Articles tagged "HIV virus"

2019 American Transplant Congress
Barriers to Kidney Transplant Wait Listing among HIV Positive Patients with Advanced Kidney Disease
S. M. Boyle¹, K. Fehr¹, C. Deering², A. Raza¹, M. Harhay¹, G. Malat³, K. Ranganna¹, D. Lee¹
¹Drexel University, Philadelphia, PA, ²University of Toledo, Toledo, OH, ³Hahnemann University Hospital, Philadelphia, PA
*Purpose: Compared to HIV-negative kidney transplant (KT) candidates, the median time to waiting list activation is longer among HIV-positive candidates. Little is known about potential…
2019 American Transplant Congress
The Spread of HIV Donation throughout a DSA
A. Friedman, E. Marquez, J. A. Lewis, K. Delli Carpini
LiveOnNY, New York, NY
*Purpose: Before passage of the HOPE act in late 2013, HIV infection was an absolute contraindication to organ donation. Retrospective review of the records of…
2019 American Transplant Congress
Impact of Everolimus Therapy on HIV Persistence and Gene Expression in Transplant Patients
A. Zarinsefat¹, C. Schreiner¹, C. Cameron², S. Chu¹, M. P. Busch¹, T. Liegler¹, S. G. Deeks¹, T. J. Henrich¹, P. G. Stock¹
¹UC San Francisco, San Francisco, CA, ²Case Western Reserve University, Cleveland, OH
*Purpose: mTOR is a key regulatory kinase that controls cell-cycle progression. mTOR inhibitors have been shown to reduce expression of CCR5 and promote viral transcriptional…
2019 American Transplant Congress
The National Landscape of Heart Transplant Candidates with HIV
A. A. Shaffer¹, A. G. Thomas², D. L. Segev¹
¹Surgery & Epidemiology, Johns Hopkins University, Baltimore, MD, ²Epidemiology, University of North Carolina, Chapel Hill, NC
*Purpose: Heart disease is a leading cause of death for HIV+ individuals, and the number of HIV+ heart transplant (HT) recipients is growing. Although understanding…
2019 American Transplant Congress
National Landscape of Donors Allocated through the Hope Act in the United States
A. R. Wilk¹, R. Hunter², M. A. McBride², D. K. Klassen²
¹Research, United Network for Organ Sharing, Richmond, VA, ²United Network for Organ Sharing, Richmond, VA
*Purpose: To address the shortage of donor organs and to increase transplantation opportunities for HIV+ recipients, the HIV Organ Policy Equity (HOPE) Act was enacted…
2019 American Transplant Congress
HOPE in Action: A Multicenter Prospective Study of HIV to HIV Liver Transplantation
C. Durand¹, S. Florman², M. Bowring³, D. Brown¹, B. Haydel², J. Hamilton¹, P. Stock⁴, J. Price⁵, T. Pruett⁶, V. Kirchner⁷, D. Wojciechowksi⁸, N. Turgeon⁹, C. Wolfe¹⁰, V. Stosor¹¹, J. Charette¹¹, A. Cameron³, S. Ottmann³, S. Huprikar¹², D. Segev³
¹Medicine, Johns Hopkins University, Baltimore, MD, ²Surgery, Mount Sinai, New York, NY, ³Surgery, Johns Hopkins University, Baltimore, MD, ⁴Surgery, University of California San Francisco, San Francisco, CA, ⁵Medicine, University of California San Francisco, San Francisco, CA, ⁶Surgery, University of Minnesota, Minneapolis, MN, ⁷Medicine, University of Minnesota, Minneapolis, MN, ⁸Medicine, Mass General Hospital, Boston, MA, ⁹Surgery, Emory University, Atlanta, GA, ¹⁰Medicine, Duke University, Durham, NC, ¹¹Medicine, Northwestern University, Chicago, IL, ¹²Medicine, Mount Sinai, New York, NY
*Purpose: HIV+ liver transplant (LT) candidates face higher mortality and lower access to transplant compared to HIV- counterparts. With the US HOPE Act, HIV+ donor…
2019 American Transplant Congress
Access To The Kidney Transplant Waitlist For Patients With Hiv And End-stage Renal Disease
A. A. Shaffer¹, H. Ying², N. Chu¹, A. G. Thomas³, C. Haugen², S. Norman⁴, D. L. Segev¹, M. A. McAdams-DeMarco¹
¹Surgery & Epidemiology, Johns Hopkins University, Baltimore, MD, ²Surgery, Johns Hopkins University, Baltimore, MD, ³Epidemiology, University of North Carolina, Chapel Hill, NC, ⁴Surgery, University of Michigan, Ann Arbor, MI
*Purpose: Patients with HIV and end-stage renal disease (ESRD) experience higher mortality on dialysis than those without HIV. These HIV+ dialysis patients may face barriers…
2019 American Transplant Congress
Opening the Doors of Hope: HIV-Positive Living Kidney Donation
S. Rusch, L. Fieldman, M. Hemmersbach-Miller, C. R. Wolfe
Duke University Medical Center, Durham, NC
*Purpose: Living donation (LD) has been allowed under the HOPE Act since 2013, yet to date there have been no HIV+ LD organ transplants performed…
2019 American Transplant Congress
Optimal Timing of Hepatitis C Treatment among HIV/HCV Co-Infected End-Stage Renal Disease Patients: Pre vs. Post-Transplant
B. Shelton¹, G. Berdahl¹, D. Sawinski², B. Linas³, P. Reese², M. Mustian¹, R. Reed¹, P. MacLennan¹, J. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, ³Boston University School of Medicine, Boston, MA
*Purpose: End-stage renal disease (ESRD) patients co-infected with HCV and HIV have access to effective treatment options for HCV infection. However, they also have access…
2019 American Transplant Congress
HIV Resistance among HOPE Donor Referrals
B. Barnaba¹, W. Werbel¹, O. Kusemiju¹, C. Kirby¹, Y. Eby¹, R. Fernandez¹, J. Miller¹, A. Redd², D. Segev¹, A. Tobian¹, C. Durand¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²National Institute of Allergy and Infectious Diseases, Bethesda, MD
*Purpose: After success in South Africa, HIV+ deceased donor (HIV D+) organs can now be used for transplant to HIV+ recipients in the US under…