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Articles tagged "Hepatocellular carcinoma"

  • 2018 American Transplant Congress

    ABO‐incompatible Deceased Donor Liver Transplantation

    X. Luo, C. Haugen, A. Thomas, J. Garonzik-Wang, D. Segev.

    Johns Hopkins, Baltimore, MD.

    ABO-incompatible liver transplantation (ILT) has increased over the past decade despite reports suggesting that adult ILT recipient have worse outcomes than ABO-compatible liver transplant (CLT)…
  • 2018 American Transplant Congress

    Prognostic Value and Biological Significances of Five Long Non-Coding RNAs in Hepatocellular Carcinoma

    Y. Hou,1 Z. Yu,2 N. Tam,1 S. Huang,1 J. Yang,1 L. Wu,1 Y. Ma,1 X. He.1

    1Department of Organ Transplantation, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China; 2Laboratory of Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.

    Objectives Increasing evidence suggests that long non-coding RNA (lncRNA) plays a vital role in metastasis and development in hepatocellular carcinoma (HCC). Tumor progression severely affect…
  • 2018 American Transplant Congress

    Small-for-Size Grafts Increase Recurrence of Hepatocellular Carcinoma in Liver Transplantation beyond Milan Criteria

    E. Lee, S. Kim, J. Shim, J. Park, B. Na, S-.J. Park.

    Center for Liver Cancer, National Cancer Center, Goyang, Korea.

    BACKGROUND: Living donor liver transplantation (LDLT) has been reported to have high rates of hepatocellular carcinoma (HCC) recurrence compared to deceased donor liver transplant (DDLT).…
  • 2018 American Transplant Congress

    TP53 Mutations Lead to Increased Transcription of Circular RNAs in Exosomes Enhancing Tumor Invasiveness in Hepatocellular Carcinoma Bases on Bioinformatics Analysis

    Z. Yu, Y. Hou, R. Wang, X. Huang.

    The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.

    Objective Increasing evidence suggests that cicular RNAs play an important role in tumor. A recent study found the enrichment of cicular RNAs in HCC derived…
  • 2018 American Transplant Congress

    Impact of Donor Age on Outcomes after Living Donor Liver Transplantation

    K. Hayashi,1 K. Gotoh,1 H. Eguchi,1 Y. Iwagami,1 D. Yamada,1 T. Asaoka,1 T. Noda,1 K. Kawamoto,1 S. Kobayashi,1 K. Umeshita,2 Y. Doki,1 M. Mori.1

    1Dept of Gastroenterological Sugery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan; 2Division of Health Science, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

    Background: Liver transplantation (LT) is a curative treatment for decompensated cirrhosis and fulminant hepatitis. Although not a few patients received LT with marginal donor livers…
  • 2018 American Transplant Congress

    Validating MORAL in Living Donor Liver Transplantation for Hepatocellular Carcinoma

    A. Bhatti, A. Qureshi, N. Khan, M. Butt, A. Waheed, A. Rana, F. Dar.

    Hepatobiliary Surgery and Liver Transplantation, Hepatology, Radiology, Shifa International Hospital, Islamabad, Pakistan.

    The “Model of Recurrence after Liver Transplant” (MORAL) study has identified certain pre and post operative variables that have significant impact on recurrence free survival…
  • 2018 American Transplant Congress

    Living Donor Liver Transplantation for Hepatocellular Carcinoma beyond UCSF Criteria: Can We Achieve a Modest Long-Term Survival? A Single Center Retrospective Analysis of Using Extended Criteria

    A. Thorat, L.-B. Jeng, S.-C. Hsu, C.-C. Yeh, T.-H. Chen, H.-R. Yang, K.-S. Poon, P.-C. Li.

    Organ Transplantation Center, China Medical University Hospital, Taichung, Taiwan.

    Milan's criteria were universally validated for LT in HCC patients and, were accepted as allocation criteria of UNOS in 2001 & Eurotransplantation in 2006. However,…
  • 2018 American Transplant Congress

    Prediction of Hepatocellular Carcinoma Recurrence Following Liver Transplantation Using Combined Differential Gene Expression, Copy Number Variation and Somatic Mutation Analysis

    A. Humar,1 P. Liu,2 J. Luo,3 M. Nalesnik,3 A. Singhi,3 G. Tseng,2 G. Michalopoulos.3

    1Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Biostatistics, University of Pittsburgh, Pittsburgh, PA; 3Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.

    Liver allocation for transplant candidates with hepatocellular carcinoma is limited by OPTN policy to patients whose tumors remain within size limits defined by Milan criteria.…
  • 2017 American Transplant Congress

    Different Prognostic Factors for Early and Late Recurrence After Adult Living Donor Liver Transplantation for Hepatocellular Carcinoma.

    S. Hong, K.-W. Lee, H.-S. Kim, S.-W. Ahn, K. Yoon, H. Kim, N.-J. Yi, K.-S. Suh.

    Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea

    Recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) remains unsatisfactory. However, some patients with HCC recurrence after LT show good long-term survival results. The…
  • 2017 American Transplant Congress

    Effects of the Gut-Liver Axis on Ischemia-Mediated Hepatocellular Carcinoma Recurrence in the Mouse Liver.

    L. Orci,1 S. Lacotte,1 V. Delaune,1 G. Oldani,1 F. Slits,1 C. Rossetti,2 L. Rubbia-Brandt,3 P. Morel,1 C. Toso.1

    1Hepato-pancreato-biliary Centre, Department of Surgery, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland; 2Dipartimento di Biotecnologie e Scienze della Vita, Università degli Studi dell'Insubria, Varese, Italy; 3Division of Clinical Pathology, Department of Pathology and Immunology, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

    Background: There is growing evidence that liver graft ischemia-reperfusion (I/R) is a risk factor for hepatocellular carcinoma (HCC) recurrence after liver transplantation, but the involved…
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