2022 American Transplant Congress
HLA Alleles Add to Risk Stratification for CMV Infection in Renal Transplant Recipients
*Purpose: Cytomegalovirus (CMV) is the most common viral infection that occurs after solid organ transplantation. The incidence of CMV infection or disease (I/d) varies based…2022 American Transplant Congress
HLA-DRB1 and DQB1 Amino Acid Mismatches as Determinants of Kidney Allograft Failure
*Purpose: It was previously reported that HLA-DRB1 amino acid (AA) mismatches (MMs) at peptide-binding pockets of this molecule account for significant incremental risk of kidney…2022 American Transplant Congress
Improving Value Delivery in Compatible Living Donor Kidney (CLD) Transplant Through Zero-Low Eplet Mismatch via National Kidney Registry (NKR)
1Intermountain Medical Center, Murray, UT, 2CareDX, South San Francisco, CA
*Purpose: Despite advances in diagnostics and therapeutics, kidney allograft survival rates have not increased considerably. Kidney For Life (KFL) through NKR aims to increase access…2021 American Transplant Congress
Effect of HLA-DR Mismatches on Graft Outcomes of Kidney Transplant from Elderly Donors
David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: Human leukocyte antigen (HLA)-DR has been shown to be more immunogenic than HLA-A or -B. The impact of HLA-DR mismatches remains unclear among kidney…2019 American Transplant Congress
DR53, You Can’t See Me: A Deceased Donor Tale of Ambiguous Typing
1VRL Eurofins, Centennial, CO, 2VRL Eurofins, Philadelphia, PA
*Purpose: Our laboratory performs STAT HLA typing for an OPO using RT-PCR methodology. A 46 year old, male Caucasian deceased donor was worked up by…2019 American Transplant Congress
Influence Of HLA-DR Mismatches On Long Term Outcomes Following Heart Transplantation
Division of Cardiology/ JC Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX
*Purpose: In the field of kidney transplantation, there is strong support for the beneficial effect of minimizing donor-recipient HLA incompatibility, and HLA-DR matching in particular…2019 American Transplant Congress
Kidney Transplantation in Older Recipients with HLA-DR Mismatch: Impact of Induction Type on Outcomes
*Purpose: In kidney transplantation, donor-recipient HLA-DR mismatch signals high immunologic risk and can result in poor transplant outcomes. Older kidney transplant recipients (KTRs) are more…2019 American Transplant Congress
HLA-DR Upregulation in Pediatric Kidney Transplant Biopsies
Medical University of South Carolina, Charleston, SC
*Purpose: Renal tubular epithelial cells do not typically express human leukocyte antigen DR (HLA-DR). It’s expression has been associated with different types of tubular injury…2018 American Transplant Congress
HLA-DR4 Matching and Hepatocellular Carcinoma Recurrence after Liver Transplantation
PURPOSE: The phenomenon of graft versus host disease after orthotopic liver transplantation (OLT) is estimated at approximately 1-2%, suggesting that under some circumstances, the graft…2018 American Transplant Congress
Impact of Steroid Maintenance on the Outcomes of HLA-DR Mismatch Kidney Transplantation
Allegheny General Hospital, Pittsburgh, PA.
In kidney transplantation, donor-recipient HLA-DR mismatch poses high immunologic risk and is associated with inferior outcomes. We aimed to explore the impact of enhanced immunosuppression…
American Transplant Congress abstracts