2020 American Transplant Congress
HLA Cw12 in Kidney Transplant Recipients is a Novel Risk Factor for the Development of Post-Transplantation Diabetes: A Single-Centre Retrospective Study
*Purpose: Counselling kidney transplant candidates for their personalised risk of developing post-transplantation diabetes mellitus (PTDM) requires an understanding of risk factors. While some risk factors…2020 American Transplant Congress
The Clinical Significance of C1q+ Antibodies in Pediatric Kidney Transplant Recipients
1Montefiore Medical Center, Bronx, NY, 2Westchester Medical Center, Valhalla, NY
*Purpose: To evaluate the impact of denovo DSA (C1q+ vs C1q-) on graft outcomes in pediatric kidney transplant recipients.*Methods: Children transplanted between 2009 and 2016…2020 American Transplant Congress
Identification of the dnDSA Inducing HLA Mismatches Across Multiple Renal Transplant Centers: A 3-Year Longitudinal Analysis of >11,000 HLA Mismatches in 2271 Patients
*Purpose: The presence of a mismatch (MM) between donor and recipient HLA does not always lead to the patient developing a de novo donor-specific anti-HLA…2020 American Transplant Congress
The Impact of a Positive Crossmatch on KAS Patients and Organs
1Medical Affairs, Hansa Biopharma, Camas, WA, 2Hansa Biopharma, Lund, Sweden, 3UNOS, Richmond, VA
*Purpose: Evaluate the potential effects of offer refusals due to positive crossmatch (+XM) on both patients and re-allocated organs with a focus on waitlist outcomes,…2020 American Transplant Congress
Role of APC Subsets in Rejection and Graft-Versus-Host-Disease in Intestinal Transplantation
Transplant Institute, MedStar Georgetown University, Washington, DC
*Purpose: Intestinal transplantation (ITx) is arguably the most immunogenic and complex organ transplantation, often accompanied with high rates of allograft rejection (AR) and graft-versus-host disease…2020 American Transplant Congress
Donor-Recipient Genetic Relationship and Outcomes of Living Donor Liver Transplantation (LDLT): Does it Really Matter?
1Henry Ford Hospital, Detroit, MI, 2University of Chicago Medical Center, Chicago, IL
*Purpose: The impact of donor-recipient genetic relationship on LDLT outcomes has been raised by some recent reports. We sought to study this over a large…2020 American Transplant Congress
Outcome of Induction Therapies in Low Sensitized Renal Transplant Recipients with Two HLA DR Mismatch in Tacrolimus Era
*Purpose: A mismatch for two HLA DR antigens portends high immunological risk in renal transplant recipients (RTRs). Induction therapies with both rabbit Anti-thymocyte Globulin (r-ATG)…2020 American Transplant Congress
Impact of Catch-Up Vaccinations on Anti-HLA Antibody Responses in Pediatric Kidney Transplant Candidates
*Purpose: Evaluate antibody (Ab) response after catch-up vaccinations in pediatric kidney transplant candidates (PKTC).*Methods: A single center retrospective review of PKTC less than or equal…2020 American Transplant Congress
A Multicenter Analysis of the Proportion and Pattern of Unexplained HLA Antibodies in Kidney Recipients without a History of Sensitization
*Purpose: Previous studies report a high prevalence of unexplained antibody reactivities on the single antigen bead (SAB) test. In a contemporary multicenter cohort of non-sensitized…2020 American Transplant Congress
A New Diagnostic Approach to HLA Testing in Kidney Transplant Patients Using Renal Epithelial Cells
*Purpose: In this study we present a new diagnostic approach to HLA typing in kidney transplant recipients using cultured renal tubular cells from urine samples…
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