Articles tagged "Hepatocellular carcinoma"

2016 American Transplant Congress
Is Pretransplant Determination of Hepatocellular Carcinoma Tumor Grade Using Needle Biopsy Reliable for Transplant Candidate Selection? Analysis of 217 Liver Transplant Recipients.
C. Court, M. Harlander-Locke, D. Markovic, F. Kaldas, A. Zarrinpar, D. Farmer, S. Sho, J. Tomlinson, J. Hiatt, R. Busuttil, V. Agopian, D. Lu, S. Raman.
Department of Surgery, UCLA, Los Angeles, CA.
Objective: Despite the prognostic significance of tumor grade and vascular invasion for patients with hepatocellular carcinoma (HCC), preoperative needle biopsy (PNB) is not routinely utilized…
2016 American Transplant Congress
Predictive Value of Preoperation Serum Gamma-Glutamyltranspeptidase for Hepatocellular Carcinoma Prognosis After Liver Transplantation.
S. Fu, Q. Zhao, M. Chen, L. Wu, Q. Ren, F. Ji, Z. Guo, X. He.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Objectives: The aims of this study were to evaluate the prognostic value of preoperative serum gamma-glutamyltranspeptidase (γ-GGT) in patients with hepatocellular carcinoma (HCC) underwent liver…
2016 American Transplant Congress
The Influence of Rising Lab MELD on Vascular Invasion in HCC.
K. Halazun, E. Przybyszewski, E. Verna, B. Samstein, A. Fox, R. Brown, J. Emond.
Liver Transplant & HPB Surgery, Weill Cornell Medical College, NY, NY.
Background Vascular invasion (VI) is one of the most important predictors of HCC recurrence. Although attempts to identify predictors of VI have been made, datasets…
2016 American Transplant Congress
Selection of Patients with Solitary Lesion of Hepatocellular Cancer for Liver Transplantation.
M. Grąt,¹ J. Stypułkowski,¹ W. Patkowski,¹ K. Wronka,¹ M. Wasilewicz,² K. Grąt,³ L. Masior,¹ M. Krasnodębski,¹ Z. Lewandowski,⁴ M. Krawczyk.¹
¹Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland; ²Department of General, Transplant and Liver Surgery, Liver and Internal Medicine Unit, Medical University of Warsaw, Warsaw, Poland; ³Second Department of Clinical Radiology, Medical University of Warsaw, Warsaw, Poland; ⁴Department of Epidemiology, Medical University of Warsaw, Warsaw, Poland.
Milan criteria are considered as benchmark for selection of patients with hepatocellular cancer (HCC) for liver transplantation. The aim of this study was to evaluate…
2016 American Transplant Congress
Visceral Adiposity Is Associated with Increased Recurrence of Hepatocellular Carcinoma Following Liver Transplantation.
A. Mathur, L. Boyangzi, M. Prince, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, T. Kato, J. Emond.
Abdominal Transplant, Columbia University, Ny, NY.
IntroductionObesity has become a worldwide epidemic. The number of patients with HCC undergoing Orthotopic liver transplant (OLT) is rising. Epidemiologic evidence suggests a link between…
2016 American Transplant Congress
Which Is the Predictable Value of Post-Transplant HCC Recurrence Between Tumor-Related Factors at the Initial Diagnosis and the Transplantation?
J. Lee,^1,2 J. Lee,¹ J. Lee,³ S. Song,¹ J. Lee,¹ S.-K. Kwon,¹ M. Ju,^1,2 M. Kim,^1,2 G. Choi,^1,2 J. Choi,^1,2 S. Kim,^1,2 D. Joo.^1,2
¹Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; ²Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; ³Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea.
Background: Milan criteria is best options to decide whether patients with HCC underwent liver transplantation. However, Milan Criteria is not including values at time of…
2016 American Transplant Congress
Metabolomic Profiles of Hepatocellular Carcinoma and Cirrhotic Patients Before and After Transplantation.
C. Desai,¹ R. Varghese,² S. Robertazzi,¹ C. Di Poto,² A. Ferrarini,² C. Tu,² R. Girlanda,¹ K. Khan,¹ T. Fishbein,¹ H. Ressom.²
¹Medstar Georgetown Transplant institute, Washington DC; ²Department of Oncology, Lombardi Comprehensive Cancer Center, Washington DC.
Metabolomics offers the opportunity to characterize complex diseases like hepatocellular carcinoma (HCC) through a systematic evaluation of thousands of metabolites in human liver tissues and…
2016 American Transplant Congress
Dysfunctional Production of Adipocytokines in Obesity Results in Inferior Oncologic Outcomes from Hepatocellular Carcinoma Following Liver Transplantation.
A. Mathur, E. Presbyskowski, D. Carpenter, E. Zorn, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, Y. Veras, K. Tomoaki, J. Emond.
Abdominal Transplant, Columbia University, Ny, NY.
IntroductionOver 2 billion people worldwide are obese. There is strong evidence of an association between obesity and hepatocellular (HCC) cancer.This effect is mediated through an…
2015 American Transplant Congress
Early Detection of HCC Mutations in Indeterminate Lesions Using Liquid Biopsies
Y. Lin,¹ K. Cavaness,² Z. Zhang,¹ S. Lin,³ K. Korenblat,¹ G. Klintmalm,² W. Chapman.¹
¹Washington University, St. Louis, MO; ²Baylor University, Dallas, TX; ³Stanford University, Palo Alto, CA.
Background Recent sequencing efforts have characterized the mutation profile of hepatocellular carcinoma (HCC); however, the relevance to clinical decision-making has been limited by the infrequency…
2015 American Transplant Congress
Long-Term Outcome After Liver Transplantation for Unresectable Hepatocellular Carcinoma Following Yttrium-90 Radioembolization Bridging Treatment
S. Radunz,¹ T. Benkoe,¹ J. Best,² A. Bockisch,³ T. Lauenstein,⁴ H. Baba,⁵ A. Paul,¹ J. Treckmann.¹
¹General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; ²Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany; ³Nuclear Medicine, University Hospital Essen, Essen, Germany; ⁴Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany; ⁵Pathology and Neuropathology, University Hospital Essen, Essen, Germany.
Background: Liver transplantation remains the only curative treatment option for patients with unresectable hepatocellular carcinoma (HCC). Several bridging treatments are employed because the limited availability…