2021 American Transplant Congress
Not Always as it Seems: Lack of Hepatitis C Virus Transmission from Nucleic Acid Testing Positive Deceased Donors
1Medicine, University of Virginia, Charlottesville, VA, 2University of Virginia, Charlottesville, VA
*Purpose: Hepatitis C virus (HCV) + organs are increasingly use to transplant HCV naive candidates with good short-term outcomes. HCV transmission with HCV nucleic acid…2021 American Transplant Congress
Pharmacokinetic Analysis of Direct Acting Antiviral Use on Weight-Adjusted FK506 Trough/dose Ratios in Obese Kidney Transplant Recipients
*Purpose: Using hepatitis C viremic (HCV) organs in kidney transplant recipients(KTRs) is very important to decrease the number of patients on the waiting list. Direct…2021 American Transplant Congress
Transplantation of Hepatitis C Positive Kidney and Pancreas Allografts Into Hepatitis C Naïve Recipients – A Single Center Experience as a Standard of Care
*Purpose: Transplantation of Hepatitis C positive organs into Hepatitis C naïve recipients is rapidly gaining widespread acceptance. We report our experience with transplanting HCV D+/R-…2021 American Transplant Congress
Comparison of Outcomes of Hepatitis C Virus (hcv) Nucleic Acid (nat) Positive Donor Between Hcv-naïVe and Hcv + Recpients – A Donor Mate Analysis
University of Virginia, Charlottesville, VA
*Purpose: Despite a growing mismatch between organ need and supply, organs from HCV+ donors were only offered to HCV+ recipients (HCV R+) to avoid complications…2021 American Transplant Congress
Successful Single-Center Experience Using HCV+ Organs for Single and Dual-Organ Transplantation
*Purpose: National data demonstrate that increasing organ transplantation opportunities exist from hepatitis C virus (HCV)-infected individuals to HCV negative recipients.*Methods: We developed a clinical practice…2021 American Transplant Congress
T Cell Repertoire Diversity in HCV-Associated Hepatocellular Carcinoma Patients Waitlisted for Liver Transplantation and Receiving Liver-Directed Therapy
Ochsner Health, New Orleans, LA
*Purpose: T cell receptor (TCR) sequencing in hepatocellular carcinoma (HCC) patients revealed a diverse TCR repertoire in hepatitis B-associated HCC-infiltrating T cells. In this study,…2021 American Transplant Congress
Processes to Successfully Utilize Hepatitis C (HCV) Infected Donor Kidneys as Standard of Care
*Purpose: Despite robust evidence supporting the safety and efficacy of HCV-infected donor kidneys, great heterogeneity continues to exist regarding centers willingness to utilize these in…2021 American Transplant Congress
Evaluation and Experience with Hepatitis C Positive to Negative PancreasTransplantation
Medstar Georgetown University Hospital, Washington, DC
*Purpose: The use of hepatitis C virus (HCV) positive organs for transplant to HCV negative recipients has been reported on and has gained popularity across…2021 American Transplant Congress
The Use of Hcv Nat+ Organs in Hcv Negative Recipients with On-site Specialty Pharmacy Services: A Win for the Patient, the Transplant Center, and Society?
Medical University of South Carolina, Charleston, SC
*Purpose: Use of HCV AB positive organs (HCV AB+) with active viremia (NAT+) relies on appropriate and timely use of direct acting antiviral therapies (DAA).…2021 American Transplant Congress
Pilot Study for the Use of Shortened Preemptive Therapy with Glecaprevir/pibrentasvir (g/p) and Ezetimibe in Hepatitis C Seronegative Solid Organ Transplant Recipients (Kidney and Heart) of Hepatitis C Viremic Donors
*Purpose: This prospective study aims to assess the efficacy of preemptive therapy with eight days of a combination of direct-acting antivirals (DAAs) (Mavyret) (Pibrentasvir /Glecaprevir)…
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