2015 American Transplant Congress
Upregulation of Heart Transplant IL-33 Is Critical in Cardiac Tissue Repair
Starzl Transplantation Institute, Department of Surgery, Univ of Pittsburgh, Pittsburgh, PA.
Background: IL-33 is tissue-derived cytokine whose primary proposed function is to modulate immune responses when released during injury. Delivery of recombinant IL-33 protects cardiac allografts…2015 American Transplant Congress
Factors Influencing Cost Among Kidney, Liver, and Heart Transplant Patients in a Private Payer Setting
1Optum, Minneapolis; 2Saint Louis University, St. Louis.
The factors influencing cost in solid organ transplantation have been evaluated by many individual centers, as well as nationally for Medicare patients. However, the majority…2015 American Transplant Congress
Induction of HO-1 High Expression Enhances the Capacity of Immature Dendritic Cells to Modulate Alloimmune Responses
Background: It has been reported that HO-1 is critical for tolerogenic dendritic cells (tolDCs) to suppress T cell responses and tolDCs will lost their immunoregulatory…2015 American Transplant Congress
Murine Veno-Arterial Extracorporeal Membrane Oxygenation (mVA-ECMO): A Novel Tool to Study the Molecular Biology of Mechanical Circulatory Support
PURPOSE: In recent years, clinical use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has grown. Extracorporeal circulation is an essential component of heart and lung transplantation,…2015 American Transplant Congress
Anti-BTLA Antibody (6B2) Induced Prolongation of Fully MHC-Mismatched Murine Cardiac Allograft and Generation of Foxp3+ Regulatory T Cells
Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…2015 American Transplant Congress
Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allografts by Combination of Anti-BTLA mAb (6B2) and Anti-PD-1 mAb (PIM-2)
Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA) and Programmed death (PD)-1 had been suggested to have immunomodulatory activity. This study investigated the…2015 American Transplant Congress
Recipient Myelomonocytic Cells With Activated Hypoxia-Inducible Factor Alleviate Ischemia-Reperfusion Injury in Mouse Heart Allografts
Aim: To investigate the effect of HIF-1α and -2α activation in myelomonocytic cells during the early phase after ischemia-reperfusion (IRI) injury of mouse allogenic heart…2015 American Transplant Congress
Identification of CXCR5+EBV-Specific CD8+ T Cells in Peripheral Blood of Pediatric Heart Transplant Recipients Correlates With IL-21 Production and EBV Reactivation
Approximately 70% of EBV asymptomatic pediatric heart transplant (HTx) recipients carry chronic EBV loads in peripheral blood. These EBV loads may occur due to impaired…2015 American Transplant Congress
Examining Long-Term Survivors in Combined Heart-Lung Transplantation
The goal of this study was to determine variables associated with mortality in combined heart-lung transplantation (HLT).The United Network for Organ Sharing (UNOS) database was…2015 American Transplant Congress
Liver Allograft Provides Immunoprotection for the Cardiac Allograft in Combined Heart-Liver Transplantation
When transplanted simultaneously, the liver allograft has been thought to have an immunoprotective role on other organs. However, detailed studies on simultaneous heart-liver transplantation (SHLT)…
American Transplant Congress abstracts