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Articles tagged "Hepatitis C"

  • 2021 American Transplant Congress

    Transplanting Hepatitis C Infected Organs Into Uninfected Recipients: A Pharmacy Perspective

    M. L. Holt, A. James, K. Gutierrez, T. Sparkman, J. Banbury, D. Jones

    University of Alabama at Birmingham Hospital, Birmingham, AL

    *Purpose: Due to direct acting antivirals (DAAs), hepatitis C virus (HCV) positive patients are now resources for organ transplantation in HCV negative recipients. Our institution…
  • 2021 American Transplant Congress

    Use of Donor Blood Expedites HCV Genotyping and Allows Earlier DAA Initiation for Recipients of HCV+ Kidneys

    B. Lonze, N. Ali, R. Montgomery, Z. Stewart Lewis

    Tranplant Institute, NYU Langone Health, New York, NY

    *Purpose: Utilization of HCV viremic donor kidneys for transplant into HCV naïve recipients has become more widespread, yet best practices governing the initiation, timing or…
  • 2021 American Transplant Congress

    Pilot Study for the Use of Shortened Preemptive Therapy with Glecaprevir/pibrentasvir (g/p) and Ezetimibe in Hepatitis C Seronegative Solid Organ Transplant Recipients (Kidney and Heart) of Hepatitis C Viremic Donors

    B. Aqel1, H. Khamash2, A. Moss3, D. E. Steidley4, R. C. Dickson1

    1Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ, 2Nephrology and Hypertension, Mayo Clinic, Phoenix, AZ, 3Transplant Surgery, Mayo Clinic, Phoenix, AZ, 4Cardiology, Mayo Clinic, Phoenix, AZ

    *Purpose: This prospective study aims to assess the efficacy of preemptive therapy with eight days of a combination of direct-acting antivirals (DAAs) (Mavyret) (Pibrentasvir /Glecaprevir)…
  • 2021 American Transplant Congress

    The Use of Hcv Nat+ Organs in Hcv Negative Recipients with On-site Specialty Pharmacy Services: A Win for the Patient, the Transplant Center, and Society?

    M. Person, N. Patel, W. Simerlein, H. Meadows, D. DuBay, D. Taber

    Medical University of South Carolina, Charleston, SC

    *Purpose: Use of HCV AB positive organs (HCV AB+) with active viremia (NAT+) relies on appropriate and timely use of direct acting antiviral therapies (DAA).…
  • 2021 American Transplant Congress

    Evaluation and Experience with Hepatitis C Positive to Negative PancreasTransplantation

    B. K. Lindner, B. Thomas, M. Cooper, S. Yi, P. Abrams

    Medstar Georgetown University Hospital, Washington, DC

    *Purpose: The use of hepatitis C virus (HCV) positive organs for transplant to HCV negative recipients has been reported on and has gained popularity across…
  • 2021 American Transplant Congress

    Successful Single-Center Experience Using HCV+ Organs for Single and Dual-Organ Transplantation

    S. Aslam, C. Logan, N. Law, J. Kerr, J. Kozuch, V. Ajmera, K. Afshar, A. Khan, E. Adler, K. Mekeel, E. Golts, V. Pretorius

    UCSD, San Diego, CA

    *Purpose: National data demonstrate that increasing organ transplantation opportunities exist from hepatitis C virus (HCV)-infected individuals to HCV negative recipients.*Methods: We developed a clinical practice…
  • 2021 American Transplant Congress

    T Cell Repertoire Diversity in HCV-Associated Hepatocellular Carcinoma Patients Waitlisted for Liver Transplantation and Receiving Liver-Directed Therapy

    K. Nunez, T. Sandow, A. Cohen, P. Thevenot

    Ochsner Health, New Orleans, LA

    *Purpose: T cell receptor (TCR) sequencing in hepatocellular carcinoma (HCC) patients revealed a diverse TCR repertoire in hepatitis B-associated HCC-infiltrating T cells. In this study,…
  • 2021 American Transplant Congress

    Processes to Successfully Utilize Hepatitis C (HCV) Infected Donor Kidneys as Standard of Care

    A. Dao1, A. Reyad1, J. Guiteau1, M. Madhrira2, S. Allam2

    1Transplant, Medical City Fort Worth, Fort Worth, TX, 2Tarrant Nephrology Associates, Premier Physicians Group Health, Fort Worth, TX

    *Purpose: Despite robust evidence supporting the safety and efficacy of HCV-infected donor kidneys, great heterogeneity continues to exist regarding centers willingness to utilize these in…
  • 2021 American Transplant Congress

    Comparison of Outcomes of Hepatitis C Virus (hcv) Nucleic Acid (nat) Positive Donor Between Hcv-naïVe and Hcv + Recpients – A Donor Mate Analysis

    J. Kamal, B. Sharma, A. Doyle, A. Kumar, A. Nishio-Lucar, S. Rao

    University of Virginia, Charlottesville, VA

    *Purpose: Despite a growing mismatch between organ need and supply, organs from HCV+ donors were only offered to HCV+ recipients (HCV R+) to avoid complications…
  • 2021 American Transplant Congress

    Not Always as it Seems: Lack of Hepatitis C Virus Transmission from Nucleic Acid Testing Positive Deceased Donors

    A. Nishio Lucar1, A. Kumar1, S. Rao1, V. L. Kelly1, K. Coles2, J. Kamal1, C. W. Green1, A. M. Doyle1

    1Medicine, University of Virginia, Charlottesville, VA, 2University of Virginia, Charlottesville, VA

    *Purpose: Hepatitis C virus (HCV) + organs are increasingly use to transplant HCV naive candidates with good short-term outcomes. HCV transmission with HCV nucleic acid…
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