Articles tagged "Hepatocellular carcinoma"

2016 American Transplant Congress
Selection of Patients with Solitary Lesion of Hepatocellular Cancer for Liver Transplantation.
M. Grąt,¹ J. Stypułkowski,¹ W. Patkowski,¹ K. Wronka,¹ M. Wasilewicz,² K. Grąt,³ L. Masior,¹ M. Krasnodębski,¹ Z. Lewandowski,⁴ M. Krawczyk.¹
¹Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland; ²Department of General, Transplant and Liver Surgery, Liver and Internal Medicine Unit, Medical University of Warsaw, Warsaw, Poland; ³Second Department of Clinical Radiology, Medical University of Warsaw, Warsaw, Poland; ⁴Department of Epidemiology, Medical University of Warsaw, Warsaw, Poland.
Milan criteria are considered as benchmark for selection of patients with hepatocellular cancer (HCC) for liver transplantation. The aim of this study was to evaluate…
2016 American Transplant Congress
Visceral Adiposity Is Associated with Increased Recurrence of Hepatocellular Carcinoma Following Liver Transplantation.
A. Mathur, L. Boyangzi, M. Prince, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, T. Kato, J. Emond.
Abdominal Transplant, Columbia University, Ny, NY.
IntroductionObesity has become a worldwide epidemic. The number of patients with HCC undergoing Orthotopic liver transplant (OLT) is rising. Epidemiologic evidence suggests a link between…
2016 American Transplant Congress
Which Is the Predictable Value of Post-Transplant HCC Recurrence Between Tumor-Related Factors at the Initial Diagnosis and the Transplantation?
J. Lee,^1,2 J. Lee,¹ J. Lee,³ S. Song,¹ J. Lee,¹ S.-K. Kwon,¹ M. Ju,^1,2 M. Kim,^1,2 G. Choi,^1,2 J. Choi,^1,2 S. Kim,^1,2 D. Joo.^1,2
¹Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; ²Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; ³Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea.
Background: Milan criteria is best options to decide whether patients with HCC underwent liver transplantation. However, Milan Criteria is not including values at time of…
2016 American Transplant Congress
Metabolomic Profiles of Hepatocellular Carcinoma and Cirrhotic Patients Before and After Transplantation.
C. Desai,¹ R. Varghese,² S. Robertazzi,¹ C. Di Poto,² A. Ferrarini,² C. Tu,² R. Girlanda,¹ K. Khan,¹ T. Fishbein,¹ H. Ressom.²
¹Medstar Georgetown Transplant institute, Washington DC; ²Department of Oncology, Lombardi Comprehensive Cancer Center, Washington DC.
Metabolomics offers the opportunity to characterize complex diseases like hepatocellular carcinoma (HCC) through a systematic evaluation of thousands of metabolites in human liver tissues and…
2016 American Transplant Congress
Dysfunctional Production of Adipocytokines in Obesity Results in Inferior Oncologic Outcomes from Hepatocellular Carcinoma Following Liver Transplantation.
A. Mathur, E. Presbyskowski, D. Carpenter, E. Zorn, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, Y. Veras, K. Tomoaki, J. Emond.
Abdominal Transplant, Columbia University, Ny, NY.
IntroductionOver 2 billion people worldwide are obese. There is strong evidence of an association between obesity and hepatocellular (HCC) cancer.This effect is mediated through an…
2016 American Transplant Congress
Which Is the Predictable Values of Post-Transplant Hepatocellular Carcinoma Recurrence in Patients Received Down Staging Therapy or Bridging Therapy?
S. Song, J. Lee, S.-K. Kwon, J. Lee, J. Lee, D. Han, G. Choi, M. Kim, J. Choi, S. Kim, D. Joo.
Department of Surgery and The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea.
Introduction: Liver transplantation (LT) is one of the best treatment for small hepatocellular carcinoma (HCC) in patients with liver cirrhosis. However, many patients do not…
2016 American Transplant Congress
CoCl2 Induced ER Stress Protein Mediated Cytotoxicity in FK506 Treated Hepatoma HepG2 Cells.
S. Choi, S. Chung.
Surgery, Chonnam National University Hospital, Gwangju, Republic of Korea; Surgery, Chonnam National University Hospital, Gwangju, Republic of Korea.
Background; The effects of FK506 on the endoplasmic reticulum (ER) mediated stress pathway accelerates CoCl2 - induced cytotoxicity in human hepatoma HepG2 cell line were…
2016 American Transplant Congress
Pre-Transplant Intra-Arterial Liver Directed Therapy Does Not Increase the Risk of Hepatic Arterial Misadventures in Liver Transplantation.
J. Kallini,² A. Gabr,² R. Salem,² R. Lewandowski,² T. Baker.¹
¹Comprehensive Transplant Center, Northwestern University, Chicago, IL; ²Division of Interventional Oncology, Northwestern University, Chicago, IL.
Background: Pretransplant liver directed therapy has emerged as standard of care for patients with end stage liver disease complicated by unresectable hepatocellular cancer. The aim…
2015 American Transplant Congress
Risk of Post Liver Transplant (LT) Hepatocellular Carcinoma (HCC) Recurrence Is 2-Fold Higher in Women Compared to Men With AFP Levels at LT Between 101-500
M. Sarkar,¹ J. Dodge,² F. Yao,¹ J. Roberts,² N. Terrault,¹ N. Mehta.¹
¹Medicine, University of California, San Francisco, San Francisco; ²Surgery, University of California, San Francisco, San Francisco.
Gender differences in HCC incidence are known, with men at greater risk than women. Pre transplant AFP levels strongly predict post LT HCC recurrence, though…
2015 American Transplant Congress
Alpha-Fetoprotein as a Modifier of Anatomic Criteria for Transplantation of HCC Patients
A. Daoud,^1,3 M. Ghobrial,¹ L. Teeter,² E. Graviss,² E. Asham,¹ S. Burroughs,¹ A. Saharia,¹ C. Mobley,¹ S. Mogawer,³ A. Sholkamy,³ M. Elshazly,⁴ M. Boktour,¹ A. Gaber.¹
¹Transplant Center, Methodist Hospital, Houston, TX; ²Pathology and Genomic Medicine, Methodist Hospital, Houston, TX; ³Internal Medicine Department, Cairo University Medical school, Cairo, Egypt; ⁴Surgery Department, Cairo University Medical school, Cairo, Egypt.
Background:The current listing criteria (Milan, UCSF) for Orthotropic Liver Transplants (OLT) in hepatocellular carcinoma (HCC) patients emphasize the anatomic features of the tumor such as…