2022 American Transplant Congress
Impact of Maintaining Blood Pressure Goals on Graft Function After Kidney Transplant
Temple University Hospital, Philadelphia, PA
*Purpose: Impaired graft function following kidney transplant impacts short- and long-term patient outcomes. Proper management of systolic blood pressure (SBP) in the immediate post-operative period…2022 American Transplant Congress
Controlling Instability at Reperfusion: Another Benefit of Normothermic Machine Perfusion Using OCS Liver
*Purpose: Organ Care System (OCS) Liver is a portable ex-vivo normothermic liver perfusion device recently shown to provide superior donor organ preservation. The impact of…2022 American Transplant Congress
Overexpression of Human Ectonucleoside Triphosphate Diphosphohydrolase 1 (entpd1; Hcd39) Did Not Afford Significant Protection on Porcine Endothelial Cells
*Purpose: The thromboregulatory and anti-inflammatory potential of human CD39 (hCD39) makes it a gene of interest in xenotransplantation. In porcine endothelium, CD39 activity is generally…2022 American Transplant Congress
Brain Death as a Novel Preclinical Human Model for the Advancement of Medicine
*Purpose: For interventions that lack US Food and Drug Administration approval, testing is limited and relies on preclinical animal models to determine safety and efficacy.…2021 American Transplant Congress
The Impact of Thromboelastography on Decreasing Blood Product Usage in Liver Transplantation
*Purpose: Liver dysfunction results in derangement of hemostasis and thrombosis. Thromboelastography (TEG) has emerged as a tool to guide resuscitative efforts. However, its utilization and…2021 American Transplant Congress
Transgenic Overexpression of Human Ectonucleoside Triphosphate Diphosphohydrolase 1 (entpd1, Or Hcd39) in Pig to Primate Xenotransplantation Models
*Purpose: Human CD39 (hCD39) is the gene of interest in xenotransplantation due to its reported capacity to prevent platelet aggregation by metabolizing extracellular ATP to…2021 American Transplant Congress
Kidney Transplantation in Patients with Severe Pulmonary Hypertension: Not an Absolute Contraindication?
*Purpose: Severe pulmonary arterial hypertension (PAH) as defined by a pulmonary artery systolic pressure (PASP) >50mmHg is associated with high peri-operative mortality and thus is…2021 American Transplant Congress
Blood Pressure Variability Immediately After Liver Transplant Predicts the Likelihood of Long-Term Cardiovascular Events
*Purpose: Cardiovascular disease is a leading cause of mortality in liver transplant recipients (LTRs). Adequate blood pressure (BP) control within one year after liver transplant…2021 American Transplant Congress
Admission to the Intensive Care Unit Post-liver Transplantation: One Academic Center’s Experience
Transplant Critical Care, Mayo Clinic, Jacksonville, FL
*Purpose: Historically, liver transplant (LT) patients have been admitted directly from the operating room (OR) to the intensive care unit (ICU) for post-operative complex hemodynamic…2021 American Transplant Congress
Time-averaged Oxygen Saturation During Donor Agonal Phase is Associated with Post-transplant Hepatic Graft Survival
*Purpose: Livers harvested from donors after cardiac death (DCD) are subjected to a period of relative warm ischemia during the agonal phase. There have been…
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