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Articles tagged "HIV virus"

  • 2022 American Transplant Congress

    Lung Transplantation Outcomes in Recipients Living with HIV in the United States

    J. M. Czeresnia1, S. Madan2, M. M. Abbasi3, V. Hemmige1

    1Department of Medicine - Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY, 2Department of Medicine - Division of Cardiology, Montefiore Medical Center, Bronx, NY, 3Department of Surgery - Division of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY

    *Purpose: To compare outcomes of lung transplantation in HIV-positive and HIV-negative recipients in the United States.*Methods: A national transplant database (UNOS/SRTR) was queried for cases…
  • 2022 American Transplant Congress

    Upregulation of Innate Immune Pathways is Associated with Increased Rejection in HIV-Infected Kidney Transplant Recipients

    A. Zarinsefat1, Y. Kelly1, D. Dobi1, G. Szabo1, Z. Laszik1, P. Stock1, H. Braun2

    1UC San Francisco, San Francisco, CA, 2CA

    *Purpose: Although kidney transplantation (KT) has become the standard of care for HIV+ patients with renal failure, early experiences revealed high acute rejection (AR) rates.…
  • 2022 American Transplant Congress

    Temporal Trends of Optn Hope Act Variance Participation

    A. Wilk1, M. Green2, C. Marsh3, N. Theodoropoulos4, R. Formica5, N. Turgeon6, A. Fox7, A. Wilhelm1, D. Klassen1

    1UNOS, Richmond, VA, 2UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 3Scripps Clinic & Scripps Green Hospital, La Jolla, CA, 4UMass Medical, Worcester, MA, 5Yale, New Haven, CT, 6UT Health Austin, Austin, TX, 7CUIMC/Presbyterian Hospital, New York, NY

    *Purpose: The Organ Procurement and Transplantation Network (OPTN) created a research variance allowing for transplantation of HIV+ donor kidneys and livers into HIV+ recipients after…
  • 2022 American Transplant Congress

    Outcomes of Primary Kidney Transplant Recipients with Human Immunodeficiency Virus According to Induction Immunosuppression in the United States

    K. Bhunia1, K. Swanson1, A. Bregman1, R. El-Rifai1, R. Spong1, S. Jackson2, S. Riad3

    1MEDICINE, University of Minnesota, Minneapolis, MN, 2Analytics, MHealth-Fairview, Minneapolis, MN, 3Medicine, University of Minnesota, Minneapolis, MN

    *Purpose: Early reports of outcomes in recipients with HIV suggested lower kidney rejection rate in association with depletional induction. However, these reports did not assess…
  • 2022 American Transplant Congress

    Compliance with OPTN Infectious Disease Testing

    L. Irwin

    Massachusetts General Hospital, Boston, MA

    *Purpose: Effective 3/1/21 OPTN policy requires all transplant recipients to have pre-transplant and post-transplant infectious disease testing performed at specific intervals: upon admission and prior…
  • 2022 American Transplant Congress

    Consent to Organ Offers from Public Health Service Increased Risk Donors Decreases Time to Transplant and Waitlist Mortality

    Y. Kelly, A. Zarinsefat, M. Tavakol, A. Shui, C. Huang, J. P. Roberts

    University of California, San Francisco, San Francisco, CA

    *Purpose: The Public Health Service Increased Risk designation identified organ donors at increased risk of transmitting hepatitis B, hepatitis C, and human immunodeficiency virus. Despite…
  • 2022 American Transplant Congress

    Antibody Responses to an Additional Dose of SARS-CoV-2 mRNA Vaccine in Solid Organ Transplant Recipients with and without HIV

    M. Saksena1, G. Carrara2, B. Haydel2, A. Azad1, K. Srivastava1, C. Gleason1, K. Beach1, L. Sominsky1, A. Oostenink1, G. Cai1, J. Carreno Quiroz1, G. Singh1, S. Florman2, C. Cordon-Cardo3, J. Aberg4, A. Wajnberg5, F. Krammer1, V. Simon1, M. Rana4

    1Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 2Recanati/Miller Transplantation Institute, Mount Sinai Hospital, New York, NY, 3Pathology, Molecular and Cell based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 4Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 5General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: Solid organ transplant (SOT) recipients mount suboptimal immune responses to a two-dose SARS-CoV-2 mRNA vaccine series. Data regarding antibody responses in HIV and SOT…
  • 2022 American Transplant Congress

    Seroprevalence of HHV8 Among Donors and Recipients with HIV

    P. H. Nambiar1, T. Liang2, J. D. Motter3, W. Werbel3, S. Mehta4, V. Kirchner5, M. Rana6, S. Florman7, J. Odim8, W. Miley9, N. Labo9, D. Whitby9, A. Massie10, D. Segev3, A. Tobian3, C. Durand2

    1Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 2Medicine, Johns Hopkins University, Baltimore, MD, 3Johns Hopkins University, Baltimore, MD, 4New York University Langone Transplant Institute, New York, NY, 5University of Minnesota, Minneapolis, MN, 6Icahn School of Medicine at Mount Sinai, New York, NY, 7Mount Sinai Medical Center, New York, NY, 8National Institute of Health, Bethesda, MD, 9National Cancer Institute, Frederick, MD, 10Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Kaposi sarcoma (KS) can develop post-transplant via recipient HHV8 reactivation or donor-acquired HHV8. In the general US population, HHV8 seroprevalence is low (1-5%), yet…
  • 2022 American Transplant Congress

    Case-Control Study of Belatacept as Maintenance Immunosuppression in Kidney Transplant Recipients Living with HIV

    M. Tucker, C. Foppiano Palacios, E. Cohen, S. Virmani, P. Trubin, L. A-Barakat, M. M. Azar, M. Malinis

    Yale School of Medicine, New Haven, CT

    *Purpose: Belatacept has been increasingly used in kidney transplant recipients (KTR) as a calcineurin-inhibitor (CNI) sparing agent. There are little data on belatacept use in…
  • 2022 American Transplant Congress

    Recipient and Kidney Graft Outcomes of Human Immunodeficiency Virus Positive Deceased Donors in the United States

    K. J. Swanson1, R. El-Rifai1, A. Bregman1, R. Spong1, V. Kirchner2, T. Pruett2, S. Jackson3, S. M. Riad1

    1Division of Nephrology & Hypertension, University of Minnesota, Minneapolis, MN, 2Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN, 3M-Health Fairview Analytics, Minneapolis, MN

    *Purpose: With the inception of the HIV Organ Policy Act, HIV-positive donor to HIV-positive recipient kidney transplantation is a novel form of transplantation in the…
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