Medicine, Los Angeles, CA, 2Children's Hospital Los Angeles, Los Angeles, CA

    *Purpose: Clinically significant HLA antibodies may not be detected if their unique HLA epitopes are not represented in the single antigen reagents that are routinely…
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