2019 American Transplant Congress
DR53, You Can’t See Me: A Deceased Donor Tale of Ambiguous Typing
1VRL Eurofins, Centennial, CO, 2VRL Eurofins, Philadelphia, PA
*Purpose: Our laboratory performs STAT HLA typing for an OPO using RT-PCR methodology. A 46 year old, male Caucasian deceased donor was worked up by…2019 American Transplant Congress
Influence Of HLA-DR Mismatches On Long Term Outcomes Following Heart Transplantation
Division of Cardiology/ JC Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX
*Purpose: In the field of kidney transplantation, there is strong support for the beneficial effect of minimizing donor-recipient HLA incompatibility, and HLA-DR matching in particular…2019 American Transplant Congress
Kidney Transplantation in Older Recipients with HLA-DR Mismatch: Impact of Induction Type on Outcomes
*Purpose: In kidney transplantation, donor-recipient HLA-DR mismatch signals high immunologic risk and can result in poor transplant outcomes. Older kidney transplant recipients (KTRs) are more…2019 American Transplant Congress
HLA-DR Upregulation in Pediatric Kidney Transplant Biopsies
Medical University of South Carolina, Charleston, SC
*Purpose: Renal tubular epithelial cells do not typically express human leukocyte antigen DR (HLA-DR). It’s expression has been associated with different types of tubular injury…2018 American Transplant Congress
HLA-DR4 Matching and Hepatocellular Carcinoma Recurrence after Liver Transplantation
PURPOSE: The phenomenon of graft versus host disease after orthotopic liver transplantation (OLT) is estimated at approximately 1-2%, suggesting that under some circumstances, the graft…2018 American Transplant Congress
Impact of Steroid Maintenance on the Outcomes of HLA-DR Mismatch Kidney Transplantation
Allegheny General Hospital, Pittsburgh, PA.
In kidney transplantation, donor-recipient HLA-DR mismatch poses high immunologic risk and is associated with inferior outcomes. We aimed to explore the impact of enhanced immunosuppression…2017 American Transplant Congress
HLA-DR Based Murine Transplant Model for Studying Collagen Type V Autoimmunity in Chronic Allograft Rejection.
Dept. of Surgery/Transplant Division, UW Madison, Madison, WI
Background: In lung and heart transplant patients, chronic rejection manifests as fibro-obliteration of airways and vessels resulting in bronchiolitis obliterans syndrome (BOS) or cardiac allograft…2016 American Transplant Congress
Impact of HLA-DR Compatibility on Efficacy Outcomes and Renal Function in Kidney Transplant Recipients Following Early Switch from Calcineurin Inhibitor to Everolimus: Subanalysis from the ELEVATE Study.
ELEVATE study group, Llobregat Catalunya, Spain.
Background: Human leukocyte antigen (HLA) compatibility between donor and recipient is considered an important factor for graft outcomes. Compatibility is associated with a lower incidence…2016 American Transplant Congress
Zero and One Mismathing for HLA DR10,14,16 Produces Increased Kidney Graft Survival.
Aims: HLA DR matching has shown measureable significant effects in kidney graft survival. Part and parcel of this association is the HLA Class II allele…2016 American Transplant Congress
Factors Associated with Acute Rejections in Kidney Transplant Recipients: Time for HLA-DR Matching in Elderly Recipients?
Nephrology, Charite Universitaetsmedizin, Berlin, Germany.
Background. Within the Eurotransplant Senior Allocation Program (ESP) HLA-matching is neglected,potentially causing inferior outcomes. There is a lack of data analysing the long-term immunologic outcomes…