ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "High-risk"

  • 2022 American Transplant Congress

    Evaluation of Prophylactic Valganciclovir Dosing in Kidney Transplant Recipients at an Urban Transplant Institution

    E. Foster1, D. Pierce1, T. Cairns1, S. Borgetti2, I. Tzvetanov3, E. Benedetti3, C. Muran1

    1Pharmacy, University of Illinois at Chicago, Chicago, IL, 2Medicine, University of Illinois at Chicago, Chicago, IL, 3Surgery, University of Illinois at Chicago, Chicago, IL

    *Purpose: Dosing and duration of cytomegalovirus (CMV) prophylaxis with valganciclovir (VGC) in kidney transplant (KT) recipients is variable by transplant center. Prior studies have shown…
  • 2022 American Transplant Congress

    Preemptive  Therapy for Cytomegalovirus (CMV) Disease Prevention in High-Risk CMV Donor Seropositive Recipient Seronegative (D+/R-) Liver Transplant Recipients in a Real-World Setting 

    K. M. Doss1, C. Kling1, M. R. Heldman1, N. Singh2, M. Wagener3, C. E. Fisher1, A. Limaye1

    1University of Washington, Seattle, WA, 2University of Pittsburgh, PIttsburgh, PA, 3University of Pittsburgh, Pittsburgh, PA

    *Purpose:  Preemptive therapy  (PET)  has  demonstrated superiority to antiviral prophylaxis  for  prevention of  cytomegalovirus (CMV)  disease  in  CMV  donor seropositive/recipient seronegative (D+R-)  liver transplant recipients …
  • 2022 American Transplant Congress

    Donor Kidneys from Communities with Higher Deprivation Are Significantly More Likely to be Discarded

    J. Schold1, A. Huml1, E. Poggio1, E. Dewey1, R. Buchalter1, S. Husain2, S. Mohan2

    1Cleveland Clinic, Cleveland, OH, 2Columbia University, New York, NY

    *Purpose: The proportion of kidneys procured for the purpose of transplantation but ultimately discarded exceeds 20% in the US. Factors associated with deceased donor kidney…
  • 2021 American Transplant Congress

    T-cell-Mediated Immunity to Sars-cov-2 Defines Covid-19 Risk and Severity in Transplanted and Non-Transplanted Individuals and Associates with Myeloid-Derived Suppressor Cells

    C. Ashokkumar1, V. Rohan2, A. H. Kroemer3, S. Rao4, G. Mazariegos5, B. W. Higgs5, S. Nadig2, M. Ningappa5, T. Fishbein3, S. Subramaniam6, R. Sindhi7

    1Plexision, Pittsburgh, PA, 2Medical University of South Carolina, Charleston, SC, 3MedStar Georgetown Transplant Institute, Georgetown, DC, 4DHR Health Institute for Research and Development, Texas, TX, 5University of Pittsburgh, Pittsburgh, PA, 6University of California, San Diego, CA, 7University of Pittsburgh, pittsburgh, PA

    *Purpose: We assessed whether COVID-19-risk is enhanced by chronic immunosuppression, and is associated with suppressor cells.*Methods: We tested 66 COVID-19 patients, including 26 with solid…
  • 2021 American Transplant Congress

    Outcomes of Cytomegalovirus Status Determining Induction Therapy in Lung Transplant

    K. Heagler1, J. Lyons1, B. Bemiss2, P. Stracener1

    1Pharmacy, Loyola University Medical Center, Maywood, IL, 2Loyola University Medical Center, Maywood, IL

    *Purpose: At the study institution, basiliximab induction is withheld in lung transplant recipients who are cytomegalovirus (CMV) high risk due to concern for increased CMV…
  • 2021 American Transplant Congress

    Overall Survival by Best Overall Response with Tabelecleucel in Patients with Epstein-Barr Virus-Driven Post-Transplant Lymphoproliferative Disease After Solid Organ Transplant

    S. Prockop1, L. Gamelin2, R. Dinavahi2, Y. Sun2, N. Guzman-Becerra2, H. Parmar2

    1Memorial Sloan Kettering Cancer Center, New York, NY, 2Atara Biotherapeutics, South San Francisco, CA

    *Purpose: Tabelecleucel is an investigational, off-the-shelf, allogeneic Epstein-Barr virus (EBV)-specific T-cell immunotherapy being studied in patients (pts) with serious EBV-driven diseases, including post-transplant lymphoproliferative disease…
  • 2021 American Transplant Congress

    Not Always as it Seems: Lack of Hepatitis C Virus Transmission from Nucleic Acid Testing Positive Deceased Donors

    A. Nishio Lucar1, A. Kumar1, S. Rao1, V. L. Kelly1, K. Coles2, J. Kamal1, C. W. Green1, A. M. Doyle1

    1Medicine, University of Virginia, Charlottesville, VA, 2University of Virginia, Charlottesville, VA

    *Purpose: Hepatitis C virus (HCV) + organs are increasingly use to transplant HCV naive candidates with good short-term outcomes. HCV transmission with HCV nucleic acid…
  • 2021 American Transplant Congress

    Trends and Outcomes Analysis of U.S. Transplant Centers Performing High Volumes of Hard to Place Kidneys

    D. Bahl1, A. Mahajan2, H. Aramada3, Y. Qazi3

    1St. George's University, St. George's, Grenada, 2University College Cork School of Medicine, County Cork, Cork City, Ireland, 3Keck Hospital of USC, Los Angeles, CA

    *Purpose: Despite a growing number of patients awaiting a kidney transplant, discard rate remains significantly high. The UNOS SRTR data now provides information on all…
  • 2021 American Transplant Congress

    Efficacy of Hope: Analysis of Quality HIV+ Deceased Donor Organ Availability

    G. E. Owens1, B. Shelton1, P. MacLennan1, D. Sawinski2, J. E. Locke1

    1Transplant, University of Alabama at Birmingham, Birmingham, AL, 2Transplant, University of Pennsylvania, Philadeplphia, PA

    *Purpose: The purpose of this study is to understand the number of organs actually available for HIV+ to HIV+ transplant utilizing data on a national…
  • 2021 American Transplant Congress

    Alemtuzumab vs Antithymocyte Globulin Induction in Hepatitis C Viremic Donors to Hepatis C Negative Kidney Transplant Recipients

    K. Walter, L. Mincemoyer, J. Giang, J. Suero, N. Shah, K. Szempruch

    University of North Carolina Medical Center, Chapel Hill, NC

    *Purpose: The optimal induction agent for kidney transplantation of hepatitis C virus nucleic acid test positive donors to negative recipients (HCV NAT D+/R-) is unknown.…
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